4S02
 
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, F42W, Y79A, and F123Y mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-30 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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4S0I
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79S, and 123A mutant | | 分子名称: | Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-31 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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5OEJ
 | | Structure of Tra1 subunit within the chromatin modifying complex SAGA | | 分子名称: | Tra1 subunit within the chromatin modifying complex SAGA | | 著者 | Sharov, G, Voltz, K, Durand, A, Kolesnikova, O, Papai, G, Myasnikov, A.G, Dejaegere, A, Ben-Shem, A, Schultz, P. | | 登録日 | 2017-07-07 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA.
Nat Commun, 8, 2017
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3FCT
 | | MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN | | 分子名称: | CADMIUM ION, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Romesberg, F.E, Santarsiero, B.D, Barnes, D, Yin, J, Spiller, B, Schultz, P.G, Stevens, R.C. | | 登録日 | 1999-06-13 | | 公開日 | 1999-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and kinetic evidence for strain in biological catalysis.
Biochemistry, 37, 1998
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3FCA
 | | Genetic Incorporation of a Metal-ion Chelating Amino Acid into proteins as biophysical probe | | 分子名称: | Cysteine synthase, ZINC ION | | 著者 | Wang, F, Lee, H, Spraggon, G, Schultz, P.G. | | 登録日 | 2008-11-21 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.149 Å) | | 主引用文献 | Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.
J.Am.Chem.Soc., 131, 2009
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2QMI
 | | Structure of the octameric penicillin-binding protein homologue from Pyrococcus abyssi | | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, LUTETIUM (III) ION, Pbp related beta-lactamase | | 著者 | Delfosse, V, Girard, E, Moulinier, L, Schultz, P, Mayer, C. | | 登録日 | 2007-07-16 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the archaeal pab87 peptidase reveals a novel self-compartmentalizing protease family
Plos One, 4, 2009
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1A4K
 | | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | | 分子名称: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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1T6H
 | | Crystal Structure T4 Lysozyme incorporating an unnatural amino acid p-iodo-L-phenylalanine at position 153 | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | | 著者 | Spraggon, G, Xie, J, Wang, L, Wu, N, Brock, A, Schultz, P.G. | | 登録日 | 2004-05-06 | | 公開日 | 2004-10-26 | | 最終更新日 | 2018-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.
Nat.Biotechnol., 22, 2004
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1ZH6
 | | Crystal Structure of p-acetylphenylalanine-tRNA synthetase in complex with p-acetylphenylalanine | | 分子名称: | 4-ACETYL-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | | 登録日 | 2005-04-22 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase.
J.Am.Chem.Soc., 127, 2005
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6TBM
 | | Structure of SAGA bound to TBP, including Spt8 and DUB | | 分子名称: | Polyubiquitin-B, SAGA-associated factor 11, Spt20, ... | | 著者 | Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. | | 登録日 | 2019-11-01 | | 公開日 | 2020-02-12 | | 最終更新日 | 2021-06-30 | | 実験手法 | ELECTRON MICROSCOPY (20 Å) | | 主引用文献 | Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
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3RIX
 | | 1.7A resolution structure of a firefly luciferase-Aspulvinone J inhibitor complex | | 分子名称: | (5Z)-4-hydroxy-3-[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]-5-{[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methylidene}furan-2(5H)-one, Luciferin 4-monooxygenase | | 著者 | Lovell, S, Battaile, K.P, Lopez, P.C, Auld, D.S, Schultz, P.J, MacArthur, R, Shen, M, Tamayo, G, Inglese, J, Sherman, D.H. | | 登録日 | 2011-04-14 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.
Chem.Biol., 18, 2011
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1UM4
 | | Catalytic Antibody 21H3 with hapten | | 分子名称: | (1R)-1-PHENYLETHYL 4-(ACETYLAMINO)BENZYLPHOSPHONATE, Antibody 21H3 H chain, Antibody 21H3 L chain | | 著者 | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | 登録日 | 2003-09-23 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1UM6
 | | catalytic antibody 21h3 | | 分子名称: | antibody 21h3, H chain, L chain | | 著者 | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | 登録日 | 2003-09-23 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1ZH0
 | | Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-(2-NAPHTHYL)-ALANINE, Tyrosyl-tRNA synthetase | | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | | 登録日 | 2005-04-22 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1UM5
 | | Catalytic Antibody 21H3 with alcohol substrate | | 分子名称: | 1-PHENYLETHANOL, Antibody 21H3 H chain, Antibody 21H3 L chain | | 著者 | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | | 登録日 | 2003-09-23 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
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1A4J
 | | DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | | 分子名称: | IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) | | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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3QE4
 | | An evolved aminoacyl-tRNA Synthetase with atypical polysubstrate specificity | | 分子名称: | 4-cyano-L-phenylalanine, Tyrosyl-tRNA synthetase | | 著者 | Young, D.D, Young, T.S, Jahnz, M, Ahmad, I, Spraggon, G, Schultz, P.G. | | 登録日 | 2011-01-19 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An Evolved Aminoacyl-tRNA Synthetase with Atypical Polysubstrate Specificity .
Biochemistry, 50, 2011
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2PXH
 | | Crystal structure of a bipyridylalanyl-tRNA synthetase | | 分子名称: | 3-(2,2'-BIPYRIDIN-5-YL)-L-ALANINE, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Xie, J, Schultz, P.G. | | 登録日 | 2007-05-14 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | A genetically encoded bidentate, metal-binding amino acid.
Angew.Chem.Int.Ed.Engl., 46, 2007
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6TB4
 | | Structure of SAGA bound to TBP | | 分子名称: | SAGA-associated factor 73 (Sgf73), Spt20, Subunit (17 kDa) of TFIID and SAGA complexes, ... | | 著者 | Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. | | 登録日 | 2019-10-31 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
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1U7D
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1U7X
 | | crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase specific for O-methyl-tyrosine | | 分子名称: | POTASSIUM ION, Tyrosyl-tRNA synthetase | | 著者 | Zhang, Y, Wang, L, Schultz, P.G, Wilson, I.A. | | 登録日 | 2004-08-04 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine.
Protein Sci., 14, 2005
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1KEL
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1KEM
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2PW8
 | | Crystal structure of sulfo-hirudin complexed to thrombin | | 分子名称: | Hirudin variant-1, NICKEL (II) ION, SODIUM ION, ... | | 著者 | Liu, C.C, Brustad, E, Liu, W, Schultz, P.G. | | 登録日 | 2007-05-10 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
J.Am.Chem.Soc., 129, 2007
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4ZJ1
 | | Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli : V216AcrF mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase TEM, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | | 登録日 | 2015-04-28 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112, 2015
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