6T7M
Crystal structure of Salmonella typhimurium FabG at 2.65 A resolution
Summary for 6T7M
| Entry DOI | 10.2210/pdb6t7m/pdb |
| Descriptor | 3-oxoacyl-[acyl-carrier-protein] reductase FabG (2 entities in total) |
| Functional Keywords | fatty acid biosynthesis, fabg, (3-oxoacyl-(acyl-carrier-protein) reductase), nadp, nadph, complex, fas-ii, biosynthetic protein |
| Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
| Total number of polymer chains | 4 |
| Total formula weight | 112520.11 |
| Authors | Vella, P.,Schnell, R.,Schneider, G. (deposition date: 2019-10-22, release date: 2020-11-18, Last modification date: 2024-01-24) |
| Primary citation | Vella, P.,Rudraraju, R.S.,Lundback, T.,Axelsson, H.,Almqvist, H.,Vallin, M.,Schneider, G.,Schnell, R. A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens. Bioorg.Med.Chem., 30:115898-115898, 2021 Cited by PubMed: 33388594DOI: 10.1016/j.bmc.2020.115898 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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