4F91
Brr2 Helicase Region
Summary for 4F91
| Entry DOI | 10.2210/pdb4f91/pdb |
| Related | 4F92 4F93 |
| Descriptor | U5 small nuclear ribonucleoprotein 200 kDa helicase (2 entities in total) |
| Functional Keywords | rnp remodeling, pre-mrna splicing, spliceosome catalytic activation, dexd/h-box rna helicase, rna and atp binding, nucleus, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: O75643 |
| Total number of polymer chains | 1 |
| Total formula weight | 197238.23 |
| Authors | Santos, K.F.,Jovin, S.M.,Weber, G.,Pena, V.,Luehrmann, R.,Wahl, M.C. (deposition date: 2012-05-18, release date: 2012-10-17, Last modification date: 2024-02-28) |
| Primary citation | Santos, K.F.,Jovin, S.M.,Weber, G.,Pena, V.,Luhrmann, R.,Wahl, M.C. Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109:17418-17423, 2012 Cited by PubMed: 23045696DOI: 10.1073/pnas.1208098109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.697 Å) |
Structure validation
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