8TNJ
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![BU of 8tnj by Molmil](/molmil-images/mine/8tnj) | Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs | Descriptor: | 9mer peptide,Beta-2-microglobulin,MHC class I antigen chimera, B.1 Fab heavy chain, B.1 Fab light chain, ... | Authors: | Ross, P, Adams, E.J, Lodwick, J, Zhao, M, Slezak, T, Kossiakoff, A. | Deposit date: | 2023-08-02 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs To Be Published
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4UCG
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![BU of 4ucg by Molmil](/molmil-images/mine/4ucg) | NmeDAH7PS R126S variant | Descriptor: | DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, ... | Authors: | Cross, P.J, Heyes, L.C, Zhang, S, Nazmi, A.R, Parker, E.J. | Deposit date: | 2014-12-03 | Release date: | 2016-01-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Functional Unit of Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase is Dimeric. Plos One, 11, 2016
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2M89
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![BU of 2m89 by Molmil](/molmil-images/mine/2m89) | Solution structure of the Aha1 dimer from Colwellia psychrerythraea | Descriptor: | Aha1 domain protein | Authors: | Rossi, P, Sgourakis, N.G, Shi, L, Liu, G, Barbieri, C.M, Lee, H, Grant, T.D, Luft, J.R, Xiao, R, Acton, T.B, Montelione, G.T, Snell, E.H, Baker, D, Lange, O.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-05-09 | Release date: | 2013-09-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta. Proteins, 83, 2015
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3PG9
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![BU of 3pg9 by Molmil](/molmil-images/mine/3pg9) | Thermotoga maritima DAH7P synthase in complex with inhibitor | Descriptor: | AZIDE ION, CHLORIDE ION, NITRATE ION, ... | Authors: | Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J. | Deposit date: | 2010-10-31 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis J.Biol.Chem., 286, 2011
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3PG8
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![BU of 3pg8 by Molmil](/molmil-images/mine/3pg8) | Truncated form of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Thermotoga maritima | Descriptor: | AZIDE ION, GLYCEROL, Phospho-2-dehydro-3-deoxyheptonate aldolase | Authors: | Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J. | Deposit date: | 2010-10-31 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis J.Biol.Chem., 286, 2011
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4HSO
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![BU of 4hso by Molmil](/molmil-images/mine/4hso) | Crystal structure of S213G variant DAH7PS from Neisseria meningitidis | Descriptor: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... | Authors: | Cross, P.J, Pietersma, A.L, Allison, T.M, Wilson-Coutts, S.M, Cochrane, F.C, Parker, E.J. | Deposit date: | 2012-10-30 | Release date: | 2013-09-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine. Protein Sci., 22, 2013
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4HSN
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![BU of 4hsn by Molmil](/molmil-images/mine/4hsn) | Crystal structure of DAH7PS from Neisseria meningitidis | Descriptor: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... | Authors: | Cross, P.J, Pietersma, A.L, Allison, T.M, Wilson-Coutts, S.M, Cochrane, F.C, Parker, E.J. | Deposit date: | 2012-10-30 | Release date: | 2013-09-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine. Protein Sci., 22, 2013
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1YEZ
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![BU of 1yez by Molmil](/molmil-images/mine/1yez) | Solution structure of the conserved protein from the gene locus MM1357 of Methanosarcina mazei. Northeast Structural Genomics target MaR30. | Descriptor: | MM1357 | Authors: | Rossi, P, Aramini, J.M, Swapna, G.V.T, Huang, Y.P, Xiao, R, Ho, C.K, Ma, L.C, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-12-29 | Release date: | 2005-02-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the conserved protein from the gene locus MM1357 of Methanosarcina mazei. Northeast Structural Genomics target MaR30. To be Published
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4IXX
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![BU of 4ixx by Molmil](/molmil-images/mine/4ixx) | Crystal structure of S213G variant DAH7PS without Tyr bound from Neisseria meningitidis | Descriptor: | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, SULFATE ION | Authors: | Cross, P.J, Pietersma, A.L, Allison, T.M, Wilson-Coutts, S.M, Cochrane, F.C, Parker, E.J. | Deposit date: | 2013-01-28 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine. Protein Sci., 22, 2013
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7MZZ
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7MZW
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![BU of 7mzw by Molmil](/molmil-images/mine/7mzw) | |
7MZX
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4GRS
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![BU of 4grs by Molmil](/molmil-images/mine/4grs) | Crystal structure of a chimeric DAH7PS | Descriptor: | Phospho-2-dehydro-3-deoxyheptonate aldolase, 2-dehydro-3-deoxyphosphoheptonate aldolase, TYROSINE | Authors: | Cross, P.J, Allison, T.M, Dobson, R.C.J, Jameson, G.B, Parker, E.J. | Deposit date: | 2012-08-26 | Release date: | 2013-02-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain Proc.Natl.Acad.Sci.USA, 110, 2013
