5W0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w0s by Molmil](/molmil-images/mine/5w0s) | GroEL using cryoEM | Descriptor: | 60 kDa chaperonin | Authors: | Roh, S.H, Chiu, W. | Deposit date: | 2017-05-31 | Release date: | 2017-08-09 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6M0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m0r by Molmil](/molmil-images/mine/6m0r) | 2.7A Yeast Vo state3 | Descriptor: | (6~{E},10~{E},14~{E},18~{E},22~{E},26~{E},30~{R})-2,6,10,14,18,22,26,30-octamethyldotriaconta-2,6,10,14,18,22,26-heptaene, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, PYROPHOSPHATE, ... | Authors: | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, Singharoy, A, Chiu, W. | Deposit date: | 2020-02-22 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex. Sci Adv, 6, 2020
|
|
8IB8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ib8 by Molmil](/molmil-images/mine/8ib8) | Human TRiC-PhLP2A-actin complex in the closed state | Descriptor: | ACTB protein (Fragment), Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-09 | Release date: | 2023-12-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.42 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8I9Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i9q by Molmil](/molmil-images/mine/8i9q) | The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state | Descriptor: | Phosducin-like protein 3, T-complex protein 1 subunit delta | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-07 | Release date: | 2023-12-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
6M0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m0s by Molmil](/molmil-images/mine/6m0s) | 3.6A Yeast Vo state3 prime | Descriptor: | Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, vacuolar isoform, ... | Authors: | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, SIngharoy, A, Chiu, W. | Deposit date: | 2020-02-22 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex. Sci Adv, 6, 2020
|
|
6C6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6c6l by Molmil](/molmil-images/mine/6c6l) | Yeast Vacuolar ATPase Vo in lipid nanodisc | Descriptor: | V-type proton ATPase subunit a, vacuolar isoform, V-type proton ATPase subunit c, ... | Authors: | Roh, S, Stam, N.J, Hryc, C, Couoh-Cardel, S, Pintilie, G, Chiu, W, Wilkens, S. | Deposit date: | 2018-01-19 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The 3.5- angstrom CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase VoProton Channel. Mol. Cell, 69, 2018
|
|
7E5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e5z by Molmil](/molmil-images/mine/7e5z) | Dehydrogenase holoenzyme | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | Authors: | Roh, S.H, Park, J.S, Heo, Y.Y. | Deposit date: | 2021-02-21 | Release date: | 2022-02-23 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Dehydrogenase holoenzyme To Be Published
|
|
8I9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i9u by Molmil](/molmil-images/mine/8i9u) | Human TRiC-PhLP2A complex in the open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-02-07 | Release date: | 2024-01-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8I1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i1u by Molmil](/molmil-images/mine/8i1u) | Human TRiC-PhLP2A complex in the closed state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-01-13 | Release date: | 2024-01-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
8I6J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i6j by Molmil](/molmil-images/mine/8i6j) | The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit gamma | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | Deposit date: | 2023-01-28 | Release date: | 2024-01-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle. Nat Commun, 15, 2024
|
|
4WFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wfh by Molmil](/molmil-images/mine/4wfh) | |
4WFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wfg by Molmil](/molmil-images/mine/4wfg) | Human TRAAK K+ channel in a Tl+ bound conductive conformation | Descriptor: | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... | Authors: | Brohawn, S.G, MacKinnon, R. | Deposit date: | 2014-09-15 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
|
|
4WFE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wfe by Molmil](/molmil-images/mine/4wfe) | Human TRAAK K+ channel in a K+ bound conductive conformation | Descriptor: | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... | Authors: | Brohawn, S.G, MacKinnon, R. | Deposit date: | 2014-09-15 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
|
|
3JRP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jrp by Molmil](/molmil-images/mine/3jrp) | SEC13 with NUP145C (AA109-179) insertion blade | Descriptor: | FUSION PROTEIN OF PROTEIN TRANSPORT PROTEIN SEC13 AND NUCLEOPORIN NUP145 | Authors: | Brohawn, S.G, Gogola, M, Schwartz, T.U. | Deposit date: | 2009-09-08 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nat.Struct.Mol.Biol., 16, 2009
|
|
3JRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jro by Molmil](/molmil-images/mine/3jro) | NUP84-NUP145C-SEC13 edge element of the NPC lattice | Descriptor: | Fusion Protein of Protein Transport Protein SEC13 and Nucleoporin NUP145, Nucleoporin NUP84 | Authors: | Brohawn, S.G, Schwartz, T.U. | Deposit date: | 2009-09-08 | Release date: | 2009-10-27 | Last modified: | 2017-08-02 | Method: | X-RAY DIFFRACTION (4.004 Å) | Cite: | Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nat.Struct.Mol.Biol., 16, 2009
|
|
6PIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pis by Molmil](/molmil-images/mine/6pis) | |
3EWE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ewe by Molmil](/molmil-images/mine/3ewe) | Crystal Structure of the Nup85/Seh1 Complex | Descriptor: | Nucleoporin NUP85, Nucleoporin SEH1 | Authors: | Brohawn, S.G, Leksa, N.C, Rajashankar, K.R, Schwartz, T.U. | Deposit date: | 2008-10-14 | Release date: | 2008-11-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural evidence for common ancestry of the nuclear pore complex and vesicle coats. Science, 322, 2008
|
|
4WFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wff by Molmil](/molmil-images/mine/4wff) | |
4I9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i9w by Molmil](/molmil-images/mine/4i9w) | |
3UM7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3um7 by Molmil](/molmil-images/mine/3um7) | |
6CNK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cnk by Molmil](/molmil-images/mine/6cnk) | Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | Descriptor: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Hibbs, R.E. | Deposit date: | 2018-03-08 | Release date: | 2018-05-02 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. Nature, 557, 2018
|
|
6CNJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cnj by Molmil](/molmil-images/mine/6cnj) | Structure of the 2alpha3beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | Descriptor: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Teng, J, Hibbs, R.E. | Deposit date: | 2018-03-08 | Release date: | 2018-05-02 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. Nature, 557, 2018
|
|
6NRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nrb by Molmil](/molmil-images/mine/6nrb) | hTRiC-hPFD Class2 | Descriptor: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | Authors: | Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | Deposit date: | 2019-01-23 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
|
|
6NRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nrc by Molmil](/molmil-images/mine/6nrc) | hTRiC-hPFD Class3 | Descriptor: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | Authors: | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | Deposit date: | 2019-01-23 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
|
|
6NR9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nr9 by Molmil](/molmil-images/mine/6nr9) | hTRiC-hPFD Class5 | Descriptor: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | Authors: | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | Deposit date: | 2019-01-23 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
|
|