6T6P
Crystal structure of Klebsiella pneumoniae FabG2(NADH-dependent) at 1.57 A resolution
Summary for 6T6P
Entry DOI | 10.2210/pdb6t6p/pdb |
Descriptor | 3-oxoacyl-[acyl-carrier protein] reductase, PHOSPHATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | fatty acid biosynthesis, fabg, (3-oxoacyl-(acyl-carrier-protein) reductase), nadh, nadph, complex, fas-ii, biosynthetic protein |
Biological source | Klebsiella pneumoniae 30684/NJST258_2 |
Total number of polymer chains | 4 |
Total formula weight | 104887.18 |
Authors | Vella, P.,Schnell, R.,Lindqvist, Y.,Schneider, G. (deposition date: 2019-10-18, release date: 2020-11-18, Last modification date: 2024-01-24) |
Primary citation | Vella, P.,Rudraraju, R.S.,Lundback, T.,Axelsson, H.,Almqvist, H.,Vallin, M.,Schneider, G.,Schnell, R. A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens. Bioorg.Med.Chem., 30:115898-115898, 2021 Cited by PubMed: 33388594DOI: 10.1016/j.bmc.2020.115898 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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