2WW4
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![BU of 2ww4 by Molmil](/molmil-images/mine/2ww4) | a triclinic crystal form of E. coli 4-diphosphocytidyl-2C-methyl-D- erythritol kinase | Descriptor: | 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL | Authors: | Kalinowska-Tluscik, J, Miallau, L, Gabrielsen, M, Leonard, G.A, McSweeney, S.M, Hunter, W.N. | Deposit date: | 2009-10-21 | Release date: | 2010-03-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Triclinic Crystal Form of Escherichia Coli 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase and Reassessment of the Quaternary Structure. Acta Crystallogr.,Sect.F, 66, 2010
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1HEJ
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![BU of 1hej by Molmil](/molmil-images/mine/1hej) | C-terminal xylan binding domain from Cellulomonas fimi xylanase 11A | Descriptor: | ENDO-1,4-BETA-XYLANASE D | Authors: | Simpson, P.J, Hefang, X, Bolam, D.N, White, P, Hancock, S.M, Gilbert, H.J, Williamson, M.P. | Deposit date: | 2000-11-22 | Release date: | 2001-05-10 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A Biochemistry, 40, 2001
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3T60
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![BU of 3t60 by Molmil](/molmil-images/mine/3t60) | 5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase | Descriptor: | 2',5'-dideoxy-5'-(tritylamino)uridine, Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative, ... | Authors: | Hampton, S.E, Baragana, B, Schipani, A, Bosch-Navarrete, C, Musso-Buendia, A, Recio, E, Kaiser, M, Whittingham, J.L, Roberts, S.M, Shevtsov, M, Brannigan, J.A, Kahnberg, P, Brun, R, Wilson, K.S, Gonzalez-Pacanowska, D, Johansson, N.G, Gilbert, I.H. | Deposit date: | 2011-07-28 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. Chemmedchem, 6, 2011
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1HEH
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![BU of 1heh by Molmil](/molmil-images/mine/1heh) | C-terminal xylan binding domain from Cellulomonas fimi xylanase 11A | Descriptor: | ENDO-1,4-BETA-XYLANASE D | Authors: | Simpson, P.J, Hefang, X, Bolam, D.N, White, P, Hancock, S.M, Gilbert, H.J, Williamson, M.P. | Deposit date: | 2000-11-22 | Release date: | 2001-05-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A Biochemistry, 40, 2001
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1H8T
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![BU of 1h8t by Molmil](/molmil-images/mine/1h8t) | Echovirus 11 | Descriptor: | 12-AMINO-DODECANOIC ACID, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... | Authors: | Stuart, A, McKee, T, Williams, P.A, Harley, C, Stuart, D.I, Brown, T.D.K, Lea, S.M. | Deposit date: | 2001-02-15 | Release date: | 2002-07-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection J.Virol., 76, 2002
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1H8F
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![BU of 1h8f by Molmil](/molmil-images/mine/1h8f) | Glycogen Synthase Kinase 3 beta. | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Dajani, R, Pearl, L.H, Roe, S.M. | Deposit date: | 2001-02-05 | Release date: | 2002-01-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Glycogen Synthase Kinase 3Beta . Structural Basis for Phosphate-Primed Substrate Specificity and Autoinhibition Cell(Cambridge,Mass.), 105, 2001
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1GS0
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![BU of 1gs0 by Molmil](/molmil-images/mine/1gs0) | |
3T64
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![BU of 3t64 by Molmil](/molmil-images/mine/3t64) | 5'-Diphenyl Nucleoside Inhibitors of Plasmodium falciparum dUTPase | Descriptor: | 2',5'-dideoxy-5'-[(diphenylmethyl)amino]uridine, 5'-(BENZHYDRYLAMINO)-2',5'-DIDEOXYURIDINE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Hampton, S.E, Baragana, B, Schipani, A, Bosch-Navarrete, C, Musso-Buendia, A, Recio, E, Kaiser, M, Whittingham, J.L, Roberts, S.M, Shevtsov, M, Brannigan, J.A, Kahnberg, P, Brun, R, Wilson, K.S, Gonzalez-Pacanowska, D, Johansson, N.G, Gilbert, I.H. | Deposit date: | 2011-07-28 | Release date: | 2012-08-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. Chemmedchem, 6, 2011
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6UZT
