Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 56 results

8RRR
DownloadVisualize
BU of 8rrr by Molmil
Alpha-synuclein amyloid fibril
Descriptor: Alpha-synuclein
Authors:Saibil, H.R, Monistrol, J.
Deposit date:2024-01-23
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly
Biorxiv, 2024
8RQM
DownloadVisualize
BU of 8rqm by Molmil
Alpha-synuclein amyloid fibrils
Descriptor: Alpha-synuclein
Authors:Saibil, H.R, Monistrol, J.
Deposit date:2024-01-18
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly
Biorxiv, 2024
4V2T
DownloadVisualize
BU of 4v2t by Molmil
Membrane embedded pleurotolysin pore with 13 fold symmetry
Descriptor: PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
Deposit date:2014-10-15
Release date:2015-02-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
6RN2
DownloadVisualize
BU of 6rn2 by Molmil
ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-05-07
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
3CS0
DownloadVisualize
BU of 3cs0 by Molmil
Crystal structure of DegP24
Descriptor: Periplasmic serine endoprotease DegP, pentapeptide
Authors:Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
Deposit date:2008-04-08
Release date:2008-05-27
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
5FMW
DownloadVisualize
BU of 5fmw by Molmil
The poly-C9 component of the Complement Membrane Attack Complex
Descriptor: POLYC9
Authors:Dudkina, N.V, Spicer, B.A, Reboul, C.F, Conroy, P.J, Lukoyanova, N, Elmlund, H, Law, R.H.P, Ekkel, S.M, Kondos, S.C, Goode, R.J.A, Ramm, G, Whisstock, J.C, Saibil, H.R, Dunstone, M.A.
Deposit date:2015-11-10
Release date:2016-02-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of the Poly-C9 Component of the Complement Membrane Attack Complex
Nat.Commun., 7, 2016
7PAG
DownloadVisualize
BU of 7pag by Molmil
The pore conformation of lymphocyte perforin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Perforin-1
Authors:Ivanova, M.E, Lukoyanova, N, Malhotra, S, Topf, M, Trapani, J.A, Voskoboinik, I, Saibil, H.R.
Deposit date:2021-07-29
Release date:2022-02-16
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The pore conformation of lymphocyte perforin.
Sci Adv, 8, 2022
7QIG
DownloadVisualize
BU of 7qig by Molmil
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Descriptor: Major prion protein
Authors:Manka, S.W, Zhang, W, Wenborn, A, Betts, J, Joiner, S, Saibil, H.R, Collinge, J, Wadsworth, J.D.F.
Deposit date:2021-12-14
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:2.7 angstrom cryo-EM structure of ex vivo RML prion fibrils.
Nat Commun, 13, 2022
5OFO
DownloadVisualize
BU of 5ofo by Molmil
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein
Descriptor: Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R.
Deposit date:2017-07-11
Release date:2017-08-16
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Sci Adv, 3, 2017
5OG1
DownloadVisualize
BU of 5og1 by Molmil
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state
Descriptor: Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R.
Deposit date:2017-07-11
Release date:2017-08-16
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Sci Adv, 3, 2017
2M5N
DownloadVisualize
BU of 2m5n by Molmil
Atomic-resolution structure of a cross-beta protofilament
Descriptor: Transthyretin
Authors:Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M.
Deposit date:2013-02-27
Release date:2013-07-17
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5K
DownloadVisualize
BU of 2m5k by Molmil
Atomic-resolution structure of a doublet cross-beta amyloid fibril
Descriptor: Transthyretin
Authors:Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M.
Deposit date:2013-02-27
Release date:2013-12-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (12.7 Å), SOLID-STATE NMR
Cite:Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5M
DownloadVisualize
BU of 2m5m by Molmil
Atomic-resolution structure of a triplet cross-beta amyloid fibril
Descriptor: Transthyretin
Authors:Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M.
Deposit date:2013-02-27
Release date:2013-12-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (12.2 Å), SOLID-STATE NMR
Cite:Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2ZLE
DownloadVisualize
BU of 2zle by Molmil
Cryo-EM structure of DegP12/OMP
Descriptor: Outer membrane protein C, Protease do
Authors:Schaefer, E, Saibil, H.R.
Deposit date:2008-04-09
Release date:2008-06-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
6RN4
DownloadVisualize
BU of 6rn4 by Molmil
ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-2B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-05-08
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
6RN3
DownloadVisualize
BU of 6rn3 by Molmil
ClpB (DWB mutant) bound to casein in presence of ATPgammaS - state WT-2A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-05-07
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
1GRU
DownloadVisualize
BU of 1gru by Molmil
SOLUTION STRUCTURE OF GROES-ADP7-GROEL-ATP7 COMPLEX BY CRYO-EM
Descriptor: GROEL, GROES
Authors:Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R.
Deposit date:2001-12-16
Release date:2002-01-28
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
1GR5
DownloadVisualize
BU of 1gr5 by Molmil
Solution Structure of apo GroEL by Cryo-Electron microscopy
Descriptor: 60 KDA CHAPERONIN
Authors:Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R.
Deposit date:2001-12-14
Release date:2002-01-28
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
4V3N
DownloadVisualize
BU of 4v3n by Molmil
Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered disulphide cross-link
Descriptor: PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
Deposit date:2014-10-20
Release date:2015-02-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4V3A
DownloadVisualize
BU of 4v3a by Molmil
Membrane bound pleurotolysin prepore (TMH1 lock) trapped with engineered disulphide cross-link
Descriptor: PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, CaradocDavies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
Deposit date:2014-10-17
Release date:2015-02-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4V3M
DownloadVisualize
BU of 4v3m by Molmil
Membrane bound pleurotolysin prepore (TMH2 helix lock) trapped with engineered disulphide cross-link
Descriptor: PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
Deposit date:2014-10-20
Release date:2015-02-18
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
2H50
DownloadVisualize
BU of 2h50 by Molmil
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Descriptor: small heat shock protein Hsp26
Authors:White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (10.8 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2H53
DownloadVisualize
BU of 2h53 by Molmil
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Descriptor: small heat shock protein Hsp26
Authors:White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
6QS8
DownloadVisualize
BU of 6qs8 by Molmil
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-2B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, MAGNESIUM ION, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-02-20
Release date:2019-07-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
6QS4
DownloadVisualize
BU of 6qs4 by Molmil
Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-02-20
Release date:2019-07-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019

 

123>

222624

數據於2024-07-17公開中

PDB statisticsPDBj update infoContact PDBjnumon