7QIG
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Summary for 7QIG
Entry DOI | 10.2210/pdb7qig/pdb |
EMDB information | 13989 |
Descriptor | Major prion protein (1 entity in total) |
Functional Keywords | prion, amyloid, prp, prion protein, mouse rml scrapie strain, ex vivo prion, protein fibril |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 3 |
Total formula weight | 45870.31 |
Authors | Manka, S.W.,Zhang, W.,Wenborn, A.,Betts, J.,Joiner, S.,Saibil, H.R.,Collinge, J.,Wadsworth, J.D.F. (deposition date: 2021-12-14, release date: 2022-07-27) |
Primary citation | Manka, S.W.,Zhang, W.,Wenborn, A.,Betts, J.,Joiner, S.,Saibil, H.R.,Collinge, J.,Wadsworth, J.D.F. 2.7 angstrom cryo-EM structure of ex vivo RML prion fibrils. Nat Commun, 13:4004-4004, 2022 Cited by PubMed: 35831275DOI: 10.1038/s41467-022-30457-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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