4I9W
Human two pore domain K+ channel TRAAK (K2P4.1) - Fab complex structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Potassium channel subfamily K member 4 | polymer | 309 | 33585.8 | 2 | UniProt (Q9NYG8) Pfam (PF07885) | Homo sapiens (human) | TWIK-related arachidonic acid-stimulated potassium channel protein, TRAAK, Two pore potassium channel KT4.1, Two pore K(+) channel KT4.1 |
| 2 | C, E (D, F) | ANTIBODY FAB FRAGMENT LIGHT CHAIN | polymer | 211 | 23038.4 | 2 | Mus musculus (mouse) | ||
| 3 | D, F (E, G) | ANTIBODY FAB FRAGMENT HEAVY CHAIN | polymer | 217 | 23474.4 | 2 | Mus musculus (mouse) | ||
| 4 | G, H, J, K, L (A, B) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
| 5 | I, M (A, G) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | N, O, P, Q, R... (A, B, D, E, F...) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: Q9NYG8)
| PDB | External Database | Details |
|---|---|---|
| Gln 104 | Asn 78 | engineered mutation |
| Gln 108 | Asn 82 | engineered mutation |
| Ser 301 | - | expression tag |
| Asn 302 | - | expression tag |
| Ser 303 | - | expression tag |
| Leu 304 | - | expression tag |
| Glu 305 | - | expression tag |
| Val 306 | - | expression tag |
| Leu 307 | - | expression tag |
| Phe 308 | - | expression tag |
| Gln 309 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 160197.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 275.6 | |
| All* | Total formula weight | 160472.8 |
