6ZOY
 
 | | Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | | 登録日 | 2020-07-08 | | 公開日 | 2020-07-22 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
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7A4M
 | | Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A | | 分子名称: | FE (III) ION, Ferritin heavy chain, ZINC ION | | 著者 | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | | 登録日 | 2020-08-20 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-06-21 | | 実験手法 | ELECTRON MICROSCOPY (1.22 Å) | | 主引用文献 | Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
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7A5V
 | | CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W. | | 登録日 | 2020-08-22 | | 公開日 | 2020-11-18 | | 最終更新日 | 2020-11-25 | | 実験手法 | ELECTRON MICROSCOPY (1.7 Å) | | 主引用文献 | Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
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6ZOX
 | | Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | | 登録日 | 2020-07-08 | | 公開日 | 2020-07-22 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
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6ZP2
 | | Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | | 登録日 | 2020-07-08 | | 公開日 | 2020-07-22 | | 最終更新日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
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6ZP1
 | | Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | | 登録日 | 2020-07-08 | | 公開日 | 2020-07-22 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
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7NCJ
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7NCG
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7NCI
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7NCH
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7NCK
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7NCA
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7NRV
 | | Paired helical filament from Alzheimer's disease with PET ligand APN-1607 | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2021-03-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
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7NRQ
 | | Paired helical filament from primary age-related tauopathy brain | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2021-03-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
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7NRS
 | | Conformation 1 of straight filament from primary age-related tauopathy brain | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2021-03-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
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7NRT
 | | Conformation 2 of straight filament from primary age-related tauopathy brain | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2021-03-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
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7NRX
 | | Straight filament from Alzheimer's disease with PET ligand APN-1607 | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M. | | 登録日 | 2021-03-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
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7P68
 | | Globular glial tauopathy type 3 tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P6D
 | | Argyrophilic grain disease type 1 tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P67
 | | Globular glial tauopathy type 2 tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P6E
 | | Argyrophilic grain disease type 2 tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P6A
 | | Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P65
 | | Progressive supranuclear palsy tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P6B
 | | Limbic-predominant neuronal inclusion body 4R tauopathy type 1b tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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7P66
 | | Globular glial tauopathy type 1 tau filament | | 分子名称: | Microtubule-associated protein tau | | 著者 | Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W. | | 登録日 | 2021-07-15 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure-based classification of tauopathies.
Nature, 598, 2021
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