6UZT

Crystal Structure of RPTP alpha

Summary for 6UZT

Entry DOI	10.2210/pdb6uzt/pdb
Descriptor	Receptor-type tyrosine-protein phosphatase alpha (2 entities in total)
Functional Keywords	protein tyrosine phosphatase, enzyme, hydrolase, alpha/beta protein, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	139220.27
Authors	Santelli, E.,Wen, Y.,Yang, S.,Svensson, M.N.D.,Stanford, S.M.,Bottini, N. (deposition date: 2019-11-15, release date: 2020-03-18, Last modification date: 2023-10-11)
Primary citation	Wen, Y.,Yang, S.,Wakabayashi, K.,Svensson, M.N.D.,Stanford, S.M.,Santelli, E.,Bottini, N. RPTP alpha phosphatase activity is allosterically regulated by the membrane-distal catalytic domain. J.Biol.Chem., 295:4923-4936, 2020 Cited by PubMed: 32139509 DOI: 10.1074/jbc.RA119.011808 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation