8R2J

X-ray crystallographic structure of SwaQ2 in complex with NADP+ and doxorubicin

Summary for 8R2J

• Entry DOI: 10.2210/pdb8r2j/pdb
• Descriptor: NmrA family transcriptional regulator, DOXORUBICIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• Functional Keywords: polyketide, antibiotic, biosynthesis, biosynthetic protein
• Biological source: Streptomyces swartbergensis
• Total number of polymer chains: 2
• Total formula weight: 66537.02

Authors

Schnell, R.,Schneider, G. (deposition date: 2023-11-06, release date: 2024-08-07)

• Primary citation: Wandi, B.N.,Dinis, P.,Siitonen, V.,Schneider, G.,Schnell, R.,Metsa-Ketele, M.; Mechanism of Two-Component Mono-Oxygenases Involved in Anthracycline 1-Hydroxylation; Acs Catalysis, 2024; DOI: 10.1021/acscatal.4c02623

Experimental method

X-RAY DIFFRACTION (2.4 Å)