2CJH
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1SQ1
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![BU of 1sq1 by Molmil](/molmil-images/mine/1sq1) | Crystal Structure of the Chorismate Synthase from Campylobacter jejuni, Northeast Structural Genomics Target BR19 | Descriptor: | Chorismate synthase, SULFATE ION | Authors: | Forouhar, F, Lee, I, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-03-17 | Release date: | 2004-04-06 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Chorismate Synthase from Campylobacter jejuni, Northeast Structural Genomics Target BR19 To be Published
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1SMG
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![BU of 1smg by Molmil](/molmil-images/mine/1smg) | CALCIUM-BOUND E41A MUTANT OF THE N-DOMAIN OF CHICKEN TROPONIN C, NMR, 40 STRUCTURES | Descriptor: | CALCIUM ION, TROPONIN C | Authors: | Gagne, S.M, Li, M.X, Sykes, B.D. | Deposit date: | 1997-02-04 | Release date: | 1997-08-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins. Biochemistry, 36, 1997
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1SPY
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![BU of 1spy by Molmil](/molmil-images/mine/1spy) | REGULATORY DOMAIN OF HUMAN CARDIAC TROPONIN C IN THE CALCIUM-FREE STATE, NMR, 40 STRUCTURES | Descriptor: | TROPONIN C | Authors: | Spyracopoulos, L, Li, M.X, Sia, S.K, Gagne, S.M, Chandra, M, Solaro, R.J, Sykes, B.D. | Deposit date: | 1997-07-14 | Release date: | 1998-09-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Calcium-induced structural transition in the regulatory domain of human cardiac troponin C. Biochemistry, 36, 1997
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1SND
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![BU of 1snd by Molmil](/molmil-images/mine/1snd) | STAPHYLOCOCCAL NUCLEASE DIMER CONTAINING A DELETION OF RESIDUES 114-119 COMPLEXED WITH CALCIUM CHLORIDE AND THE COMPETITIVE INHIBITOR DEOXYTHYMIDINE-3',5'-DIPHOSPHATE | Descriptor: | STAPHYLOCOCCAL NUCLEASE DIMER | Authors: | Green, S.M, Gittis, A.G, Meeker, A.K, Lattman, E.E. | Deposit date: | 1996-08-23 | Release date: | 1997-04-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | One-step evolution of a dimer from a monomeric protein. Nat.Struct.Biol., 2, 1995
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2CFG
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![BU of 2cfg by Molmil](/molmil-images/mine/2cfg) | AGAO in complex with wc4d3 (Ru-wire inhibitor, 4-carbon linker, delta enantiomer, data set 3) | Descriptor: | BIS[1H,1'H-2,2'-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1'~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM, COPPER (II) ION, GLYCEROL, ... | Authors: | Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B. | Deposit date: | 2006-02-21 | Release date: | 2007-05-01 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis. J.Am.Chem.Soc., 130, 2008
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1TE4
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![BU of 1te4 by Molmil](/molmil-images/mine/1te4) | Solution structure of MTH187. Ontario Centre for Structural Proteomics target MTH0187_1_111; Northeast Structural Genomics Target TT740 | Descriptor: | conserved protein MTH187 | Authors: | Gignac, I, Julien, O, Yee, A, Arrowsmith, C.H, Gagne, S.M, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-05-24 | Release date: | 2004-07-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | MTH187 from Methanobacterium thermoautotrophicum has three HEAT-like Repeats. J.Biomol.Nmr, 35, 2006
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1T0U
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![BU of 1t0u by Molmil](/molmil-images/mine/1t0u) | Crystal structure of E.coli uridine phosphorylase at 2.2 A resolution (Type-A Native) | Descriptor: | Uridine phosphorylase | Authors: | Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F. | Deposit date: | 2004-04-13 | Release date: | 2004-04-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium J.Mol.Biol., 337, 2004
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3ZWU
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![BU of 3zwu by Molmil](/molmil-images/mine/3zwu) | Pseudomonas fluorescens PhoX in complex with vanadate, a transition state analogue | Descriptor: | ALKALINE PHOSPHATASE PHOX, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C. | Deposit date: | 2011-08-02 | Release date: | 2012-08-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry Science, 345, 2014
