2RSK
RNA aptamer against prion protein in complex with the partial binding peptide
Summary for 2RSK
| Entry DOI | 10.2210/pdb2rsk/pdb |
| Descriptor | RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'), partial binding peptide of Major prion protein (2 entities in total) |
| Functional Keywords | aptamer, prion, rna, alzheimer's disease, membrane protein-rna complex, membrane protein/rna |
| Biological source | Bos taurus (Bovine) |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor (By similarity): P10279 |
| Total number of polymer chains | 4 |
| Total formula weight | 10842.15 |
| Authors | Mashima, T.,Nishikawa, F.,Kamatari, Y.O.,Fujiwara, H.,Nishikawa, S.,Kuwata, K.,Katahira, M. (deposition date: 2012-03-08, release date: 2013-02-13, Last modification date: 2023-06-14) |
| Primary citation | Mashima, T.,Nishikawa, F.,Kamatari, Y.O.,Fujiwara, H.,Saimura, M.,Nagata, T.,Kodaki, T.,Nishikawa, S.,Kuwata, K.,Katahira, M. Anti-prion activity of an RNA aptamer and its structural basis Nucleic Acids Res., 41:1355-1362, 2013 Cited by PubMed: 23180780DOI: 10.1093/nar/gks1132 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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