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PDB: 44 件

2ADM
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ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
分子名称: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYLMETHIONINE
著者Schluckebier, G, Saenger, W.
登録日1996-07-15
公開日1997-01-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
3ZU1
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Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Schluckebier, G, Whittingham, J.
登録日2011-07-13
公開日2011-08-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin
To be Published
1AQI
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STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
分子名称: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYL-L-HOMOCYSTEINE
著者Schluckebier, G, Saenger, W.
登録日1996-07-25
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
1AQJ
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STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
分子名称: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, SINEFUNGIN
著者Schluckebier, G, Saenger, W.
登録日1996-07-25
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
8RRP
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Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin
分子名称: ACETATE ION, Insulin, Insulin B chain
著者Schluckebier, G, Johansson, E.
登録日2024-01-23
公開日2024-07-10
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.
Nat Commun, 15, 2024
8CN9
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Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII
分子名称: CALCIUM ION, CESIUM ION, Coagulation factor VII, ...
著者Schluckebier, G, Johansson, E.
登録日2023-02-22
公開日2023-12-27
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders.
Nat Cardiovasc Res, 3, 2024
1TRP
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BU of 1trp by Molmil
X-RAY CRYSTALLOGRAPHIC AND CALORIMERIC STUDIES OF THE EFFECTS OF THE MUTATION TRP 59 TYR IN RIBONUCLEASE T1
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 ISOZYME
著者Schluckebier, G, Saenger, W.
登録日1993-07-06
公開日1994-04-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray crystallographic and calorimetric studies of the effects of the mutation Trp59-->Tyr in ribonuclease T1.
Eur.J.Biochem., 220, 1994
1QAN
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称: ACETATE ION, ERMC' METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE
著者Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
登録日1999-03-26
公開日2000-03-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAO
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称: ERMC' METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
著者Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
登録日1999-03-26
公開日2000-03-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAM
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称: ACETATE ION, ERMC' METHYLTRANSFERASE
著者Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
登録日1999-03-25
公開日2000-03-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAQ
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THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
分子名称: ERMC' RRNA METHYLTRANSFERASE, SINEFUNGIN
著者Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
登録日1999-03-28
公開日2000-03-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
8PJH
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Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation
分子名称: Insulin
著者Schluckebier, G, Johansson, E.
登録日2023-06-23
公開日2023-11-08
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
8PJC
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Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation
分子名称: Insulin
著者Schluckebier, G, Johansson, E.
登録日2023-06-23
公開日2023-11-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
5E94
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BU of 5e94 by Molmil
Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain
分子名称: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Glucagon-like peptide 1 receptor
著者Soroka, V, Schluckebier, G, Reedtz-Runge, S.
登録日2015-10-14
公開日2016-08-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.
Sci Rep, 6, 2016
2ERC
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BU of 2erc by Molmil
CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE
分子名称: RRNA METHYL TRANSFERASE
著者Bussiere, D.E, Muchmore, S.W, Dealwis, C.G, Schluckebier, G, Abad-Zapatero, C.
登録日1998-03-13
公開日1999-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Biochemistry, 37, 1998
4IDW
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BU of 4idw by Molmil
Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy
分子名称: Insulin A chain, Insulin B chain, ZINC ION
著者Margiolaki, I, Giannopoulou, A.E, Wright, J.P, Knight, L, Norrman, M, Schluckebier, G, Fitch, A, Von Dreele, R.B.
登録日2012-12-13
公開日2013-06-05
最終更新日2024-10-30
実験手法POWDER DIFFRACTION
主引用文献High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin
Acta Crystallogr.,Sect.D, 69, 2013
8CHE
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BU of 8che by Molmil
TLT-1 binding Fab of the bispecific antibody HMB-001 in complex with the TLT-1 stalk peptide
分子名称: Fab heavy chain, Fab light chain, Trem-like transcript 1 protein
著者Johansson, E, Schluckebier, G.
登録日2023-02-07
公開日2023-12-27
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders.
Nat Cardiovasc Res, 3, 2024
6GNQ
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Monoclinic crystalline form of human insulin, complexed with meta-cresol
分子名称: 1,2-ETHANEDIOL, Insulin, M-CRESOL, ...
著者Margiolaki, I, Karavassili, F, Valmas, A, Dimarogona, M, Giannopoulou, A.E, Fili, S, Schluckebier, G, Norrman, M, Beckers, D, Fitch, A.N.
登録日2018-05-31
公開日2019-06-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Monoclinic crystalline form of human insulin, complexed with meta-cresol
To Be Published
6FEY
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BU of 6fey by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin
分子名称: Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5
著者Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D.
登録日2018-01-03
公開日2018-09-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
6FF3
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Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I
分子名称: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2
著者Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M.
登録日2018-01-03
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
7PG2
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Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1
分子名称: Insulin, Isoform Short of Insulin receptor
著者Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
登録日2021-08-12
公開日2022-02-02
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
7PG0
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BU of 7pg0 by Molmil
Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin with visible ddm micelle, conf 1
分子名称: Insulin, Isoform Short of Insulin receptor
著者Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
登録日2021-08-12
公開日2022-02-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
7PG3
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Low resolution Cryo-EM structure of the full-length insulin receptor bound to 3 insulin, conf 2
分子名称: Insulin, Isoform Short of Insulin receptor
著者Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
登録日2021-08-12
公開日2022-02-02
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
7PG4
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BU of 7pg4 by Molmil
Low resolution Cryo-EM structure of the full-length insulin receptor bound to 2 insulin, conf 3
分子名称: Insulin, Isoform Short of Insulin receptor
著者Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
登録日2021-08-12
公開日2022-02-02
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
8PI5
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Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation
分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ...
著者Johansson, E, Schluckebier, G.
登録日2023-06-21
公開日2023-11-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024

 

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