7U6Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u6z by Molmil](/molmil-images/mine/7u6z) | Pertussis toxin E129D NAD | Descriptor: | IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin subunit 1 | Authors: | Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J. | Deposit date: | 2022-03-06 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.30002 Å) | Cite: | Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity. J.Biol.Chem., 298, 2022
|
|
1S9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s9y by Molmil](/molmil-images/mine/1s9y) | Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQS, in complex with HLA-A2 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W. | Deposit date: | 2004-02-05 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279, 2004
|
|
1S9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s9x by Molmil](/molmil-images/mine/1s9x) | Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQA, in complex with HLA-A2 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W. | Deposit date: | 2004-02-05 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279, 2004
|
|
1S9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s9w by Molmil](/molmil-images/mine/1s9w) | Crystal Structure Analysis of NY-ESO-1 epitope, SLLMWITQC, in complex with HLA-A2 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W. | Deposit date: | 2004-02-05 | Release date: | 2004-09-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue J.Biol.Chem., 279, 2004
|
|
6MRA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mra by Molmil](/molmil-images/mine/6mra) | Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies | Descriptor: | TCR alpha chain, TCR beta-chain | Authors: | Sundararaj, S, Le Nours, J, Praveena, T, Rossjohn, J. | Deposit date: | 2018-10-12 | Release date: | 2019-09-18 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nat Commun, 10, 2019
|
|
1YN6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yn6 by Molmil](/molmil-images/mine/1yn6) | Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase | Descriptor: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | Deposit date: | 2005-01-23 | Release date: | 2005-06-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
|
|
1YZW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yzw by Molmil](/molmil-images/mine/1yzw) | The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore | Descriptor: | DI(HYDROXYETHYL)ETHER, GFP-like non-fluorescent chromoprotein | Authors: | Wilmann, P.G, Petersen, J, Pettikiriarachchi, A, Buckle, A.M, Devenish, R.J, Prescott, M, Rossjohn, J. | Deposit date: | 2005-02-28 | Release date: | 2005-05-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore J.Mol.Biol., 349, 2005
|
|
4WNQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wnq by Molmil](/molmil-images/mine/4wnq) | THE MOLECULAR BASES OF DELTA/ALPHA-BETA T-CELL MEDIATED ANTIGEN RECOGNITION | Descriptor: | TCR Variable Beta 2 (TRBV20) chain and TCR constant Beta chain, TCR Variable Delta 1 chain and TCR constant Alpha chain | Authors: | Pellicci, D.G, Uldrich, A.P, Le Nours, J, Ross, F, Chabrol, E, Eckle, S.B.G, de Boer, R, Lim, R.T, McPherson, K, Besra, G, Howell, A.R, Moretta, L, McCluskey, J, Heemskerk, M.H.M, Gras, S, Rossjohn, J, Godfrey, D.I. | Deposit date: | 2014-10-14 | Release date: | 2014-11-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The molecular bases of delta / alpha beta T cell-mediated antigen recognition. J.Exp.Med., 211, 2014
|
|
4WO4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wo4 by Molmil](/molmil-images/mine/4wo4) | The molecular bases of Delta/Alpha beta T cell-mediated antigen recognition. | Descriptor: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pellicci, D.G, Uldrich, A.P, Le Nours, J, Ross, F, Chabrol, E, Eckle, S.B.G, de Boer, R, Lim, R.T, McPherson, K, Besra, G, Howell, A.R, Moretta, L, McCluskey, J, Heemskerk, M.H.M, Gras, S, Rossjohn, J, Godfrey, D.I. | Deposit date: | 2014-10-15 | Release date: | 2014-11-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The molecular bases of delta / alpha beta T cell-mediated antigen recognition. J.Exp.Med., 211, 2014
|
|
1YDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ydp by Molmil](/molmil-images/mine/1ydp) | 1.9A crystal structure of HLA-G | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, COBALT (II) ION, ... | Authors: | Clements, C.S, Kjer-nielsen, L, Kostenko, L, Hoare, H.L, Dunstone, M.A, Moses, E, Freed, K, Brooks, A.G, Rossjohn, J, Mccluskey, J. | Deposit date: | 2004-12-25 | Release date: | 2005-03-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal-maternal interface PROC.NATL.ACAD.SCI.USA, 102, 2005
|
|
1SYV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1syv by Molmil](/molmil-images/mine/1syv) | HLA-B*4405 complexed to the dominant self ligand EEFGRAYGF | Descriptor: | Beta-2-microglobulin, MHC class I antigen, major histocompatibility complex, ... | Authors: | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | Deposit date: | 2004-04-02 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion J.Exp.Med., 200, 2004
|
|
6NUX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nux by Molmil](/molmil-images/mine/6nux) | CD1a-lipid binary complex | Descriptor: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | Authors: | Wegrecki, M, Le Nours, J, Rossjohn, J. | Deposit date: | 2019-02-03 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Sci Immunol, 5, 2020
|
|
1ZHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zhk by Molmil](/molmil-images/mine/1zhk) | Crystal structure of HLA-B*3501 presenting 13-mer EBV antigen LPEPLPQGQLTAY | Descriptor: | Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ... | Authors: | Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J. | Deposit date: | 2005-04-26 | Release date: | 2005-05-17 | Last modified: | 2014-04-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance J.Biol.Chem., 280, 2005
|
|
4Z7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z7u by Molmil](/molmil-images/mine/4z7u) | S13 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, ... | Authors: | Petersen, J, Rossjohn, J, Reid, H.H, Koning, F. | Deposit date: | 2015-04-08 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Determinants of Gliadin-Specific T Cell Selection in Celiac Disease. J Immunol., 194, 2015
|
|
4Z7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z7w by Molmil](/molmil-images/mine/4z7w) | T316 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQ8-glia-alpha1, MHC class II HLA-DQ-alpha chain, ... | Authors: | Petersen, J, Rossjohn, J, Reid, H.H, Koning, F. | Deposit date: | 2015-04-08 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Determinants of Gliadin-Specific T Cell Selection in Celiac Disease. J Immunol., 194, 2015
|
|
1SY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sy6 by Molmil](/molmil-images/mine/1sy6) | Crystal Structure of CD3gammaepsilon Heterodimer in Complex with OKT3 Fab Fragment | Descriptor: | OKT3 Fab heavy chain, OKT3 Fab light chain, T-cell surface glycoprotein CD3 gamma/epsilon chain | Authors: | Kjer-Nielsen, L, Dunstone, M.A, Kostenko, L, Ely, L.K, Beddoe, T, Misfud, N.A, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J. | Deposit date: | 2004-03-31 | Release date: | 2004-05-25 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the human T cell receptor CD3(epsilon)(gamma) heterodimer complexed to the therapeutic mAb OKT3. Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1ZSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zsd by Molmil](/molmil-images/mine/1zsd) | Crystal Structure Of HLA-B*3501 Presenting an 11-Mer EBV Antigen EPLPQGQLTAY | Descriptor: | BZLF1 trans-activator protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Miles, J.J, Elhassen, D, Borg, N.A, Silins, S.L, Tynan, F.E, Burrows, J.M, Purcell, A.W, Kjer-Nielsen, L, Rossjohn, J, Burrows, S.R, McCluskey, J. | Deposit date: | 2005-05-24 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CTL Recognition of a Bulged Viral Peptide Involves Biased TCR Selection. J.Immunol., 175, 2005
|
|
1SYS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sys by Molmil](/molmil-images/mine/1sys) | Crystal structure of HLA, B*4403, and peptide EEPTVIKKY | Descriptor: | Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule | Authors: | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | Deposit date: | 2004-04-01 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion J.Exp.Med., 200, 2004
|
|
1T0M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t0m by Molmil](/molmil-images/mine/1t0m) | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | Descriptor: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | Authors: | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | Deposit date: | 2004-04-12 | Release date: | 2004-11-23 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173, 2004
|
|
4Z7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z7v by Molmil](/molmil-images/mine/4z7v) | L3-12 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, ... | Authors: | Petersen, J, Rossjohn, J, Reid, H.H, Koning, F. | Deposit date: | 2015-04-08 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Determinants of Gliadin-Specific T Cell Selection in Celiac Disease. J Immunol., 194, 2015
|
|
1YN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yn7 by Molmil](/molmil-images/mine/1yn7) | Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase | Descriptor: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | Deposit date: | 2005-01-24 | Release date: | 2005-06-28 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
|
|
1T0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t0n by Molmil](/molmil-images/mine/1t0n) | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | Descriptor: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | Authors: | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | Deposit date: | 2004-04-12 | Release date: | 2004-11-23 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol., 173, 2004
|
|
1ZHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zhl by Molmil](/molmil-images/mine/1zhl) | Crystal structure of HLA-B*3508 presenting 13-mer EBV antigen LPEPLPQGQLTAY | Descriptor: | Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ... | Authors: | Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J. | Deposit date: | 2005-04-26 | Release date: | 2005-05-17 | Last modified: | 2014-04-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance J.Biol.Chem., 280, 2005
|
|
4Y1A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y1a by Molmil](/molmil-images/mine/4y1a) | immune complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FS17_alpha, FS17_beta, ... | Authors: | Beringer, D.X, Vivian, J.P, Reid, H.H, Rossjohn, J. | Deposit date: | 2015-02-07 | Release date: | 2015-09-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nat.Immunol., 16, 2015
|
|
4G8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g8i by Molmil](/molmil-images/mine/4g8i) | Crystal Structure of HLA B2705-KK10-L6M | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Gag protein, ... | Authors: | Gras, S, Wilmann, P.G, Rossjohn, J. | Deposit date: | 2012-07-23 | Release date: | 2013-03-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
|
|