1KR4
 
 | | Structure Genomics, Protein TM1056, cutA | | 分子名称: | Protein TM1056, cutA | | 著者 | Savchenko, A, Zhang, R, Joachimiak, A, Edwards, A, Akarina, T, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2002-01-08 | | 公開日 | 2002-08-14 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | X-ray crystal structure of CutA from Thermotoga maritima at 1.4 A resolution.
Proteins, 54, 2004
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1QW2
 | | Crystal Structure of a Protein of Unknown Function TA1206 from Thermoplasma acidophilum | | 分子名称: | conserved hypothetical protein TA1206 | | 著者 | Savchenko, A, Evdokimova, E, Kudrytska, M, Edwards, A.E, Christendat, D, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2003-08-30 | | 公開日 | 2004-03-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of a Hypothetical Protein "TA1206" from Thermoplasma acidophilum
To be Published
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1P9Q
 | | Structure of a hypothetical protein AF0491 from Archaeoglobus fulgidus | | 分子名称: | Hypothetical protein AF0491 | | 著者 | Savchenko, A, Evdokimova, E, Skarina, T, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A. | | 登録日 | 2003-05-12 | | 公開日 | 2004-06-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.
J.Biol.Chem., 280, 2005
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4KI3
 | | 1.70 Angstrom resolution crystal structure of outer-membrane lipoprotein carrier protein (lolA) from Yersinia pestis CO92 | | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Halavaty, A.S, Wawrzak, Z, Kudritska, M, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-05-01 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | 1.70 Angstrom resolution crystal structure of outer-membrane lipoprotein carrier protein (lolA) from Yersinia pestis CO92
To be Published
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1INL
 | | Crystal Structure of Spermidine Synthase from Thermotoga Maritima | | 分子名称: | Spermidine synthase | | 著者 | Korolev, S, Skarina, T, Ikeguchi, Y, Pegg, A.E, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2001-05-14 | | 公開日 | 2001-11-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor.
Nat.Struct.Biol., 9, 2002
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5SUJ
 | | Crystal structure of uncharacterized protein LPG2148 from Legionella pneumophila | | 分子名称: | Uncharacterized protein | | 著者 | Chang, C, Xu, X, Cui, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-08-03 | | 公開日 | 2016-08-17 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.356 Å) | | 主引用文献 | Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila.
Cell Rep, 23, 2018
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5HT0
 | | Crystal structure of an Antibiotic_NAT family aminoglycoside acetyltransferase HMB0038 from an uncultured soil metagenomic sample in complex with coenzyme A | | 分子名称: | Aminoglycoside acetyltransferase HMB0005, COENZYME A, SULFATE ION | | 著者 | Xu, Z, Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-01-26 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.752 Å) | | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
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4W8K
 | | Crystal structure of a putative Cas1 enzyme from Vibrio phage ICP1 | | 分子名称: | Cas1 protein, POTASSIUM ION | | 著者 | Stogios, P.J, Wawrzak, Z, Onopriyeno, O, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-08-25 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | To be published
To Be Published
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4W8I
 | | Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase | | 分子名称: | Probable sphingosine-1-phosphate lyase | | 著者 | Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-08-24 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2R9Q
 | | Crystal structure of 2'-deoxycytidine 5'-triphosphate deaminase from Agrobacterium tumefaciens | | 分子名称: | 2'-deoxycytidine 5'-triphosphate deaminase, Synthetic peptide 1, Synthetic peptide 2 | | 著者 | Zhang, R, Dong, A, Xu, X, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-09-13 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of 2'-deoxycytidine 5'-triphosphate deaminase from Agrobacterium tumefaciens.
To be Published
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2REK
 | | Crystal structure of tetR-family transcriptional regulator | | 分子名称: | ACETATE ION, Putative tetR-family transcriptional regulator | | 著者 | Dong, A, Xu, X, Gu, J, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-09-26 | | 公開日 | 2007-10-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structure of tetR-family transcriptional regulator.
