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PDB: 146 件

8TNJ
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Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs
分子名称: 9mer peptide,Beta-2-microglobulin,MHC class I antigen chimera, B.1 Fab heavy chain, B.1 Fab light chain, ...
著者Ross, P, Adams, E.J, Lodwick, J, Zhao, M, Slezak, T, Kossiakoff, A.
登録日2023-08-02
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs
To Be Published
4UCG
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NmeDAH7PS R126S variant
分子名称: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, ...
著者Cross, P.J, Heyes, L.C, Zhang, S, Nazmi, A.R, Parker, E.J.
登録日2014-12-03
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Functional Unit of Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase is Dimeric.
Plos One, 11, 2016
2M89
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Solution structure of the Aha1 dimer from Colwellia psychrerythraea
分子名称: Aha1 domain protein
著者Rossi, P, Sgourakis, N.G, Shi, L, Liu, G, Barbieri, C.M, Lee, H, Grant, T.D, Luft, J.R, Xiao, R, Acton, T.B, Montelione, G.T, Snell, E.H, Baker, D, Lange, O.A, Northeast Structural Genomics Consortium (NESG)
登録日2013-05-09
公開日2013-09-04
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta.
Proteins, 83, 2015
3PG9
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Thermotoga maritima DAH7P synthase in complex with inhibitor
分子名称: AZIDE ION, CHLORIDE ION, NITRATE ION, ...
著者Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J.
登録日2010-10-31
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
3PG8
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Truncated form of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Thermotoga maritima
分子名称: AZIDE ION, GLYCEROL, Phospho-2-dehydro-3-deoxyheptonate aldolase
著者Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J.
登録日2010-10-31
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
4HSO
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Crystal structure of S213G variant DAH7PS from Neisseria meningitidis
分子名称: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
著者Cross, P.J, Pietersma, A.L, Allison, T.M, Wilson-Coutts, S.M, Cochrane, F.C, Parker, E.J.
登録日2012-10-30
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
Protein Sci., 22, 2013
4HSN
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Crystal structure of DAH7PS from Neisseria meningitidis
分子名称: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
著者Cross, P.J, Pietersma, A.L, Allison, T.M, Wilson-Coutts, S.M, Cochrane, F.C, Parker, E.J.
登録日2012-10-30
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
Protein Sci., 22, 2013
1YEZ
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Solution structure of the conserved protein from the gene locus MM1357 of Methanosarcina mazei. Northeast Structural Genomics target MaR30.
分子名称: MM1357
著者Rossi, P, Aramini, J.M, Swapna, G.V.T, Huang, Y.P, Xiao, R, Ho, C.K, Ma, L.C, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2004-12-29
公開日2005-02-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the conserved protein from the gene locus MM1357 of Methanosarcina mazei. Northeast Structural Genomics target MaR30.
To be Published
4IXX
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BU of 4ixx by Molmil
Crystal structure of S213G variant DAH7PS without Tyr bound from Neisseria meningitidis
分子名称: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, MANGANESE (II) ION, SULFATE ION
著者Cross, P.J, Pietersma, A.L, Allison, T.M, Wilson-Coutts, S.M, Cochrane, F.C, Parker, E.J.
登録日2013-01-28
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
Protein Sci., 22, 2013
7MZZ
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AUGbeta - FAM150A - ALKL1 60-128
分子名称: ALK and LTK ligand 1
著者Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日2021-05-24
公開日2021-11-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZW
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Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025
分子名称: ALK tyrosine kinase receptor
著者Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日2021-05-24
公開日2021-12-08
最終更新日2021-12-15
実験手法SOLUTION NMR
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZX
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AUGalpha - FAM150B - ALKL2 77-152
分子名称: ALK and LTK ligand 2
著者Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日2021-05-24
公開日2021-11-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
4GRS
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BU of 4grs by Molmil
Crystal structure of a chimeric DAH7PS
分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, 2-dehydro-3-deoxyphosphoheptonate aldolase, TYROSINE
著者Cross, P.J, Allison, T.M, Dobson, R.C.J, Jameson, G.B, Parker, E.J.
登録日2012-08-26
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain
Proc.Natl.Acad.Sci.USA, 110, 2013
6C58
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Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-xylose bound
分子名称: CHLORIDE ION, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE
著者Gross, P.G, Fallah, J, Wood, Z.A.
登録日2018-01-15
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献The A225L Substitution of hUGDH alters structure and function
To Be Published
6C5A
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Human UDP-Glucose Dehydrogenase with UDP- Glc and NADH bound
