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PDB: 2585 件

1P7J
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Crystal structure of engrailed homeodomain mutant K52E
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed
著者Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F.
登録日2003-05-02
公開日2003-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
1P8T
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BU of 1p8t by Molmil
Crystal structure of Nogo-66 Receptor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Reticulon 4 receptor
著者Barton, W.A, Liu, B.P, Tzvetkova, D, Jeffrey, P.D, Fournier, A.E, Sah, D, Cate, R, Strittmatter, S.M, Nikolov, D.B.
登録日2003-05-07
公開日2003-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins
Embo J., 22, 2003
4DXD
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BU of 4dxd by Molmil
Staphylococcal Aureus FtsZ in complex with 723
分子名称: 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
著者Lu, J, Soisson, S.M.
登録日2012-02-27
公開日2012-05-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics.
Sci Transl Med, 4, 2012
4E3F
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Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
分子名称: 2,6-DIHYDROXYBENZOIC ACID, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ...
著者Cohen, S.M, Martin, D.P.
登録日2012-03-09
公開日2012-06-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
1QFK
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BU of 1qfk by Molmil
STRUCTURE OF HUMAN FACTOR VIIA AND ITS IMPLICATIONS FOR THE TRIGGERING OF BLOOD COAGULATION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COAGULATION FACTOR VIIA HEAVY CHAIN, ...
著者Pike, A.C.W, Brzozowski, A.M, Roberts, S.M, Olsen, O.H, Persson, E.
登録日1999-04-12
公開日1999-08-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human factor VIIa and its implications for the triggering of blood coagulation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1Q7C
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BU of 1q7c by Molmil
The structure of betaketoacyl-[ACP] reductase Y151F mutant in complex with NADPH fragment
分子名称: 3-oxoacyl-[acyl-carrier protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Price, A.C, Zhang, Y.-M, Rock, C.O, White, S.M.
登録日2003-08-17
公開日2004-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cofactor-Induced Conformational Rearrangements Establish a Catalytically Competent Active Site and a Proton Relay Conduit in FabG
Structure, 12, 2004
3CPK
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BU of 3cpk by Molmil
Crystal structure of the Q7W7N7_BORPA protein from Bordetella parapertussis. Northeast Structural Genomics Consortium target BeR31
分子名称: Uncharacterized protein Q7W7N7_BORPA
著者Vorobiev, S.M, Abashidze, M, Seetharaman, J, Zhao, L, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-03-31
公開日2008-04-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the Q7W7N7_BORPA protein from Bordetella parapertussis.
To be Published
3CQ9
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BU of 3cq9 by Molmil
Crystal structure of the lp_1622 protein from Lactobacillus plantarum. Northeast Structural Genomics Consortium target LpR114
分子名称: SULFATE ION, Uncharacterized protein lp_1622
著者Vorobiev, S.M, Abashidze, M, Seetharaman, J, Zhao, L, Maglaqui, M, Foote, E.L, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-04-02
公開日2008-04-15
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the lp_1622 protein from Lactobacillus plantarum.
To be Published
3DAS
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BU of 3das by Molmil
Structure of the PQQ-bound form of Aldose Sugar Dehydrogenase (Adh) from Streptomyces coelicolor
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PYRROLOQUINOLINE QUINONE, ...
著者Southall, S.M, Doel, J.J, Oubrie, A, Richardson, D.J.
登録日2008-05-30
公開日2009-06-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Enzymatic Characterization of a Thermostable PQQ-dependent Soluble Aldose Sugar Dehydrogenase
To be Published
1Q9P
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Solution structure of the mature HIV-1 protease monomer
分子名称: HIV-1 Protease
著者Ishima, R, Torchia, D.A, Lynch, S.M, Gronenborn, A.M, Louis, J.M.
登録日2003-08-25
公開日2004-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the mature HIV-1 protease monomer: Insight into the tertiary fold and stability of a precursor
J.Biol.Chem., 278, 2003
2LUV
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BU of 2luv by Molmil
Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
分子名称: Integrin alpha-X
著者Chua, G.L, Tang, X, Patra, T.A, Tan, S.M, Bhattacharjya, S.
登録日2012-06-21
公開日2012-07-04
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
To be Published
3DC7
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BU of 3dc7 by Molmil
Crystal structure of the protein Q88SR8 from Lactobacillus plantarum. Northeast Structural Genomics consortium target LpR109.
分子名称: MAGNESIUM ION, Putative uncharacterized protein lp_3323, SODIUM ION, ...
著者Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Seetharaman, J, Zhao, L, Mao, L, Ciccosanti, C, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-03
公開日2008-08-05
