4DCA
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![BU of 4dca by Molmil](/molmil-images/mine/4dca) | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, ADP-bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside phosphotransferase, MAGNESIUM ION | Authors: | Stogios, P.J, Minasov, G, Singer, A.U, Tan, K, Nocek, B, Evdokimova, E, Egorova, O, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-01-17 | Release date: | 2012-02-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, ADP-bound TO BE PUBLISHED
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4N3O
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![BU of 4n3o by Molmil](/molmil-images/mine/4n3o) | 2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni. | Descriptor: | CALCIUM ION, Putative D-glycero-D-manno-heptose 7-phosphate kinase | Authors: | Minasov, G, Wawrzak, Z, Gordon, E, Onopriyenko, O, Grimshaw, S, Kwon, K, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-10-07 | Release date: | 2013-10-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | 2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni. TO BE PUBLISHED
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2KKY
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![BU of 2kky by Molmil](/molmil-images/mine/2kky) | Solution Structure of C-terminal domain of oxidized NleG2-3 (residue 90-191) from Pathogenic E. coli O157:H7. Northeast Structural Genomics Consortium and Midwest Center for Structural Genomics target ET109A | Descriptor: | Uncharacterized protein ECs2156 | Authors: | Wu, B, Yee, A, Fares, C, Lemak, A, Semest, A, Claude, M, Singer, A, Edwards, A, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG), Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2009-06-29 | Release date: | 2009-08-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases. Plos Pathog., 6, 2010
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4DGT
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![BU of 4dgt by Molmil](/molmil-images/mine/4dgt) | Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-01-26 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of putative aminotransferase from Clostridium difficile
630 to be published
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4F0Y
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![BU of 4f0y by Molmil](/molmil-images/mine/4f0y) | Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-IG from Acinetobacter haemolyticus, apo | Descriptor: | Aminoglycoside N(6')-acetyltransferase type 1, CHLORIDE ION, GLYCEROL, ... | Authors: | Stogios, P.J, Evdokimova, E, Dong, A, Minasov, G, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes. ACS Infect Dis., 3, 2017
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7MX5
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![BU of 7mx5 by Molmil](/molmil-images/mine/7mx5) | Crystal structure of TolB from Acinetobacter baumannii | Descriptor: | Tol-Pal system protein TolB | Authors: | Stogios, P.J, Evdokimova, E, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-05-18 | Release date: | 2021-05-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Crystal structure of TolB from Acinetobacter baumannii To Be Published
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2ARZ
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![BU of 2arz by Molmil](/molmil-images/mine/2arz) | Crystal Structure of Protein of Unknown Function from Pseudomonas aeruginosa | Descriptor: | CHLORIDE ION, GLYCEROL, hypothetical protein PA4388 | Authors: | Nocek, B, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-08-22 | Release date: | 2005-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of hypothetical protein from Pseudomonas aeruginosa TO BE PUBLISHED
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2DXQ
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![BU of 2dxq by Molmil](/molmil-images/mine/2dxq) | Putative acetyltransferase from Agrobacterium tumefaciens str. C58 | Descriptor: | Acetyltransferase, PHOSPHATE ION | Authors: | Binkowski, T.A, Xu, X, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-08-30 | Release date: | 2006-09-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Putative acetyltransferase from Agrobacterium tumefaciens str. C58 To be published
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2B1Y
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![BU of 2b1y by Molmil](/molmil-images/mine/2b1y) | Crystal Structure of Protein of Unknown Function ATU1913 from Agrobacterium tumefaciens str. C58 | Descriptor: | SULFATE ION, hypothetical protein Atu1913 | Authors: | Nocek, B, Skarina, T, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-09-16 | Release date: | 2005-11-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Hypothetical Protein from Agrobacterium tumefaciens
reveals a new fold. To be Published
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2KKX
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![BU of 2kkx by Molmil](/molmil-images/mine/2kkx) | Solution Structure of C-terminal domain of reduced NleG2-3 (residues 90-191) from Pathogenic E. coli O157:H7. Northeast Structural Genomics Consortium and Midwest Center for Structural Genomics target ET109A | Descriptor: | Uncharacterized protein ECs2156 | Authors: | Wu, B, Yee, A, Fares, C, Lemak, A, Semest, A, Claude, M, Singer, A, Edwards, A, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-06-29 | Release date: | 2009-08-25 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases. Plos Pathog., 6, 2010
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2FBL
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![BU of 2fbl by Molmil](/molmil-images/mine/2fbl) | The crystal structure of the hypothetical protein NE1496 | Descriptor: | SODIUM ION, hypothetical protein NE1496 | Authors: | Lunin, V.V, Skarina, T, Onopriyenko, O, Binkowski, T.A, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of the hypothetical protein NE1496 To be Published
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4EVY
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![BU of 4evy by Molmil](/molmil-images/mine/4evy) | Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ig from Acinetobacter haemolyticus in complex with tobramycin | Descriptor: | Aminoglycoside N(6')-acetyltransferase type 1, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Minasov, G, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-04-26 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.768 Å) | Cite: | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes. ACS Infect Dis., 3, 2017
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2F96
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![BU of 2f96 by Molmil](/molmil-images/mine/2f96) | 2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T) | Descriptor: | MAGNESIUM ION, Ribonuclease T | Authors: | Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-05 | Release date: | 2006-02-14 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover. Structure, 15, 2007
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4EDP
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![BU of 4edp by Molmil](/molmil-images/mine/4edp) | 1.85 Angstrom resolution crystal structure of an ABC transporter from Clostridium perfringens ATCC 13124 | Descriptor: | ABC transporter, substrate-binding protein, ACETATE ION, ... | Authors: | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-27 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1.85 Angstrom resolution crystal structure of an ABC transporter from Clostridium perfringens ATCC 13124 To be Published
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4FEX
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![BU of 4fex by Molmil](/molmil-images/mine/4fex) | Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478 | Descriptor: | ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, KANAMYCIN A, ... | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-30 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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2FD5
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![BU of 2fd5 by Molmil](/molmil-images/mine/2fd5) | The crystal structure of a transcriptional regulator from Pseudomonas aeruginosa PAO1 | Descriptor: | transcriptional regulator | Authors: | Zhang, R, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-13 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of a transcriptional regulator from Pseudomonas aeruginosa PAO1 To be Published
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4EXL
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![BU of 4exl by Molmil](/molmil-images/mine/4exl) | Crystal structure of phosphate ABC transporter, periplasmic phosphate-binding protein PstS 1 (PBP1) from Streptococcus pneumoniae Canada MDR_19A | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Phosphate-binding protein pstS 1 | Authors: | Stogios, P.J, Wawrzak, Z, Kudritska, M, Minasov, G, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-04-30 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of phosphate ABC transporter, periplasmic phosphate-binding protein PstS 1 (PBP1) from Streptococcus pneumoniae Canada MDR_19A To be Published
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2FE7
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![BU of 2fe7 by Molmil](/molmil-images/mine/2fe7) | The crystal structure of a probable N-acetyltransferase from Pseudomonas aeruginosa | Descriptor: | probable N-acetyltransferase | Authors: | Zhang, R, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-15 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of a N-acetyltransferase from Pseudomonas aeruginosa To be Published
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2FIW
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![BU of 2fiw by Molmil](/molmil-images/mine/2fiw) | Crystal Structure of the GCN5-Related N-acetyltransferase: Aminotransferase, Class-II from Rhodopseudomonas palustris | Descriptor: | ACETYL COENZYME *A, GCN5-related N-acetyltransferase:Aminotransferase, class-II, ... | Authors: | Kim, Y, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-30 | Release date: | 2006-02-14 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of the GCN5-Related N-acetyltransferase: Aminotransferase, Class-II from Rhodopseudomonas palustris To be Published, 2006
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2IGT
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![BU of 2igt by Molmil](/molmil-images/mine/2igt) | Crystal Structure of the SAM Dependent Methyltransferase from Agrobacterium tumefaciens | Descriptor: | ACETIC ACID, FORMIC ACID, GLYCEROL, ... | Authors: | Kim, Y, Joachimiak, A, Xu, X, Gu, J, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-25 | Release date: | 2006-10-24 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal Structure of the SAM Dependent Methyltransferase from Agrobacterium tumefaciens To be Published
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2IJL
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![BU of 2ijl by Molmil](/molmil-images/mine/2ijl) | The structure of a putative ModE from Agrobacterium tumefaciens. | Descriptor: | 1,2-ETHANEDIOL, Molybdenum-binding transcriptional repressor, SULFATE ION | Authors: | Cuff, M.E, Evdokimova, E, Kudritska, M, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-29 | Release date: | 2006-10-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of a putative ModE from Agrobacterium tumefaciens. To be Published
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6MN1
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![BU of 6mn1 by Molmil](/molmil-images/mine/6mn1) | Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with gentamicin-CoA | Descriptor: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Aminoglycoside N(3)-acetyltransferase, ... | Authors: | Stogios, P.J, Skarina, T, Michalska, K, Xu, Z, Yim, V, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-10-01 | Release date: | 2018-10-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with gentamicin-CoA To Be Published
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2IG8
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![BU of 2ig8 by Molmil](/molmil-images/mine/2ig8) | Crystal structure of a Protein of Unknown Function PA3499 from Pseudomonas aeruginosa | Descriptor: | Hypothetical protein PA3499 | Authors: | Zhang, R, Xu, X, Gu, J, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-22 | Release date: | 2006-10-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of a hypothetical protein PA3499 from Pseudomonas aeruginosa To be Published
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7LGO
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![BU of 7lgo by Molmil](/molmil-images/mine/7lgo) | Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2 | Descriptor: | Non-structural protein 3 | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-01-20 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2 To Be Published
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4E0B
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![BU of 4e0b by Molmil](/molmil-images/mine/4e0b) | 2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 | Descriptor: | ACETATE ION, Malate dehydrogenase | Authors: | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-02 | Release date: | 2012-03-21 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | 2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 To be Published
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