4I9W
Human two pore domain K+ channel TRAAK (K2P4.1) - Fab complex structure
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Potassium channel subfamily K member 4 | polymer | 309 | 33585.8 | 2 | UniProt (Q9NYG8) Pfam (PF07885) In PDB | Homo sapiens (human) | TWIK-related arachidonic acid-stimulated potassium channel protein, TRAAK, Two pore potassium channel KT4.1, Two pore K(+) channel KT4.1 |
2 | D, F | ANTIBODY FAB FRAGMENT LIGHT CHAIN | polymer | 211 | 23038.4 | 2 | Mus musculus (mouse) | ||
3 | E, G | ANTIBODY FAB FRAGMENT HEAVY CHAIN | polymer | 217 | 23474.4 | 2 | Mus musculus (mouse) | ||
4 | A, B | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
5 | A, G | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
6 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: Q9NYG8)
PDB | External Database | Details |
---|---|---|
Gln 104 | Asn 78 | engineered mutation |
Gln 108 | Asn 82 | engineered mutation |
Ser 301 | - | expression tag |
Asn 302 | - | expression tag |
Ser 303 | - | expression tag |
Leu 304 | - | expression tag |
Glu 305 | - | expression tag |
Val 306 | - | expression tag |
Leu 307 | - | expression tag |
Phe 308 | - | expression tag |
Gln 309 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 160197.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 275.6 | |
All* | Total formula weight | 160472.8 |