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PDB: 36 results

4W7G
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Crystal Structure of the Dynein Light Intermediate Chain's Conserved Domain
Descriptor: Dynein Light Intermediate Chain
Authors:Schroeder, C.M, Ekiert, D.C, Vale, R.D.
Deposit date:2014-08-22
Release date:2014-10-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region.
Elife, 3, 2014
5J8E
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Crystal structure of human Hook3's conserved Hook domain
Descriptor: Protein Hook homolog 3
Authors:Schroeder, C.M, Ekiert, D.C, Vale, R.D.
Deposit date:2016-04-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3.
J.Cell Biol., 214, 2016
7SAV
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Native mu-conotoxin KIIIA isomer
Descriptor: Mu-conotoxin KIIIA
Authors:Schroeder, C.I, Tran, H.N.T.
Deposit date:2021-09-23
Release date:2022-05-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers.
J.Biol.Chem., 298, 2022
7SAW
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Mu-conotoxin KIIIA isomer 2
Descriptor: Mu-conotoxin KIIIA
Authors:Schroeder, C.I, Tran, H.N.T.
Deposit date:2021-09-23
Release date:2022-05-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers.
J.Biol.Chem., 298, 2022
5WOV
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Solution NMR structure of cyclotide MCoTI-I
Descriptor: Two inhibitor peptide topologies 2
Authors:Schroeder, C.I, Kwon, S.
Deposit date:2017-08-03
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Targeted Delivery of Cyclotides via Conjugation to a Nanobody.
ACS Chem. Biol., 13, 2018
5WOW
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Solution NMR structure of cyclotide MCoTI-I
Descriptor: Two inhibitor peptide topologies 2
Authors:Schroeder, C.I, Kwon, S.
Deposit date:2017-08-03
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Targeted Delivery of Cyclotides via Conjugation to a Nanobody.
ACS Chem. Biol., 13, 2018
6MK5
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Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1
Descriptor: Toxin GTx1-15
Authors:Schroeder, C.I.
Deposit date:2018-09-25
Release date:2018-12-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1.
ACS Chem. Biol., 14, 2019
6MK4
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Solution NMR structure of spider toxin analogue [E17K]ProTx-II
Descriptor: Beta/omega-theraphotoxin-Tp2a
Authors:Schroeder, C.I.
Deposit date:2018-09-25
Release date:2018-12-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1.
ACS Chem. Biol., 14, 2019
6BVU
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SFTI-HFRW-1
Descriptor: Trypsin inhibitor 1 HFRW-1
Authors:Schroeder, C.I.
Deposit date:2017-12-13
Release date:2018-12-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
J.Med.Chem., 61, 2018
6BVW
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SFTI-HFRW-3
Descriptor: Trypsin inhibitor 1 HFRW-3
Authors:Schroeder, C.I.
Deposit date:2017-12-14
Release date:2018-12-19
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
J.Med.Chem., 61, 2018
6BVX
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SFTI-HFRW-2
Descriptor: Trypsin inhibitor 1 HFRW-2
Authors:Schroeder, C.I.
Deposit date:2017-12-14
Release date:2018-12-19
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
J.Med.Chem., 61, 2018
6BVY
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SFTI-HFRW-4
Descriptor: Trypsin inhibitor 1 HFRW-4
Authors:Schroeder, C.I, White, A.
Deposit date:2017-12-14
Release date:2018-04-18
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
J. Med. Chem., 61, 2018
6XN9
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Solution NMR structure of recifin, a cysteine-rich tyrosyl-DNA Phosphodiesterase I modulatory peptide from the marine sponge Axinella sp.
Descriptor: Recifin modulatory peptide
Authors:Schroeder, C.I, Rosengren, K.J, O'Keefe, B.R.
Deposit date:2020-07-02
Release date:2021-02-10
Method:SOLUTION NMR
Cite:Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.
J.Am.Chem.Soc., 142, 2020
2NAV
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NMR solution structure of Ex-4[1-16]/pl14a
Descriptor: Exendin-4, Alpha/kappa-conotoxin pl14a chimera
Authors:Schroeder, C.I, Swedberg, J.E, Craik, D.J.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2016-08-17
Method:SOLUTION NMR
