1C41
 
 | | CRYSTAL STRUCTURES OF A PENTAMERIC FUNGAL AND AN ICOSAHEDRAL PLANT LUMAZINE SYNTHASE REVEALS THE STRUCTURAL BASIS FOR DIFFERENCES IN ASSEMBLY | | 分子名称: | 5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, LUMAZINE SYNTHASE, SULFATE ION | | 著者 | Persson, K, Schneider, G, Jordan, D.B, Viitanen, P.V, Sandalova, T. | | 登録日 | 1999-08-03 | | 公開日 | 2000-08-06 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure analysis of a pentameric fungal and an icosahedral plant lumazine synthase reveals the structural basis for differences in assembly
Protein Sci., 8, 1999
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6T6N
 | | Crystal structure of Klebsiella pneumoniae FabG2(NADH-dependent) in complex with NADH at 2.5 A resolution | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-oxoacyl-[acyl-carrier protein] reductase, D-MALATE, ... | | 著者 | Vella, P, Schnell, R, Lindqvist, Y, Schneider, G. | | 登録日 | 2019-10-18 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens.
Bioorg.Med.Chem., 30, 2021
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1MLY
 | | Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the cis isomer of amiclenomycin | | 分子名称: | 7,8-diamino-pelargonic acid aminotransferase, CIS-AMICLENOMYCIN, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Sandmark, J, Mann, S, Marquet, A, Schneider, G. | | 登録日 | 2002-09-02 | | 公開日 | 2002-12-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin
J.Biol.Chem., 277, 2002
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1MGV
 | | Crystal Structure of the R391A Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | 7,8-diamino-pelargonic acid aminotransferase, ISOPROPYL ALCOHOL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Eliot, A.C, Sandmark, J, Schneider, G, Kirsch, J.F. | | 登録日 | 2002-08-16 | | 公開日 | 2002-11-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Dual-Specific Active Site of 7,8-Diaminopelargonic Acid Synthase and the Effect of the R391A Mutation
Biochemistry, 41, 2002
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1S07
 | | Crystal Structure of the R253A Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ISOPROPYL ALCOHOL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Sandmark, J, Eliot, A.C, Famm, K, Schneider, G, Kirsch, J.F. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1TW2
 | | Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET) | | 分子名称: | Carminomycin 4-O-methyltransferase, METHYL (4R)-2-ETHYL-2,5,12-TRIHYDROXY-7-METHOXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-RIBO-HEXOPYRANOSYL]OXY}-1H,2H,3H,4H,6H,11H-TETRACENE-1-CARBOXYLATE, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Jansson, A, Koskiniemi, H, Mantsala, P, Niemi, J, Schneider, G, Structural Proteomics in Europe (SPINE) | | 登録日 | 2004-06-30 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products
J.Biol.Chem., 279, 2004
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1CK7
 | | GELATINASE A (FULL-LENGTH) | | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN (GELATINASE A), ... | | 著者 | Morgunova, E, Tuuttila, A, Bergmann, U, Isupov, M, Lindqvist, Y, Schneider, G, Tryggvason, K. | | 登録日 | 1999-04-28 | | 公開日 | 1999-08-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed.
Science, 284, 1999
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1TW3
 | | Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET) | | 分子名称: | Carminomycin 4-O-methyltransferase, METHYL (4R)-2-ETHYL-2,5,12-TRIHYDROXY-7-METHOXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-RIBO-HEXOPYRANOSYL]OXY}-1H,2H,3H,4H,6H,11H-TETRACENE-1-CARBOXYLATE, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Jansson, A, Koskiniemi, H, Mantsala, P, Niemi, J, Schneider, G. | | 登録日 | 2004-06-30 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products
J.Biol.Chem., 279, 2004
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1E5Q
 | | Ternary complex of saccharopine reductase from Magnaporthe grisea, NADPH and saccharopine | | 分子名称: | N-(5-AMINO-5-CARBOXYPENTYL)GLUTAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Saccharopine dehydrogenase [NADP(+), ... | | 著者 | Johansson, E, Steffens, J.J, Lindqvist, Y, Schneider, G. | | 登録日 | 2000-07-28 | | 公開日 | 2000-12-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Saccharopine Reductase from Magnaporthe Grisea, an Enzyme of the Alpha-Aminoadipate Pathway of Lysine Biosynthesis
Structure, 8, 2000
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1S08
 | | Crystal Structure of the D147N Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | 著者 | Sandmark, J, Eliot, A.C, Famm, K, Schneider, G, Kirsch, J.F. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1S0A
 | | Crystal Structure of the Y17F Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | 著者 | Sandmark, J, Eliot, A.C, Famm, K, Schneider, G, Kirsch, J.F. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1S09
 | | Crystal Structure of the Y144F Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | 著者 | Sandmark, J, Eliot, A.C, Famm, K, Schneider, G, Kirsch, J.F. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1BR9
 | | HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2 | | 分子名称: | METALLOPROTEINASE-2 INHIBITOR | | 著者 | Tuuttila, A, Morgunova, E, Bergmann, U, Lindqvist, Y, Tryggvason, K, Schneider, G. | | 登録日 | 1998-08-28 | | 公開日 | 1999-05-04 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 A resolution.
