1MLY

Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the cis isomer of amiclenomycin

Summary for 1MLY

Related1qj5 1dty 1qj3 1mgv 1mlz
Descriptor7,8-diamino-pelargonic acid aminotransferase, CIS-AMICLENOMYCIN, SODIUM ION, ... (5 entities in total)
Functional Keywordsaminotransferase, fold type i, subclass ii, amiclenomycin, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm  P12995
Total number of polymer chains2
Total molecular weight95553.54
Authors
Sandmark, J.,Mann, S.,Marquet, A.,Schneider, G. (deposition date: 2002-09-02, release date: 2002-12-04, Last modification date: 2018-03-07)
Primary citation
Sandmark, J.,Mann, S.,Marquet, A.,Schneider, G.
Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin
J.Biol.Chem., 277:43352-43358, 2002
PubMed: 12218056 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M207239200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.81 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.225100.6%3.9%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution