4HSN

Crystal structure of DAH7PS from Neisseria meningitidis

Summary for 4HSN

Entry DOI	10.2210/pdb4hsn/pdb
Related	4HSO
Descriptor	3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	dahp, dahps, dah7ps, tim barrel, transferase, allosteric regulation, aromatic biosynthesis, shikimate pathway
Biological source	Neisseria meningitidis
Total number of polymer chains	4
Total formula weight	156124.70
Authors	Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J. (deposition date: 2012-10-30, release date: 2013-09-11, Last modification date: 2023-09-20)
Primary citation	Cross, P.J.,Pietersma, A.L.,Allison, T.M.,Wilson-Coutts, S.M.,Cochrane, F.C.,Parker, E.J. Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine. Protein Sci., 22:1087-1099, 2013 Cited by PubMed: 23754471 DOI: 10.1002/pro.2293 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation