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PDB: 101 件
6EWY
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RipA Peptidoglycan hydrolase (Rv1477, Mycobacterium tuberculosis) N-terminal domain
分子名称: Peptidoglycan endopeptidase RipA
著者Schnell, R, Steiner, E.M, Schneider, G, Guy, J, Bourenkov, G.
登録日2017-11-07
公開日2018-05-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of the N-terminal module of the cell wall hydrolase RipA and its role in regulating catalytic activity.
Proteins, 86, 2018
8BBJ
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BU of 8bbj by Molmil
Secretagogin (mouse) in complex with its target peptide from Syntaxin-4
分子名称: CACODYLATE ION, CALCIUM ION, Green fluorescent protein,Syntaxin-4, ...
著者Schnell, R, Szodorai, E.
登録日2022-10-13
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues.
Proc.Natl.Acad.Sci.USA, 121, 2024
8BAN
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BU of 8ban by Molmil
Secretagogin (mouse) in complex with its target peptide from SNAP-25
分子名称: CALCIUM ION, Green fluorescent protein,Synaptosomal-associated protein 25, Secretagogin
著者Schnell, R, Szodorai, E.
登録日2022-10-11
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues.
Proc.Natl.Acad.Sci.USA, 121, 2024
8BAV
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Secretagogin (human) in complex with its target peptide from SNAP-25
分子名称: ACETATE ION, CALCIUM ION, Green fluorescent protein,Synaptosomal-associated protein 25, ...
著者Schnell, R, Szodorai, E.
登録日2022-10-12
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues.
Proc.Natl.Acad.Sci.USA, 121, 2024
1ZJ8
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BU of 1zj8 by Molmil
Structure of Mycobacterium tuberculosis NirA protein
分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, Probable ferredoxin-dependent nitrite reductase NirA, ...
著者Schnell, R, Sandalova, T, Hellman, U, Lindqvist, Y, Schneider, G, Structural Proteomics in Europe (SPINE)
登録日2005-04-28
公開日2005-05-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis Is a Sulfite Reductase with a Covalent Cys-Tyr Bond in the Active Site
J.Biol.Chem., 280, 2005
1ZJ9
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BU of 1zj9 by Molmil
Structure of Mycobacterium tuberculosis NirA protein
分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, Probable ferredoxin-dependent nitrite reductase NirA, ...
著者Schnell, R, Sandalova, T, Hellman, U, Lindqvist, Y, Schneider, G.
登録日2005-04-28
公開日2005-05-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis Is a Sulfite Reductase with a Covalent Cys-Tyr Bond in the Active Site
J.Biol.Chem., 280, 2005
7QZJ
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1.55 A X-ray crystallographic structure of SapH from Streptomyces sp. (HPH0547) involved in Pseudouridimycin biosynthesis
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, GLYCEROL, ...
著者Schnell, R, Schneider, G.
登録日2022-01-31
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway.
Acs Chem.Biol., 18, 2023
7A10
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LppS with covalent adduct derived from 1g
分子名称: 4-methoxycyclohexa-2,5-diene-1-thione, L,D-transpeptidase 2
著者Schnell, R, Steiner, E.M.
登録日2020-08-11
公開日2021-04-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.
Cell Chem Biol, 28, 2021
7A11
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LppS with covalent adduct derived from 1E
分子名称: ACETATE ION, L,D-transpeptidase 2, propane-1-thiol
著者Schnell, R, Steiner, E.M.
登録日2020-08-11
公開日2021-04-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.
Cell Chem Biol, 28, 2021
7A0Z
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LppS with covalent adduct derived from 1b
分子名称: L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol
著者Schnell, R, Steiner, E.M.
登録日2020-08-11
公開日2021-04-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.
Cell Chem Biol, 28, 2021
7A1C
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LdtMT2 with covalent adduct derived from N-Thio-beta-lactam 1a
分子名称: DIMETHYL SULFOXIDE, L,D-transpeptidase 2
著者Schnell, R, Steiner, E.M.
登録日2020-08-12
公開日2021-04-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.
Cell Chem Biol, 28, 2021
7A1E
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LppS with covalent adduct derived from 1c
分子名称: ACETATE ION, L,D-transpeptidase 2, phenylmethanethiol
著者Schnell, R, Steiner, E.M.
登録日2020-08-12
公開日2021-04-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.
Cell Chem Biol, 28, 2021
5I7R
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BU of 5i7r by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 2 [3-(3-([1,1'-biphenyl]-3-yl)ureido)benzoic acid]
分子名称: 3-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}benzoic acid, ACETATE ION, O-phosphoserine sulfhydrylase, ...
著者Schnell, R, Maric, S, Schneider, G.
登録日2016-02-18
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7H
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Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 6 [3-(3-(4-Bromophenyl)ureido)benzoic acid]
分子名称: 3-{[(4-bromophenyl)carbamoyl]amino}benzoic acid, CHLORIDE ION, O-phosphoserine sulfhydrylase, ...
著者Schnell, R, Maric, S, Schneider, G.
登録日2016-02-17
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7O
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Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 7 [3-(3-(4-Chlorophenyl)ureido)benzoic acid]
分子名称: 3-{[(4-chlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
著者Schnell, R, Maric, S, Schneider, G.
登録日2016-02-18
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I6D
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BU of 5i6d by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 5 [3-(3-(p-Tolyl)ureido) benzoic acid]
分子名称: 3-{[(4-methylphenyl)carbamoyl]amino}benzoic acid, GLYCEROL, O-phosphoserine sulfhydrylase, ...
著者Schnell, R, Maric, S, Schneider, G.
登録日2016-02-16
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7A
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BU of 5i7a by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 1 [3-(3-(3,4-Dichlorophenyl)ureido)benzoic acid]
分子名称: 3-{[(3,4-dichlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
著者Schnell, R, Maric, S, Schneider, G.
登録日2016-02-17
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5IWC
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BU of 5iwc by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 3 [4-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
分子名称: 4-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
著者Schnell, R, Maric, S, Lindqvist, Y, Schneider, G.
登録日2016-03-22
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
3PBC
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Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis at 1.38 resolution
分子名称: INVASION PROTEIN
著者Schnell, R, Both, D, Schneider, G.
登録日2010-10-20
公開日2011-08-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB.
J.Mol.Biol., 413, 2011
3PBI
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Structure of the peptidoglycan hydrolase RipB (Rv1478) from Mycobacterium tuberculosis at 1.6 resolution
分子名称: INVASION PROTEIN
著者Schnell, R, Both, D, Schneider, G.
登録日2010-10-20
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB.
J.Mol.Biol., 413, 2011
3QZE
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Crystal Structure of DapA (PA1010) at 1.6 A resolution
分子名称: CHLORIDE ION, Dihydrodipicolinate synthase
著者Schnell, R, Sandalova, T, Schneider, G.
登録日2011-03-05
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion.
Plos One, 7, 2012
4ETR
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BU of 4etr by Molmil
X-ray structure of PA2169 from Pseudomonas aeruginosa
分子名称: Putative uncharacterized protein
著者Schnell, R, Sandalova, T, Lindqvist, Y, Schneider, G.
登録日2012-04-24
公開日2013-01-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4ES6
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BU of 4es6 by Molmil
Crystal structure of HemD (PA5259) from Pseudomonas aeruginosa (PAO1) at 2.22 A resolution
分子名称: CHLORIDE ION, Uroporphyrinogen-III synthase
著者Schnell, R, Schneider, G.
登録日2012-04-22
公開日2013-01-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4EXB
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BU of 4exb by Molmil
Putative aldo-keto reductase from Pseudomona aeruginosa
分子名称: Putative uncharacterized protein
著者Schnell, R, Schneider, G, Sandalova, T.
登録日2012-04-30
公開日2013-01-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4UMJ
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Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound ibandronic acid molecules.
分子名称: GERANYLTRANSTRANSFERASE, IBANDRONATE, MAGNESIUM ION
著者Schmidberger, J.W, Schnell, R, Schneider, G.
登録日2014-05-18
公開日2015-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 71, 2015

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