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PDB: 34 results

1FKF
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ATOMIC STRUCTURE OF FKBP-FK506, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX
Descriptor: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN
Authors:Vanduyne, G.D, Standaert, R.F, Karplus, P.A, Schreiber, S.L, Clardy, J.
Deposit date:1991-05-07
Release date:1991-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.
Science, 252, 1991
1TYN
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ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS
Descriptor: BETA-TRYPSIN, CYCLOTHEONAMIDE A
Authors:Lee, A.Y, Hagihara, M, Karmacharya, R, Albers, M.W, Schreiber, S.L, Clardy, J.
Deposit date:1994-09-19
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic Structure of the Trypsin-Cyclotheonamide a Complex: Lessons for the Design of Serine Protease Inhibitors
J.Am.Chem.Soc., 115, 1993
1OMB
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BU of 1omb by Molmil
SEQUENTIAL ASSIGNMENT AND STRUCTURE DETERMINATION OF SPIDER TOXIN OMEGA-AGA-IVB
Descriptor: OMEGA-AGA-IVB
Authors:Yu, H, Rosen, M.K, Schreiber, S.L.
Deposit date:1993-09-09
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential assignment and structure determination of spider toxin omega-Aga-IVB.
Biochemistry, 32, 1993
1OMA
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SEQUENTIAL ASSIGNMENT AND STRUCTURE DETERMINATION OF SPIDER TOXIN OMEGA-AGA-IVB
Descriptor: OMEGA-AGA-IVB
Authors:Yu, H, Rosen, M.K, Schreiber, S.L.
Deposit date:1993-09-09
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential assignment and structure determination of spider toxin omega-Aga-IVB.
Biochemistry, 32, 1993
1PHT
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BU of 1pht by Molmil
PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN, RESIDUES 1-85
Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT
Authors:Liang, J, Chen, J.K, Schreiber, S.L, Clardy, J.
Deposit date:1995-08-17
Release date:1995-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of P13K SH3 domain at 20 angstroms resolution.
J.Mol.Biol., 257, 1996
1FAV
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THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE
Descriptor: HIV-1 ENVELOPE PROTEIN CHIMERA, PROTEIN (TRANSMEMBRANE GLYCOPROTEIN)
Authors:Zhou, G, Ferrer, M, Chopra, R, Strassmaier, T, Weissenhorn, W, Skehel, J.J, Oprian, D, Schreiber, S.L, Harrison, S.C, Wiley, D.C.
Deposit date:2000-07-13
Release date:2000-08-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.
Bioorg.Med.Chem., 8, 2000
1FKB
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ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX
Descriptor: FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
Authors:Van Duyne, G.D, Standaert, R.F, Schreiber, S.L, Clardy, J.C.
Deposit date:1992-07-02
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic Structure of the Rapamycin Human Immunophilin Fkbp-12 Complex
J.Am.Chem.Soc., 113, 1991
1FAP
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THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP
Descriptor: FK506-BINDING PROTEIN, FRAP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
Authors:Choi, J, Chen, J, Schreiber, S.L, Clardy, J.
Deposit date:1996-03-15
Release date:1997-07-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP.
Science, 273, 1996
1FWQ
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SOLUTION STRUCTURE OF HUMAN MSS4, A GUANINE NUCLEOTIDE EXCHANGE FACTOR FOR RAB PROTEINS
Descriptor: GUANINE NUCLEOTIDE EXCHANGE FACTOR, ZINC ION
Authors:Yu, H, Schreiber, S.L.
Deposit date:2000-09-24
Release date:2000-10-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of guanine-nucleotide-exchange factor human Mss4 and identification of its Rab-interacting surface.
Nature, 376, 1995
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