To be Published
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4WJ0
 | | Structure of PH1245, a cas1 from Pyrococcus horikoshii | | 分子名称: | CHLORIDE ION, CRISPR-associated endonuclease Cas1 | | 著者 | Petit, P, Brown, G, Savchenko, A, Yakunin, A.F. | | 登録日 | 2014-09-29 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure of PH1245, a cas1 from Pyrococcus horikoshii
To Be Published
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2RFL
 | | Crystal structure of the putative phosphohistidine phosphatase SixA from Agrobacterium tumefaciens | | 分子名称: | ACETIC ACID, GLYCEROL, Putative phosphohistidine phosphatase SixA, ... | | 著者 | Kim, Y, Binkowski, T, Xu, X, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-10-01 | | 公開日 | 2007-10-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of the Putative Phosphohistidine Phosphatase SixA from
Agrobacterium tumefaciens.
To be Published
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4WRP
 | | The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 | | 分子名称: | Uncharacterized protein | | 著者 | Cuff, M.E, Evdokimova, E, Egorova, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-10-24 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1.
To Be Published
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4WZ3
 | | Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2 | | 分子名称: | E3 ubiquitin-protein ligase LubX, Ubiquitin-conjugating enzyme E2 D2 | | 著者 | Stogios, P.J, Quaile, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-11-18 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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4WZ2
 | | Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, Ile175Met mutant | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase LubX, HEXANE-1,6-DIOL | | 著者 | Stogios, P.J, Qualie, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-11-18 | | 公開日 | 2015-01-28 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (3.408 Å) | | 主引用文献 | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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4W97
 | | Structure of ketosteroid transcriptional regulator KstR2 of Mycobacterium tuberculosis | | 分子名称: | CHLORIDE ION, HTH-type transcriptional repressor KstR2, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-[(3aS,4S,7aS)-7a-methyl-1,5-bis(oxidanylidene)-2,3,3a,4,6,7-hexahydroinden-4-yl]propanethioate | | 著者 | Stogios, P.J, Evdokimova, E, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-08-27 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator of Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
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4WQK
 | | Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, apo form | | 分子名称: | 2''-aminoglycoside nucleotidyltransferase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Cox, G, Stogios, P.J, Savchenko, A, Wright, G.D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-10-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.482 Å) | | 主引用文献 | Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2)-Ia.
Mbio, 6, 2015
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4WQL
 | | Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound | | 分子名称: | 2''-aminoglycoside nucleotidyltransferase, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Cox, G, Stogios, P.J, Savchenko, A, Wright, G.D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-10-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2)-Ia.
Mbio, 6, 2015
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6HCD
 | | Structure of universal stress protein from Archaeoglobus fulgidus | | 分子名称: | ACETATE ION, CHLORIDE ION, UNIVERSAL STRESS PROTEIN, ... | | 著者 | Shumilin, I.A, Loch, J.I, Cymborowski, M, Xu, X, Edwards, A, Di Leo, R, Shabalin, I.G, Joachimiak, A, Savchenko, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2018-08-14 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional insight into the universal stress protein family.
Evol Appl, 6, 2013
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8SCD
 | | Crystal structure of sulfonamide resistance enzyme Sul3 in complex with reaction intermediate | | 分子名称: | 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, 4-AMINOBENZOIC ACID, CHLORIDE ION, ... | | 著者 | Stogios, P.J, Venkatesan, M, Michalska, K, Mesa, N, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2023-04-05 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics.
Nat Commun, 14, 2023
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8EJV
 | | The crystal structure of Pseudomonas putida PcaR in complex with succinate | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | | 著者 | Pham, C, Skarina, T, Di Leo, R, Stogios, P.J, Mahadevan, R, Savchenko, A. | | 登録日 | 2022-09-19 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | The crystal structure of Pseudomonas putida PcaR in complex with succinate
To Be Published
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8EJU
 | | The crystal structure of Pseudomonas putida PcaR | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Transcription regulatory protein (Pca regulon), ... | | 著者 | Pham, C, Skarina, T, Di Leo, R, Stogios, P.J, Mahadevan, R, Savchenko, A. | | 登録日 | 2022-09-19 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The crystal structure of Pseudomonas putida PcaR
To Be Published
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8SDC
 | | Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme | | 分子名称: | Alpha/beta hydrolase fold protein, CHLORIDE ION | | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | | 登録日 | 2023-04-06 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases.
Febs J., 290, 2023
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8SDD
 | | Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate | | 分子名称: | Alpha/beta hydrolase fold protein | | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | | 登録日 | 2023-04-06 | | 公開日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases.
Febs J., 290, 2023
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