7QIG

Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains

Summary for 7QIG

Entry DOI	10.2210/pdb7qig/pdb
EMDB information	13989
Descriptor	Major prion protein (1 entity in total)
Functional Keywords	prion, amyloid, prp, prion protein, mouse rml scrapie strain, ex vivo prion, protein fibril
Biological source	Mus musculus (house mouse)
Total number of polymer chains	3
Total formula weight	45870.31
Authors	Manka, S.W.,Zhang, W.,Wenborn, A.,Betts, J.,Joiner, S.,Saibil, H.R.,Collinge, J.,Wadsworth, J.D.F. (deposition date: 2021-12-14, release date: 2022-07-27)
Primary citation	Manka, S.W.,Zhang, W.,Wenborn, A.,Betts, J.,Joiner, S.,Saibil, H.R.,Collinge, J.,Wadsworth, J.D.F. 2.7 angstrom cryo-EM structure of ex vivo RML prion fibrils. Nat Commun, 13:4004-4004, 2022 Cited by PubMed: 35831275 DOI: 10.1038/s41467-022-30457-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation