7U6Z

Pertussis toxin E129D NAD

Summary for 7U6Z

Entry DOI	10.2210/pdb7u6z/pdb
Related	7SKI 7SKK 7SKY 7SNE
Descriptor	Pertussis toxin subunit 1, IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	toxin, adp-ribosyltransferase, transferase, whooping cough, inhibitor, pertussis
Biological source	Bordetella pertussis
Total number of polymer chains	2
Total formula weight	43035.45
Authors	Littler, D.R.,Beddoe, T.,Pulliainen, A.,Rossjohn, J. (deposition date: 2022-03-06, release date: 2022-04-13, Last modification date: 2023-10-18)
Primary citation	Sakari, M.,Tran, M.T.,Rossjohn, J.,Pulliainen, A.T.,Beddoe, T.,Littler, D.R. Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity. J.Biol.Chem., 298:101892-101892, 2022 Cited by PubMed: 35378130 DOI: 10.1016/j.jbc.2022.101892 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.30001992416 Å)

Structure validation