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![BU of 6uzt by Molmil](/molmil-images/mine/6uzt) | Crystal Structure of RPTP alpha | Descriptor: | Receptor-type tyrosine-protein phosphatase alpha | Authors: | Santelli, E, Wen, Y, Yang, S, Svensson, M.N.D, Stanford, S.M, Bottini, N. | Deposit date: | 2019-11-15 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | RPTP alpha phosphatase activity is allosterically regulated by the membrane-distal catalytic domain. J.Biol.Chem., 295, 2020
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5FPX
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![BU of 5fpx by Molmil](/molmil-images/mine/5fpx) | The structure of KdgF from Yersinia enterocolitica. | Descriptor: | NICKEL (II) ION, PECTIN DEGRADATION PROTEIN, PEPTIDE | Authors: | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | Deposit date: | 2015-12-03 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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3C37
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![BU of 3c37 by Molmil](/molmil-images/mine/3c37) | X-ray structure of the putative Zn-dependent peptidase Q74D82 at the resolution 1.7 A. Northeast Structural Genomics Consortium target GsR143A | Descriptor: | DI(HYDROXYETHYL)ETHER, Peptidase, M48 family, ... | Authors: | Kuzin, A.P, Chen, Y, Seetharaman, J, Vorobiev, S.M, Forouhar, F, Wang, D, Mao, L, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-01-27 | Release date: | 2008-02-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | X-ray structure of the putative Zn-dependent peptidase Q74D82 at the resolution 1.7 A. To be Published
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2VVK
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![BU of 2vvk by Molmil](/molmil-images/mine/2vvk) | Grb2 SH3C (1) | Descriptor: | GLYCEROL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 | Authors: | Harkiolaki, M, Tsirka, T, Feller, S.M. | Deposit date: | 2008-06-09 | Release date: | 2009-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2. Structure, 17, 2009
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5FQ0
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![BU of 5fq0 by Molmil](/molmil-images/mine/5fq0) | The structure of KdgF from Halomonas sp. | Descriptor: | CITRATE ANION, KDGF, NICKEL (II) ION, ... | Authors: | Hobbs, J.K, Lee, S.M, Robb, M, Hof, F, Barr, C, Abe, K.T, Hehemann, J.H, McLean, R, Abbott, D.W, Boraston, A.B. | Deposit date: | 2015-12-03 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kdgf, the Missing Link in the Microbial Metabolism of Uronate Sugars from Pectin and Alginate. Proc.Natl.Acad.Sci.USA, 113, 2016
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1FST
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![BU of 1fst by Molmil](/molmil-images/mine/1fst) | CRYSTAL STRUCTURE OF TRUNCATED HUMAN RHOGDI TRIPLE MUTANT | Descriptor: | RHO GDP-DISSOCIATION INHIBITOR 1 | Authors: | Longenecker, K.L, Garrard, S.M, Sheffield, P.J, Derewenda, Z.S. | Deposit date: | 2000-09-11 | Release date: | 2001-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI. Acta Crystallogr.,Sect.D, 57, 2001
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6SLH
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![BU of 6slh by Molmil](/molmil-images/mine/6slh) | Conformational flexibility within the small domain of human serine racemase. | Descriptor: | MAGNESIUM ION, SODIUM ION, Serine racemase, ... | Authors: | Koulouris, C.R, Bax, B, Atack, J, Roe, S.M. | Deposit date: | 2019-08-19 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Conformational flexibility within the small domain of human serine racemase. Acta Crystallogr.,Sect.F, 76, 2020
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2X04
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![BU of 2x04 by Molmil](/molmil-images/mine/2x04) | Crystal structure of the PABC-TNRC6C complex | Descriptor: | POLYADENYLATE-BINDING PROTEIN 1, SULFATE ION, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN | Authors: | Jinek, M, Fabian, M.R, Coyle, S.M, Sonenberg, N, Doudna, J.A. | Deposit date: | 2009-12-04 | Release date: | 2010-01-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation Nat.Struct.Mol.Biol., 17, 2010
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5FDB
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![BU of 5fdb by Molmil](/molmil-images/mine/5fdb) | |
2WYN