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3NX4
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![BU of 3nx4 by Molmil](/molmil-images/mine/3nx4) | Crystal structure of the yhdH oxidoreductase from Salmonella enterica in complex with NADP | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative oxidoreductase | Authors: | Anderson, S.M, Wawrzak, Z, Peterson, S, Onopriyenko, O, Skarina, T, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-07-12 | Release date: | 2010-08-04 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the yhdH oxidoreductase from Salmonella enterica in complex with NADP To be Published
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3O04
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![BU of 3o04 by Molmil](/molmil-images/mine/3o04) | Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes | Descriptor: | beta-keto-acyl carrier protein synthase II | Authors: | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-07-19 | Release date: | 2010-08-04 | Last modified: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes To be Published
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4AYE
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![BU of 4aye by Molmil](/molmil-images/mine/4aye) | Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 E283AE304A mutant | Descriptor: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN | Authors: | Johnson, S, Tan, L, van der Veen, S, Caesar, J, Goicoechea De Jorge, E, Everett, R.J, Bai, X, Exley, R.M, Ward, P.N, Ruivo, N, Trivedi, K, Cumber, E, Jones, R, Newham, L, Staunton, D, Borrow, R, Pickering, M, Lea, S.M, Tang, C.M. | Deposit date: | 2012-06-20 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules. Plos Pathog., 8, 2012
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3O3F
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![BU of 3o3f by Molmil](/molmil-images/mine/3o3f) | T. maritima RNase H2 D107N in complex with nucleic acid substrate and magnesium ions | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MAGNESIUM ION, ... | Authors: | Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M. | Deposit date: | 2010-07-24 | Release date: | 2010-12-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage. Mol.Cell, 40, 2010
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4AYI
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![BU of 4ayi by Molmil](/molmil-images/mine/4ayi) | Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 3 Wild type | Descriptor: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H, LIPOPROTEIN GNA1870 CCOMPND 7 | Authors: | Johnson, S, Tan, L, van der Veen, S, Caesar, J, Goicoechea De Jorge, E, Everett, R.J, Bai, X, Exley, R.M, Ward, P.N, Ruivo, N, Trivedi, K, Cumber, E, Jones, R, Newham, L, Staunton, D, Borrow, R, Pickering, M, Lea, S.M, Tang, C.M. | Deposit date: | 2012-06-21 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules. Plos Pathog., 8, 2012
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4B0I
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![BU of 4b0i by Molmil](/molmil-images/mine/4b0i) | Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) mutant (H70N) from Pseudomonas aeruginosa in complex with 3-hydroxydecanoyl-N-acetyl cysteamine | Descriptor: | 3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, S-[2-(acetylamino)ethyl] (3R)-3-hydroxydecanethioate | Authors: | Moynie, L, McMahon, S.A, Leckie, S.M, Duthie, F.G, Koehnke, A, Naismith, J.H. | Deposit date: | 2012-07-02 | Release date: | 2012-11-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonas Aeruginosa J.Mol.Biol., 425, 2013
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4B71
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![BU of 4b71 by Molmil](/molmil-images/mine/4b71) | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | Descriptor: | (1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propan-1-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 | Authors: | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | Deposit date: | 2012-08-16 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012
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4B7O
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4AYN