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6C58
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6C5A
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6C5Z
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![BU of 6c5z by Molmil](/molmil-images/mine/6c5z) | Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-glucose and NADH bound | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Gross, P.G, Sidlo, A.M, Walsh, R.M, Peeples, W.B, Wood, Z.A. | Deposit date: | 2018-01-17 | Release date: | 2019-01-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | The A225L Substitution of hUGDH alters structure and function To Be Published
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2MV0
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![BU of 2mv0 by Molmil](/molmil-images/mine/2mv0) | Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690 | Descriptor: | Maltose-binding periplasmic protein | Authors: | Rossi, P, Lange, O.F, Sgourakis, N.G, Song, Y, Lee, H, Aramini, J.M, Ertekin, A, Xiao, R, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2014-09-18 | Release date: | 2014-12-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
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2EXN
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![BU of 2exn by Molmil](/molmil-images/mine/2exn) | Solution structure for the protein coded by gene locus BB0938 of Bordetella bronchiseptica. Northeast Structural Genomics target BoR11. | Descriptor: | Hypothetical protein BoR11 | Authors: | Rossi, P, Ramelot, T, Xiao, R, Ho, C.K, Ma, L.-C, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-11-08 | Release date: | 2005-11-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | (1)H, (13)C, and (15)N Resonance Assignments for the Protein Coded by Gene Locus BB0938 of Bordetella bronchiseptica J.Biomol.NMR, 33, 2005
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2FJ6
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![BU of 2fj6 by Molmil](/molmil-images/mine/2fj6) | Solution NMR structure of the UPF0346 protein yozE from Bacillus subtilis. Northeast Structural Genomics target SR391. | Descriptor: | Hypothetical UPF0346 protein yozE | Authors: | Rossi, P, Acton, T.B, Cunningham, K.E, Ma, L.C, Shetty, K, Swapna, G.V.T, Xiao, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-12-31 | Release date: | 2006-02-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the UPF0346 protein yozE from Bacillus subtilis. Northeast Structural Genomics target SR391. To be Published
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2LTT
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![BU of 2ltt by Molmil](/molmil-images/mine/2ltt) | Solution NMR Structure of YdbC:dT19G1 complex. Northeast Structural Genomics Consortium (NESG) Target KR150 | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Putative uncharacterized protein ydbC | Authors: | Rossi, P, Barbieri, C.M, Aramini, J.A, Bini, E, Lee, H, Janjua, H, Ciccosanti, C, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-31 | Release date: | 2012-06-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome. Nucleic Acids Res., 41, 2013
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2JXP
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![BU of 2jxp by Molmil](/molmil-images/mine/2jxp) | Solution NMR structure of uncharacterized lipoprotein B from Nitrosomonas europaea. Northeast Structural Genomics target NeR45A | Descriptor: | Putative lipoprotein B | Authors: | Rossi, P, Wang, D, Janjua, H, Owens, L, Xiao, R, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-11-27 | Release date: | 2007-12-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of uncharacterized lipoprotein B from Nitrosomonas europaea. To be Published
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2K3A
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![BU of 2k3a by Molmil](/molmil-images/mine/2k3a) | NMR solution structure of Staphylococcus saprophyticus CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain protein. Northeast Structural Genomics Consortium target SyR11 | Descriptor: | CHAP domain protein | Authors: | Rossi, P, Aramini, J.M, Chen, C.X, Nwosu, C, Cunningham, K.C, Owens, L.A, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-04-29 | Release date: | 2008-05-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus. Proteins, 74, 2008
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2JN0
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![BU of 2jn0 by Molmil](/molmil-images/mine/2jn0) | Solution NMR structure of the ygdR protein from Escherichia coli. Northeast Structural Genomics target ER382A. | Descriptor: | Hypothetical lipoprotein ygdR | Authors: | Rossi, P, Chen, C.X, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J.C, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-12-15 | Release date: | 2007-05-01 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the ygdR protein from Escherichia coli. Northeast Structural Genomics target ER382A. To be Published
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2KCX
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2KKQ
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![BU of 2kkq by Molmil](/molmil-images/mine/2kkq) | Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158. | Descriptor: | Myotilin | Authors: | Rossi, P, Shastry, R, Ciccosanti, C, Hamilton, K, Xiao, R, Acton, T.B, Swapna, G.V.T, Nair, R, Everett, J.K, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-29 | Release date: | 2009-07-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158. To be Published
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