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![BU of 2wyn by Molmil](/molmil-images/mine/2wyn) | Structure of family 37 trehalase from Escherichia coli in complex with a casuarine-6-O-a-D-glucoside analogue | Descriptor: | (1R,2R,3R,6R,7R,7AR)-3,7-BIS(HYDROXYMETHYL)HEXAHYDRO-1H-PYRROLIZINE-1,2,6-TRIOL, CALCIUM ION, PERIPLASMIC TREHALASE, ... | Authors: | Gloster, T.M, Roberts, S.M, Davies, G.J, Cardona, F, Goti, A, Parmeggiani, C, Parenti, P, Fusi, P, Forcella, M, Cipolla, L. | Deposit date: | 2009-11-17 | Release date: | 2010-09-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Casuarine-6-O-alpha-D-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases. Chem.Commun.(Camb.), 46, 2010
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3UT0
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![BU of 3ut0 by Molmil](/molmil-images/mine/3ut0) | Crystal structure of exo-1,3/1,4-beta-glucanase (EXOP) from Pseudoalteromonas sp. BB1 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Exo-1,3/1,4-beta-glucanase, ... | Authors: | Nakatani, Y, Cutfield, S.M, Cutfield, J.F. | Deposit date: | 2011-11-24 | Release date: | 2011-12-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and activity of exo-1,3/1,4-beta-glucanase from marine bacterium Pseudoalteromonas sp. BB1 showing a novel C-terminal domain Febs J., 2011
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5FYG
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![BU of 5fyg by Molmil](/molmil-images/mine/5fyg) | Structure of CYP153A from Marinobacter aquaeolei in complex with hydroxydodecanoic acid | Descriptor: | 12-HYDROXYDODECANOIC ACID, CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Danesh-Azari, H.-R, Spandolf, C, Hoffman, S.M, Weissenborn, M, Hauer, B, Grogan, G. | Deposit date: | 2016-03-07 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure-Guided Redesign of CYP153AM.aqfor the Improved Terminal Hydroxylation of Fatty Acids Chemcatchem, 2016
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3D5N
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![BU of 3d5n by Molmil](/molmil-images/mine/3d5n) | Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125. | Descriptor: | Q97W15_SULSO | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Lee, D, Foote, R.E, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-05-16 | Release date: | 2008-07-15 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the Q97W15_SULSO protein from Sulfolobus solfataricus. NESG target SsR125. To be Published
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6UST
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![BU of 6ust by Molmil](/molmil-images/mine/6ust) | Gut microbial sulfatase from Hungatella hathewayi | Descriptor: | CALCIUM ION, N-acetylgalactosamine 6-sulfate sulfatase | Authors: | Ervin, S.M, Redinbo, M.R. | Deposit date: | 2019-10-28 | Release date: | 2020-11-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Insights into Endobiotic Reactivation by Human Gut Microbiome-Encoded Sulfatases. Biochemistry, 59, 2020
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7NPI
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![BU of 7npi by Molmil](/molmil-images/mine/7npi) | Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5) | Descriptor: | CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ... | Authors: | Lange, S.M, Armstrong, L.A, Kulathu, Y. | Deposit date: | 2021-02-26 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
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5FJI
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![BU of 5fji by Molmil](/molmil-images/mine/5fji) | Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-GLUCOSIDASE, ... | Authors: | Agirre, J, Ariza, A, Offen, W.A, Turkenburg, J.P, Roberts, S.M, McNicholas, S, Harris, P.V, McBrayer, B, Dohnalek, J, Cowtan, K.D, Davies, G.J, Wilson, K.S. | Deposit date: | 2015-10-09 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Three-Dimensional Structures of Two Heavily N-Glycosylated Aspergillus Sp. Family Gh3 Beta-D-Glucosidases Acta Crystallogr.,Sect.D, 72, 2016
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2XRC
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![BU of 2xrc by Molmil](/molmil-images/mine/2xrc) | Human complement factor I | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HUMAN COMPLEMENT FACTOR I | Authors: | Roversi, P, Johnson, S, Lea, S.M. | Deposit date: | 2010-09-13 | Release date: | 2011-07-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms. Proc.Natl.Acad.Sci.USA, 108, 2011
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