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PDB: 173 件

2NNF
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Structure of the sulfur carrier protein SoxY from Chlorobium limicola f thiosulfatophilum
分子名称: PHOSPHATE ION, Sulfur covalently-binding protein
著者Stout, J, Van Driessche, G, Savvides, S.N, Van Beeumen, J.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure.
Protein Sci., 16, 2007
2NNC
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Structure of the sulfur carrier protein SoxY from Chlorobium limicola f thiosulfatophilum
分子名称: CHLORIDE ION, NITROGEN MOLECULE, PHOSPHATE ION, ...
著者Stout, J, Van Driessche, G, Savvides, S.N, Van Beeumen, J.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献X-ray crystallographic analysis of the sulfur carrier protein SoxY from Chlorobium limicola f. thiosulfatophilum reveals a tetrameric structure.
Protein Sci., 16, 2007
8P8Q
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BU of 8p8q by Molmil
Recombinant Ym1 crystal structure
分子名称: ACETATE ION, Chitinase-like protein 3, GLYCEROL
著者Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Aegerter, H, Smole, U, Savvides, S.N, Lambrecht, B.N.
登録日2023-06-02
公開日2024-01-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
8P8T
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Ex vivo Ym2 crystal structure
分子名称: Chitinase-like protein 4, GLYCEROL
著者Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N.
登録日2023-06-02
公開日2024-01-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
8P8S
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Recombinant Ym2 crystal structure
分子名称: 1,2-ETHANEDIOL, Chitinase-like protein 4
著者Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, A, Savvides, S.N, Lambrecht, B.N.
登録日2023-06-02
公開日2024-01-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
8P8R
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Ex vivo Ym1 crystal structure
分子名称: 1,2-ETHANEDIOL, Chitinase-like protein 3
著者Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N.
登録日2023-06-02
公開日2024-01-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
7OX3
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BU of 7ox3 by Molmil
Fab 6D3: hIL-9 complex
分子名称: Heavy chain (Fab 6D3), Interleukin-9, Light chain (Fab 6D3), ...
著者De Vos, T, Savvides, S.N.
登録日2021-06-22
公開日2022-12-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9)
Biorxiv, 2022
2W7Q
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Structure of Pseudomonas aeruginosa LolA
分子名称: GLYCEROL, OUTER-MEMBRANE LIPOPROTEIN CARRIER PROTEIN
著者Remans, K, Pauwels, K, van Ulsen, P, Savvides, S, Decanniere, K, Cornelis, P, Tommassen, J, Van Gelder, P.
登録日2008-12-23
公開日2009-12-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Hydrophobic Surface Patches on Lola of Pseudomonas Aeruginosa are Essential for Lipoprotein Binding.
J.Mol.Biol., 401, 2010
7ZXK
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Human IL-27 in complex with neutralizing SRF388 FAb fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ...
著者Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N.
登録日2022-05-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
1TQ0
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Crystal structure of the potent anticoagulant thrombin mutant W215A/E217A in free form
分子名称: Prothrombin
著者Pineda, A.O, Chen, Z.-W, Caccia, S, Savvides, S.N, Waksman, G, Mathews, F.S, Di Cera, E.
登録日2004-06-16
公開日2004-08-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket
J.Biol.Chem., 279, 2004
1TQ7
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Crystal structure of the anticoagulant thrombin mutant W215A/E217A bound to PPACK
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Prothrombin, ...
著者Pineda, A.O, Chen, Z.-W, Caccia, S, Savvides, S.N, Waksman, G, Mathews, F.S, Di Cera, E.
登録日2004-06-16
公開日2004-08-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket
J.Biol.Chem., 279, 2004
5NQ5
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Mtb TMK crystal structure in complex with compound 1
分子名称: 5-methyl-1-[(3~{S})-1-[(3-phenoxyphenyl)methyl]piperidin-3-yl]pyrimidine-2,4-dione, Thymidylate kinase
著者Merceron, R, Song, L, Munier-Lehmann, H, Van Calenbergh, S, Savvides, S.
登録日2017-04-19
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors.
J. Med. Chem., 61, 2018
4PU8
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Shewanella oneidensis Toxin Antitoxin System Antitoxin Protein HipB Resolution 2.35
分子名称: Toxin-antitoxin system antidote transcriptional repressor Xre family
著者Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
登録日2014-03-12
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4PU3
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Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121)
分子名称: Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family
著者Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
登録日2014-03-12
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4PU5
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Shewanella oneidensis Toxin Antitoxin System Toxin Protein HipA Bound with AMPPNP and Mg
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ...
著者Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
登録日2014-03-12
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.834 Å)
主引用文献The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4PU4
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Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P21)
分子名称: Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family
著者Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
登録日2014-03-12
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.786 Å)
主引用文献The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4PU7
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Shewanella oneidensis Toxin Antitoxin System Antitoxin Protein HipB Resolution 1.85
分子名称: Toxin-antitoxin system antidote transcriptional repressor Xre family
著者Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
登録日2014-03-12
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
3UCF
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BU of 3ucf by Molmil
Crystal structure of a small-chain dehydrogenase
分子名称: Dehydrogenase
著者Buysschaert, G, Verstraete, K, Savvides, S, Vergauwen, B.
登録日2011-10-26
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Structural and biochemical characterization of an atypical short-chain dehydrogenase/reductase reveals an unusual cofactor preference.
Febs J., 280, 2013
7PNN
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mVenus released from fusion protein.
分子名称: CHLORIDE ION, mVenus
著者Bloch, Y, Savvides, S.N.
登録日2021-09-07
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献mVenus released from fusion protein.
To Be Published
3QS9
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Crystal structure of a human Flt3 ligand-receptor ternary complex
分子名称: FL cytokine receptor, SL cytokine
著者Verstraete, K, Savvides, S.N.
登録日2011-02-20
公開日2011-03-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (7.8 Å)
主引用文献Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex.
Blood, 118, 2011
3QS7
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Crystal structure of a human Flt3 ligand-receptor ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL cytokine receptor, SL cytokine
著者Verstraete, K, Savvides, S.N.
登録日2011-02-19
公開日2011-03-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex.
Blood, 118, 2011
5K1Q
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Crystal structure of oxidized Shewanella Yellow Enzyme 4 (SYE4) in complex with p-methylphenol
分子名称: FLAVIN MONONUCLEOTIDE, NAD(P)H:flavin oxidoreductase Sye4, P-CRESOL
著者Elegheert, J, Brige, A, Savvides, S.N.
登録日2016-05-18
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands.
FEBS Lett., 591, 2017
5K1M
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Crystal structure of oxidized Shewanella Yellow Enzyme 4 (SYE4) in complex with p-methoxyphenol
分子名称: 4-methoxyphenol, FLAVIN MONONUCLEOTIDE, NAD(P)H:flavin oxidoreductase Sye4
著者Elegheert, J, Brige, A, Savvides, S.N.
登録日2016-05-18
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands.
FEBS Lett., 591, 2017
5K1W
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Crystal structure of oxidized Shewanella Yellow Enzyme 4 (SYE4) in complex with trinitrophenol
分子名称: FLAVIN MONONUCLEOTIDE, NAD(P)H:flavin oxidoreductase Sye4, Octadecane, ...
著者Elegheert, J, Brige, A, Savvides, S.N.
登録日2016-05-18
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands.
FEBS Lett., 591, 2017
5K0R
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Crystal structure of reduced Shewanella Yellow Enzyme 4 (SYE4)
分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, NAD(P)H:flavin oxidoreductase Sye4, Octadecane
著者Elegheert, J, Brige, A, Savvides, S.N.
登録日2016-05-17
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands.
FEBS Lett., 591, 2017

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