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, UDP-glucose 6-dehydrogenase, ...
著者Gross, P.G, Fallah, J, Wood, Z.A.
登録日2018-01-15
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The A225L Substitution of hUGDH alters structure and function
To Be Published
6C5Z
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BU of 6c5z by Molmil
Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-glucose and NADH bound
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Gross, P.G, Sidlo, A.M, Walsh, R.M, Peeples, W.B, Wood, Z.A.
登録日2018-01-17
公開日2019-01-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The A225L Substitution of hUGDH alters structure and function
To Be Published
2MV0
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BU of 2mv0 by Molmil
Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690
分子名称: Maltose-binding periplasmic protein
著者Rossi, P, Lange, O.F, Sgourakis, N.G, Song, Y, Lee, H, Aramini, J.M, Ertekin, A, Xiao, R, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2014-09-18
公開日2014-12-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.
Proc.Natl.Acad.Sci.USA, 109, 2012
2EXN
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BU of 2exn by Molmil
Solution structure for the protein coded by gene locus BB0938 of Bordetella bronchiseptica. Northeast Structural Genomics target BoR11.
分子名称: Hypothetical protein BoR11
著者Rossi, P, Ramelot, T, Xiao, R, Ho, C.K, Ma, L.-C, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2005-11-08
公開日2005-11-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献(1)H, (13)C, and (15)N Resonance Assignments for the Protein Coded by Gene Locus BB0938 of Bordetella bronchiseptica
J.Biomol.NMR, 33, 2005
2FJ6
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BU of 2fj6 by Molmil
Solution NMR structure of the UPF0346 protein yozE from Bacillus subtilis. Northeast Structural Genomics target SR391.
分子名称: Hypothetical UPF0346 protein yozE
著者Rossi, P, Acton, T.B, Cunningham, K.E, Ma, L.C, Shetty, K, Swapna, G.V.T, Xiao, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2005-12-31
公開日2006-02-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the UPF0346 protein yozE from Bacillus subtilis. Northeast Structural Genomics target SR391.
To be Published
2LTT
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BU of 2ltt by Molmil
Solution NMR Structure of YdbC:dT19G1 complex. Northeast Structural Genomics Consortium (NESG) Target KR150
分子名称: DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Putative uncharacterized protein ydbC
著者Rossi, P, Barbieri, C.M, Aramini, J.A, Bini, E, Lee, H, Janjua, H, Ciccosanti, C, Wang, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2012-05-31
公開日2012-06-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome.
Nucleic Acids Res., 41, 2013
2JXP
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BU of 2jxp by Molmil
Solution NMR structure of uncharacterized lipoprotein B from Nitrosomonas europaea. Northeast Structural Genomics target NeR45A
分子名称: Putative lipoprotein B
著者Rossi, P, Wang, D, Janjua, H, Owens, L, Xiao, R, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-11-27
公開日2007-12-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution NMR structure of uncharacterized lipoprotein B from Nitrosomonas europaea.
To be Published
2K3A
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BU of 2k3a by Molmil
NMR solution structure of Staphylococcus saprophyticus CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain protein. Northeast Structural Genomics Consortium target SyR11
分子名称: CHAP domain protein
著者Rossi, P, Aramini, J.M, Chen, C.X, Nwosu, C, Cunningham, K.C, Owens, L.A, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-04-29
公開日2008-05-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Proteins, 74, 2008
2JN0
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BU of 2jn0 by Molmil
Solution NMR structure of the ygdR protein from Escherichia coli. Northeast Structural Genomics target ER382A.
分子名称: Hypothetical lipoprotein ygdR
著者Rossi, P, Chen, C.X, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J.C, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-15
公開日2007-05-01
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the ygdR protein from Escherichia coli. Northeast Structural Genomics target ER382A.
To be Published
2KCX
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Solution NMR Structure of Kazal-1 Domain of Human Follistatin-related protein 3 (FSTL-3). Northeast Structural Genomics Target HR6186A.
分子名称: Follistatin-related protein 3
著者Rossi, P, Chiang, Y, Anderson, S, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-12-30
公開日2009-03-10
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Kazal-1 Domain of Human Follistatin-related protein 3 (FSTL-3). Northeast Structural Genomics Target HR6186A.
To be Published
2KKQ
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Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158.
分子名称: Myotilin
著者Rossi, P, Shastry, R, Ciccosanti, C, Hamilton, K, Xiao, R, Acton, T.B, Swapna, G.V.T, Nair, R, Everett, J.K, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-06-29
公開日2009-07-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158.
To be Published

223790

件を2024-08-14に公開中

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