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure of the protein Q88SR8 from Lactobacillus plantarum. Northeast Structural Genomics consortium target LpR109. (CASP Target)
To be Published
4F91
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Brr2 Helicase Region
分子名称: U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C.
登録日2012-05-18
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
1A4H
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BU of 1a4h by Molmil
STRUCTURE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE IN COMPLEX WITH GELDANAMYCIN
分子名称: GELDANAMYCIN, HEAT SHOCK PROTEIN 90
著者Prodromou, C, Roe, S.M, Pearl, L.H.
登録日1998-01-29
公開日1998-08-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
Cell(Cambridge,Mass.), 90, 1997
5VBE
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BU of 5vbe by Molmil
Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GDP
分子名称: 1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gentile, D.R, Jenkins, M.L, Moss, S.M, Burke, J.E, Shokat, K.M.
登録日2017-03-29
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Cell Chem Biol, 24, 2017
1A93
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NMR SOLUTION STRUCTURE OF THE C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: MAX PROTEIN, MYC PROTO-ONCOGENE PROTEIN
著者Lavigne, P, Crump, M.P, Gagne, S.M, Hodges, R.S, Kay, C.M, Sykes, B.D.
登録日1998-04-15
公開日1998-10-21
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.
J.Mol.Biol., 281, 1998
4IMO
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BU of 4imo by Molmil
Crystal structure of wild type human Lipocalin PGDS in complex with substrate analog U44069
分子名称: (5E)-7-{(1R,4S,5S,6R)-5-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl}hept-5-enoic acid, Lipocalin-type prostaglandin-D synthase, THIOCYANATE ION
著者Lim, S.M, Chen, D, Teo, H, Roos, A, Nyman, T, Tresaugues, L, Pervushin, K, Nordlund, P.
登録日2013-01-03
公開日2013-03-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase.
J.Lipid Res., 54, 2013
1QO0
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BU of 1qo0 by Molmil
Amide receptor of the amidase operon of Pseudomonas aeruginosa (AmiC) complexed with the negative regulator AmiR.
分子名称: AMIC, AMIR, BUTYRAMIDE
著者Pearl, L.H, O'Hara, B.P, Roe, S.M.
登録日1999-10-26
公開日1999-12-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure and Induction Mechanism of Amic-Amir: A Ligand-Regulated Transcription Antitermination Complex
Embo J., 18, 1999
1QNL
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AMIDE RECEPTOR/NEGATIVE REGULATOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH BUTYRAMIDE
分子名称: ALIPHATIC AMIDASE EXPRESSION-REGULATING PROTEIN, BUTYRAMIDE
著者Pearl, L.H, O'Hara, B.P, Roe, S.M.
登録日1999-10-19
公開日1999-12-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Adaptation to Selective Pressure for Altered Ligand Specificity in the Pseudomonas Aeruginosa Amide Receptor, Amic
Protein Eng., 13, 2000
3DCP
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Crystal structure of the putative histidinol phosphatase hisK from Listeria monocytogenes. Northeast Structural Genomics Consortium target LmR141.
分子名称: FE (III) ION, Histidinol-phosphatase, ZINC ION
著者Vorobiev, S.M, Su, M, Seetharaman, J, Zhao, L, Mao, L, Foote, E.L, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-04
公開日2008-07-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the putative histidinol phosphatase hisK from Listeria monocytogenes.
To be Published
4FDN
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BU of 4fdn by Molmil
Mycobacterium tuberculosis DprE1 in complex with CT325 - hexagonal crystal form
分子名称: 3-(hydroxyamino)-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, FLAVIN-ADENINE DINUCLEOTIDE, oxidoreductase DprE1
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-29
公開日2012-07-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
1AIJ
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PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES IN THE CHARGE-NEUTRAL DQAQB STATE
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ...
著者Stowell, M.H.B, Mcphillips, T.M, Soltis, S.M, Rees, D.C, Abresch, E, Feher, G.
登録日1997-04-18
公開日1997-10-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer.
Science, 276, 1997
1RE1
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BU of 1re1 by Molmil
CRYSTAL STRUCTURE OF CASPASE-3 WITH A NICOTINIC ACID ALDEHYDE INHIBITOR
分子名称: (3S)-3-{[(5-BROMOPYRIDIN-3-YL)CARBONYL]AMINO}-4-OXOBUTANOIC ACID, Caspase-3
著者Becker, J.W, Rotonda, J, Soisson, S.M.
登録日2003-11-06
公開日2004-05-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis
J.Med.Chem., 47, 2004
1R2X
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BU of 1r2x by Molmil
Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
分子名称: 50S ribosomal protein L11, 58nts of 23S rRNA
著者Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
登録日2003-09-30
公開日2003-11-04
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
3C96
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Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase
著者Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-02-15
公開日2008-02-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa.
To be Published

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件を2024-11-06に公開中

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