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![BU of 4ayn by Molmil](/molmil-images/mine/4ayn) | Structure of the C-terminal barrel of Neisseria meningitidis FHbp Variant 2 | Descriptor: | FACTOR H-BINDING PROTEIN, SULFATE ION | Authors: | Johnson, S, Tan, L, van der Veen, S, Caesar, J, Goicoechea De Jorge, E, Everett, R.J, Bai, X, Exley, R.M, Ward, P.N, Ruivo, N, Trivedi, K, Cumber, E, Jones, R, Newham, L, Staunton, D, Borrow, R, Pickering, M, Lea, S.M, Tang, C.M. | Deposit date: | 2012-06-21 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules. Plos Pathog., 8, 2012
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4BKX
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![BU of 4bkx by Molmil](/molmil-images/mine/4bkx) | The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex | Descriptor: | ACETATE ION, HISTONE DEACETYLASE 1, METASTASIS-ASSOCIATED PROTEIN MTA1, ... | Authors: | Millard, C.J, Watson, P.J, Celardo, I, Gordiyenko, Y, Cowley, S.M, Robinson, C.V, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2013-04-30 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates. Mol.Cell, 51, 2013
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4BG9
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![BU of 4bg9 by Molmil](/molmil-images/mine/4bg9) | Apo form of a putative sugar kinase MK0840 from Methanopyrus kandleri (orthorhombic space group) | Descriptor: | ACETATE ION, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Schacherl, M, Waltersperger, S.M, Baumann, U. | Deposit date: | 2013-03-24 | Release date: | 2013-11-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Structural Characterization of the Ribonuclease H-Like Type Askha Superfamily Kinase Mk0840 from Methanopyrus Kandleri Acta Crystallogr.,Sect.D, 69, 2013
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3O8Z
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![BU of 3o8z by Molmil](/molmil-images/mine/3o8z) | Crystal structure of Spn1 (Iws1) core domain | Descriptor: | SULFATE ION, Transcription factor IWS1 | Authors: | McDonald, S.M, Close, D, Hill, C.P. | Deposit date: | 2010-08-03 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and biological importance of the spn1-spt6 interaction, and its regulatory role in nucleosome binding. Mol.Cell, 40, 2010
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4BL4
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![BU of 4bl4 by Molmil](/molmil-images/mine/4bl4) | Further structural insights into the binding of complement factor H by complement regulator acquiring surface protein 1, CspA (BbCRASP-1), of Borrelia burgdorferi. | Descriptor: | COMPLEMENT REGULATOR-ACQUIRING SURFACE PROTEIN 1 (CRASP-1) | Authors: | Caesar, J.J.E, Wallich, R, Kraiczy, P, Zipfel, P.F, Lea, S.M. | Deposit date: | 2013-05-01 | Release date: | 2013-06-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.06 Å) | Cite: | Further Structural Insights Into the Binding of Complement Factor H by Complement Regulator-Acquiring Surface Protein 1 (CspA) of Borrelia Burgdorferi. Acta Crystallogr.,Sect.F, 69, 2013
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4B6E
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![BU of 4b6e by Molmil](/molmil-images/mine/4b6e) | Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function | Descriptor: | 1H-indazol-7-amine, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, ... | Authors: | Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. | Deposit date: | 2012-08-09 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012
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4BIK
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![BU of 4bik by Molmil](/molmil-images/mine/4bik) | Structure of a disulfide locked mutant of Intermedilysin with human CD59 | Descriptor: | CD59 GLYCOPROTEIN, INTERMEDILYSIN | Authors: | Johnson, S, Brooks, N.J, Smith, R.A.G, Lea, S.M, Bubeck, D. | Deposit date: | 2013-04-10 | Release date: | 2013-05-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.494 Å) | Cite: | Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59 Cell Rep., 3, 2013
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4BA9
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![BU of 4ba9 by Molmil](/molmil-images/mine/4ba9) | The structural basis for the coordination of Y-family Translesion DNA Polymerases by Rev1 | Descriptor: | DNA POLYMERASE KAPPA, DNA REPAIR PROTEIN REV1, MAGNESIUM ION, ... | Authors: | Grummitt, C.G, Kilkenny, M.L, Frey, A, Roe, S.M, Oliver, A.W, Sale, J.E, Pearl, L.H. | Deposit date: | 2012-09-12 | Release date: | 2013-09-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | The Structural Basis for the Coordination of Y- Family Translesion DNA Polymerases by Rev1 To be Published
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