4I9W

Human two pore domain K+ channel TRAAK (K2P4.1) - Fab complex structure

Summary for 4I9W

Entry DOI	10.2210/pdb4i9w/pdb
Descriptor	Potassium channel subfamily K member 4, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ... (6 entities in total)
Functional Keywords	potassium ion channel, metal transport
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Multi-pass membrane protein (Potential): Q9NYG8
Total number of polymer chains	6
Total formula weight	160472.83
Authors	Brohawn, S.G.,Mackinnon, R. (deposition date: 2012-12-05, release date: 2013-01-23, Last modification date: 2023-09-20)
Primary citation	Brohawn, S.G.,Campbell, E.B.,Mackinnon, R. Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel. Proc.Natl.Acad.Sci.USA, 110:2129-2134, 2013 Cited by PubMed: 23341632 DOI: 10.1073/pnas.1218950110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation