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2M5N

Atomic-resolution structure of a cross-beta protofilament

Summary for 2M5N
Entry DOI10.2210/pdb2m5n/pdb
Related2M5K 2M5M 3ZPK
NMR InformationBMRB: 19062
DescriptorTransthyretin (1 entity in total)
Functional Keywordsamyloid fibril, cross-beta structure, protein fibril
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains16
Total formula weight19173.86
Authors
Primary citationFitzpatrick, A.W.,Debelouchina, G.T.,Bayro, M.J.,Clare, D.K.,Caporini, M.A.,Bajaj, V.S.,Jaroniec, C.P.,Wang, L.,Ladizhansky, V.,Muller, S.A.,MacPhee, C.E.,Waudby, C.A.,Mott, H.R.,De Simone, A.,Knowles, T.P.,Saibil, H.R.,Vendruscolo, M.,Orlova, E.V.,Griffin, R.G.,Dobson, C.M.
Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110:5468-5473, 2013
Cited by
PubMed: 23513222
DOI: 10.1073/pnas.1219476110
PDB entries with the same primary citation
Experimental method
SOLID-STATE NMR
Structure validation

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