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PDB: 22 件
4ZG4
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Myosin Vc Pre-powerstroke
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ropars, V, Pylypenko, O, Sweeney, L, Houdusse, A.
登録日2015-04-22
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Force-producing ADP state of myosin bound to actin.
Proc.Natl.Acad.Sci.USA, 113, 2016
3Q4F
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Crystal structure of xrcc4/xlf-cernunnos complex
分子名称: DNA repair protein XRCC4, Non-homologous end-joining factor 1
著者Ropars, V, Legrand, P, Charbonnier, J.B.
登録日2010-12-23
公開日2011-08-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Proc.Natl.Acad.Sci.USA, 108, 2011
5HMP
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BU of 5hmp by Molmil
Myosin Vc pre-powerstroke state
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ...
著者Ropars, V, Pylypenko, O, Sweeney, H.L, Houdusse, A.
登録日2016-01-16
公開日2016-09-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献The myosin X motor is optimized for movement on actin bundles.
Nat Commun, 7, 2016
5HMO
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myosin X motor activity
分子名称: Unconventional myosin-X
著者Ropars, V, Blanc, F, Samazan, F, Houdusse, A.
登録日2016-01-16
公開日2016-09-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.493 Å)
主引用文献The myosin X motor is optimized for movement on actin bundles.
Nat Commun, 7, 2016
8CJ3
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Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone
分子名称: Histone chaperone ASF1A, c3u_7 chimera inhibitor of histone chaperone ASF1
著者Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
登録日2023-02-11
公開日2023-07-05
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ2
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Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone
分子名称: GLYCEROL, Histone chaperone ASF1A, SULFATE ION, ...
著者Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
登録日2023-02-11
公開日2023-07-05
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.127 Å)
主引用文献Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ1
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Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone
分子名称: Histone chaperone ASF1A, c3u_3 chimera inhibitor of histone chaperone ASF1
著者Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
登録日2023-02-11
公開日2023-07-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.564 Å)
主引用文献Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
6RMN
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DNA mismatch repair proteins MLH1 and MLH3
分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION
著者Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2019-05-07
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ABM
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X-ray structure of phosphorylated Barrier-to-autointegration factor (BAF)
分子名称: Barrier-to-autointegration factor, CESIUM ION
著者Zinn-Justin, S, Marcelot, A, Le Du, M.H, Ropars, V.
登録日2020-09-08
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.
Nucleic Acids Res., 49, 2021
6GY2
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Crystal structure of human Plk1-PBD in complex with WSSSLATPPTLSSpTVLI phosphopeptide from BRCA2
分子名称: GLYCEROL, Phosphopeptide of BRCA2, Serine/threonine-protein kinase PLK1
著者Miron, S, Ropars, V, Zinn-Justin, S.
登録日2018-06-28
公開日2019-07-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1.
Nat Commun, 11, 2020
4ANJ
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MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4)
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ...
著者Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M.
登録日2012-03-19
公開日2012-10-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi.
Mol.Cell, 48, 2012
6SHX
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BU of 6shx by Molmil
DNA mismatch repair proteins MLH1 and MLH3
分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION
著者Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2019-08-08
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
6SNS
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BU of 6sns by Molmil
DNA mismatch repair proteins MLH1 and MLH3
分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION
著者Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2019-08-27
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
6SNV
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BU of 6snv by Molmil
DNA mismatch repair proteins MLH1 and MLH3
分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION
著者Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2019-08-27
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
6GHD
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BU of 6ghd by Molmil
Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases
分子名称: 1,2-ETHANEDIOL, Barrier-to-autointegration factor, Emerin, ...
著者Samson, C, Petitalot, A, Celli, F, Herrada, I, Ropars, V, Ledu, M.H, Nhiri, N, Arteni, A.A, Buendia, B, ZinnJustin, S.
登録日2018-05-07
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
Nucleic Acids Res., 46, 2018
6ERG
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BU of 6erg by Molmil
Complex of XLF and heterodimer Ku bound to DNA
分子名称: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
著者Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2017-10-18
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERH
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BU of 6erh by Molmil
Complex of XLF and heterodimer Ku bound to DNA
分子名称: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
著者Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2017-10-18
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERF
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Complex of APLF factor and Ku heterodimer bound to DNA
分子名称: Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ...
著者Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2017-10-18
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat.Struct.Mol.Biol., 25, 2018
8A50
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Crystal structure of HSF2BP-ALPHA1 tetramer
分子名称: Heat shock factor 2-binding protein, PHOSPHATE ION
著者Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S.
登録日2022-06-13
公開日2023-07-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.484 Å)
主引用文献BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Sci Adv, 9, 2023
8A51
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Crystal structure of HSF2BP-BRME1 complex
分子名称: 1,2-ETHANEDIOL, Break repair meiotic recombinase recruitment factor 1, CHLORIDE ION, ...
著者Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S.
登録日2022-06-13
公開日2023-07-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Sci Adv, 9, 2023
8ASC
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Ku70/80 binds to the Ku-binding motif of PAXX
分子名称: DNA (5'-D(P*CP*GP*GP*AP*TP*CP*GP*AP*GP*GP*GP*CP*CP*CP*GP*AP*TP*AP*T)-3'), DNA (5'-D(P*GP*GP*GP*CP*CP*CP*TP*CP*GP*AP*TP*CP*CP*G)-3'), Protein PAXX, ...
著者Seif El Dahan, M, Ropars, V, Charbonnier, J.B.
登録日2022-08-19
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
8BV1
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Peptide inhibitor P4 in complex with ASF1 histone chaperone
分子名称: GLYCEROL, Histone chaperone ASF1A, P4 peptide inhibitor of histone chaperone ASF1
著者Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
登録日2022-12-01
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.834 Å)
主引用文献Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023

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