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2N9T

NMR solution structure of ProTx-II

Summary for 2N9T
Entry DOI10.2210/pdb2n9t/pdb
NMR InformationBMRB: 25917
DescriptorBeta/omega-theraphotoxin-Tp2a (1 entity in total)
Functional Keywordstoxin, cystine knot
Biological sourceThrixopelma pruriens (green velvet)
Cellular locationSecreted : P83476
Total number of polymer chains1
Total formula weight3839.69
Authors
Schroeder, C.I. (deposition date: 2015-12-08, release date: 2016-07-06, Last modification date: 2023-06-14)
Primary citationHenriques, S.T.,Deplazes, E.,Lawrence, N.,Cheneval, O.,Chaousis, S.,Inserra, M.,Thongyoo, P.,King, G.F.,Mark, A.E.,Vetter, I.,Craik, D.J.,Schroeder, C.I.
Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
J.Biol.Chem., 291:17049-17065, 2016
Cited by
PubMed: 27311819
DOI: 10.1074/jbc.M116.729095
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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