7U6Z
 
 | | Pertussis toxin E129D NAD | | 分子名称: | IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin subunit 1 | | 著者 | Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J. | | 登録日 | 2022-03-06 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.30002 Å) | | 主引用文献 | Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
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6C15
 | | CD1c in complex with phosphatidylcholine | | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Wun, K.S, Rossjohn, J. | | 登録日 | 2018-01-03 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Nat. Immunol., 19, 2018
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6W9Q
 | | Peptide-bound SARS-CoV-2 Nsp9 RNA-replicase | | 分子名称: | 3C-like proteinase peptide, Non-structural protein 9 fusion, PHOSPHATE ION | | 著者 | Littler, D.R, Gully, B.S, Riboldi-Tunnicliffe, A, Rossjohn, J. | | 登録日 | 2020-03-23 | | 公開日 | 2020-04-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9.
Iscience, 23, 2020
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3DX7
 | | Crystal Structure of HLA-B*4403 presenting 10mer EBV antigen | | 分子名称: | ACETATE ION, Beta-2-microglobulin, EBV decapeptide epitope, ... | | 著者 | Archbold, J.K, Ely, L.K, Rossjohn, J. | | 登録日 | 2008-07-23 | | 公開日 | 2009-01-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
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6VMX
 | | Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Farenc, C, Rossjohn, J, Gras, S. | | 登録日 | 2020-01-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals.
J Immunol., 205, 2020
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3SPV
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3ARG
 | | Ternary crystal structure of the mouse NKT TCR-CD1d-alpha-glucosylceramide(C20:2) | | 分子名称: | (11E,14E)-N-[(2S,3S,4R)-1-(alpha-D-glucopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wun, K.S, Rossjohn, J. | | 登録日 | 2010-11-27 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells
Immunity, 34, 2011
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3AU1
 | | Crystal structure of mouse CD1d in complex with ganglioside GD3 | | 分子名称: | (7Z,15E,17E)-N-[(2S,3S,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tricosa-7,15,17-trienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Roisman, L.C, Rossjohn, J. | | 登録日 | 2011-01-28 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A molecular basis for NKT cell recognition of CD1d-self-antigen
Immunity, 34, 2011
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3ARB
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3ARD
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3FQR
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3FQU
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3ARF
 | | Ternary crystal structure of the mouse NKT TCR-CD1d-C20:2 | | 分子名称: | (11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Wun, K.S, Rossjohn, J. | | 登録日 | 2010-11-27 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells
Immunity, 34, 2011
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3FQN
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3ARE
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6C09
 | | Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex | | 分子名称: | (2R)-2,3-dihydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wun, K.S, Rossjohn, J. | | 登録日 | 2017-12-28 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Nat. Immunol., 19, 2018
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6V7Z
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6V2Q
 | | HLA-B*57:03 presenting the peptide LSSPVTKSF | | 分子名称: | ACETATE ION, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ... | | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | | 登録日 | 2019-11-25 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
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3FQX
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4ZY7
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3DX9
 | | Crystal Structure of the DM1 TCR at 2.75A | | 分子名称: | DM1 T cell receptor alpha chain, DM1 T cell receptor beta chain | | 著者 | Archbold, J.K, Macdonald, W.A, Gras, S, Rossjohn, J. | | 登録日 | 2008-07-24 | | 公開日 | 2009-01-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
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6WC1
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5V4M
 | | Structure of HLA-DR15 with bound alpha3(135-145) peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ... | | 著者 | Petersen, J, Rossjohn, J. | | 登録日 | 2017-03-10 | | 公開日 | 2017-05-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
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3FQW
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3FQT
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