Cite:Truncated Glucagon-like Peptide-1 and Exendin-4 alpha-Conotoxin pl14a Peptide Chimeras Maintain Potency and alpha-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.
J.Biol.Chem., 291, 2016
2NAW
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NMR solution structure of Exendin-4/conotoxin chimera (Ex-4[1-27]/pl14a)
Descriptor: Exendin-4, Alpha/kappa-conotoxin pl14a chimera
Authors:Schroeder, C.I, Swedberg, J.E, Craik, D.J.
Deposit date:2016-01-12
Release date:2016-05-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Truncated Glucagon-like Peptide-1 and Exendin-4 alpha-Conotoxin pl14a Peptide Chimeras Maintain Potency and alpha-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.
J.Biol.Chem., 291, 2016
6WQR
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NMR solution structure of leech peptide HSTX-I
Descriptor: HSTX-I
Authors:Schroeder, C.I, McMahon, K.L.
Deposit date:2020-04-29
Release date:2020-06-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Pharmacological activity and NMR solution structure of the leech peptide HSTX-I.
Biochem Pharmacol, 181, 2020
2N7F
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NMR solution structure of muO-conotoxin MfVIA
Descriptor: muO-conotoxin MfVIA
Authors:Schroeder, C.I, Mobli, M.
Deposit date:2015-09-09
Release date:2016-04-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Development of a mu O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
J.Biol.Chem., 291, 2016
6X8R
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Pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor
Descriptor: SxIIIC peptide
Authors:Schroeder, C.I, McMahon, K.L.
Deposit date:2020-06-01
Release date:2020-10-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery, Pharmacological Characterisation and NMR Structure of the Novel μ-Conotoxin SxIIIC, a Potent and Irreversible Na V Channel Inhibitor.
Biomedicines, 8, 2020
2MDQ
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A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors
Descriptor: Alpha-conotoxin-like
Authors:Schroeder, C.I.
Deposit date:2013-09-16
Release date:2014-02-12
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:A novel alpha 4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha 3 beta 2 vs. alpha 6/ alpha 3 beta 2 beta 3 nicotinic acetylcholine receptors.
Faseb J., 28, 2014
2MG9
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Truncated EGF-A
Descriptor: CALCIUM ION, Low-density lipoprotein receptor
Authors:Schroeder, C.I, Rosengren, K.
Deposit date:2013-10-30
Release date:2014-04-02
Method:SOLUTION NMR
Cite:Design and Synthesis of Truncated EGF-A Peptides that Restore LDL-R Recycling in the Presence of PCSK9 In Vitro.
Chem.Biol., 21, 2014
2MFA
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Mambalgin-2
Descriptor: Mambalgin-2
Authors:Schroeder, C.I, Rash, L.D, Vila-Farres, X, Rosengren, K.J, Mobli, M, King, G.F, Alewood, P.F, Craik, D.J, Durek, T.
Deposit date:2013-10-08
Release date:2014-01-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.
Angew.Chem.Int.Ed.Engl., 53, 2014
2N9T
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BU of 2n9t by Molmil
NMR solution structure of ProTx-II
Descriptor: Beta/omega-theraphotoxin-Tp2a
Authors:Schroeder, C.I.
Deposit date:2015-12-08
Release date:2016-07-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
J.Biol.Chem., 291, 2016
1TTK
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NMR solution structure of omega-conotoxin MVIIA, a N-type calcium channel blocker
Descriptor: Omega-conotoxin MVIIa
Authors:Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
Deposit date:2004-06-22
Release date:2004-07-06
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
1TT3
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BU of 1tt3 by Molmil
NMR soulution structure of omega-conotoxin [K10]MVIIA
Descriptor: Omega-conotoxin MVIIa
Authors:Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
Deposit date:2004-06-21
Release date:2004-07-06
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
5WE3
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Solution NMR structure of PaurTx-3
Descriptor: Beta-theraphotoxin-Ps1a
Authors:Agwa, A.J, Schroeder, C.I.
Deposit date:2017-07-06
Release date:2017-09-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins.
Toxins (Basel), 9, 2017

 

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