7QKV
 
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7QK2
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7QKZ
 | | In vitro assembled 305-379 tau filaments (27a) | | Descriptor: | Microtubule-associated protein tau | | Authors: | Lovestam, S, Scheres, S.H.W. | | Deposit date: | 2021-12-19 | | Release date: | 2022-02-16 | | Last modified: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
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7QK3
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7QWL
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7QKH
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7QVF
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7QWG
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7QVC
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7QJX
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7QKJ
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7QWM
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5GAO
 | | Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP | | Descriptor: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ... | | Authors: | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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5GAN
 | | The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ... | | Authors: | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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5FKW
 | | cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon) | | Descriptor: | DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ... | | Authors: | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | | Deposit date: | 2015-10-20 | | Release date: | 2015-11-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
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5FKV
 | | cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex) | | Descriptor: | DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ... | | Authors: | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | | Deposit date: | 2015-10-20 | | Release date: | 2015-11-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.04 Å) | | Cite: | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
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5FN4
 | | Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble | | Descriptor: | Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ... | | Authors: | Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5FN5
 | | Cryo-EM structure of gamma secretase in class 3 of the apo- state ensemble | | Descriptor: | Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ... | | Authors: | Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5GAM
 | | Foot region of the yeast spliceosomal U4/U6.U5 tri-snRNP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ... | | Authors: | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-02-03 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
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5FN2
 | | Cryo-EM structure of gamma secretase in complex with a drug DAPT | | Descriptor: | Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ... | | Authors: | Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-04 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5FKU
 | | cryo-EM structure of the E. coli replicative DNA polymerase complex in DNA free state (DNA polymerase III alpha, beta, epsilon, tau complex) | | Descriptor: | DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ... | | Authors: | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | | Deposit date: | 2015-10-20 | | Release date: | 2015-11-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.34 Å) | | Cite: | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
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5FN3
 | | Cryo-EM structure of gamma secretase in class 1 of the apo- state ensemble | | Descriptor: | Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ... | | Authors: | Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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3J9M
 | | Structure of the human mitochondrial ribosome (class 1) | | Descriptor: | 12S rRNA, 16S rRNA, E-site tRNA, ... | | Authors: | Amunts, A, Brown, A, Toots, J, Scheres, S.H, Ramakrishnan, V. | | Deposit date: | 2015-02-08 | | Release date: | 2015-04-15 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Ribosome. The structure of the human mitochondrial ribosome.
Science, 348, 2015
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3J7R
 | | Structure of the translating mammalian ribosome-Sec61 complex | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | | Deposit date: | 2014-08-01 | | Release date: | 2014-09-03 | | Last modified: | 2019-10-30 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
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3J6B
 | | Structure of the yeast mitochondrial large ribosomal subunit | | Descriptor: | 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ... | | Authors: | Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | | Deposit date: | 2014-01-22 | | Release date: | 2014-04-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
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