J.Mol.Biol., 284, 1998
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1S06
 | | Crystal Structure of the R253K Mutant of 7,8-Diaminopelargonic Acid Synthase | | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | 著者 | Sandmark, J, Eliot, A.C, Famm, K, Schneider, G, Kirsch, J.F. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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6T65
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1U08
 | | Crystal Structure and Reactivity of YbdL from Escherichia coli Identify a Methionine Aminotransferase Function. | | 分子名称: | Hypothetical aminotransferase ybdL, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Dolzan, M, Johansson, K, Roig-Zamboni, V, Campanacci, V, Tegoni, M, Schneider, G, Cambillau, C. | | 登録日 | 2004-07-13 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function
FEBS Lett., 571, 2004
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6T5X
 | | Crystal structure of Salmonella typhimurium FabG in complex with NADPH at 1.5 A resolution | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] reductase FabG, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Vella, P, Schnell, R, Schneider, G. | | 登録日 | 2019-10-17 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens.
Bioorg.Med.Chem., 30, 2021
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6T6P
 | | Crystal structure of Klebsiella pneumoniae FabG2(NADH-dependent) at 1.57 A resolution | | 分子名称: | 3-oxoacyl-[acyl-carrier protein] reductase, GLYCEROL, PHOSPHATE ION | | 著者 | Vella, P, Schnell, R, Lindqvist, Y, Schneider, G. | | 登録日 | 2019-10-18 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens.
Bioorg.Med.Chem., 30, 2021
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6T7M
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1A82
 | | DETHIOBIOTIN SYNTHETASE FROM ESCHERICHIA COLI, COMPLEX WITH SUBSTRATES ATP AND DIAMINOPELARGONIC ACID | | 分子名称: | 7,8-DIAMINO-NONANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, DETHIOBIOTIN SYNTHETASE, ... | | 著者 | Kaeck, H, Gibson, K.J, Lindqvist, Y, Schneider, G. | | 登録日 | 1998-03-31 | | 公開日 | 1999-05-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Snapshot of a phosphorylated substrate intermediate by kinetic crystallography.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1B3N
 | | BETA-KETOACYL CARRIER PROTEIN SYNTHASE AS A DRUG TARGET, IMPLICATIONS FROM THE CRYSTAL STRUCTURE OF A COMPLEX WITH THE INHIBITOR CERULENIN. | | 分子名称: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, PROTEIN (KETOACYL ACYL CARRIER PROTEIN SYNTHASE 2) | | 著者 | Moche, M, Schneider, G, Edwards, P, Dehesh, K, Lindqvist, Y. | | 登録日 | 1998-12-14 | | 公開日 | 1999-04-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase.
J.Biol.Chem., 274, 1999
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1DAK
 | | DETHIOBIOTIN SYNTHETASE FROM ESCHERICHIA COLI, COMPLEX REACTION INTERMEDIATE ADP AND MIXED ANHYDRIDE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DETHIOBIOTIN SYNTHETASE, MAGNESIUM ION, ... | | 著者 | Kaeck, H, Gibson, K.J, Lindqvist, Y, Schneider, G. | | 登録日 | 1998-03-31 | | 公開日 | 1999-04-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Snapshot of a phosphorylated substrate intermediate by kinetic crystallography.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1E3L
 | | P47H mutant of mouse class II alcohol dehydrogenase complex with NADH | | 分子名称: | ALCOHOL DEHYDROGENASE, CLASS II, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Svensson, S, Hoog, J.O, Schneider, G, Sandalova, T. | | 登録日 | 2000-06-19 | | 公開日 | 2000-09-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency
J.Mol.Biol., 302, 2000
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1E3I
 | | Mouse class II alcohol dehydrogenase complex with NADH and inhibitor | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALCOHOL DEHYDROGENASE, CLASS II, ... | | 著者 | Svensson, S, Hoog, J.O, Schneider, G, Sandalova, T. | | 登録日 | 2000-06-16 | | 公開日 | 2000-09-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency
J.Mol.Biol., 302, 2000
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1E3E
 | | Mouse class II alcohol dehydrogenase complex with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALCOHOL DEHYDROGENASE, CLASS II, ... | | 著者 | Svensson, S, Hoeoeg, J.O, Schneider, G, Sandalova, T. | | 登録日 | 2000-06-14 | | 公開日 | 2000-09-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Crystal Structure of Mouse Class II Alcohol Dehydrogenase Reveal Determinants of Substrate Specificity and Catalytic Efficiency
J.Mol.Biol., 302, 2000
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