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PDB: 14 results
8DG9
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BU of 8dg9 by Molmil
Cryo-EM Structure of RSV prefusion F trimer in complex with three MxR Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAb MxR Heavy Chain, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2022-06-23
Release date:2023-02-22
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
8DG8
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BU of 8dg8 by Molmil
Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3x1 monoclonal antibody, VH region, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2022-06-23
Release date:2023-02-22
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
7U62
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BU of 7u62 by Molmil
Crystal structure of Anti-Heroin Antibody HY4-1F9 Fab Complexed with Morphine
Descriptor: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, ACETATE ION, HY4-1F9 Fab Heavy Chain, ...
Authors:Rodarte, J.V, Pancera, M.P.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
7U63
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BU of 7u63 by Molmil
Crystal Structure Anti-Oxycodone Antibody HY2-A12 Fab Complexed with Oxycodone
Descriptor: 14-hydroxy-3-methoxy-17-methyl-5beta-4,5-epoxymorphinan-6-one, HY2-A12 Fab Heavy Chain, HY2-A12 Fab Light Chain
Authors:Rodarte, J.V, Pancera, M.P, Weidle, C, Rupert, P.B, Strong, R.K.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
7U64
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BU of 7u64 by Molmil
Crystal Structure of Anti-Fentanyl Antibody HY6-F9.6 Fab Complexed with Fentanyl
Descriptor: ACETATE ION, HY6-F9.6 Fab heavy chain, HY6-F9.6 Fab light chain, ...
Authors:Rodarte, J.V, Pancera, M.P.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
9AXN
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BU of 9axn by Molmil
Crystal Structure of Anti-Fentanyl Antibody HY11-6B2_Mu Fab in Complex with Fentanyl
Descriptor: 1,2-ETHANEDIOL, HY11-6B2_Mu Fab Heavy Chain, HY11-6B2_Mu Fab Light Chain, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2024-03-06
Release date:2024-10-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published
7U61
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BU of 7u61 by Molmil
Crystal Structure of Anti-Nicotine Antibody NIC311 Fab Complexed with Nicotine
Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, NIC311 Fab Heavy Chain, NIC311 Fab Light Chain, ...
Authors:Rodarte, J.V, Pancera, M.P, Liban, T.L.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
9AXQ
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BU of 9axq by Molmil
Crystal Structure of HY11-7E1_Hu3 Fab in the Apo Conformation
Descriptor: ACETATE ION, HY11-7E1_Hu3 Fab Heavy Chain, HY11-7E1_Hu3 Fab Light Chain, ...
Authors:Rodarte, J.V, Pancera, M, Hannon, B.
Deposit date:2024-03-06
Release date:2024-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published
9AXP
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BU of 9axp by Molmil
Crystal Structure of HY11-7E1_Hu3 Fab in Complex with Carfentanil
Descriptor: ACETATE ION, HY11-7E1_Hu3 Fab Heavy Chain, HY11-7E1_Hu3 Fab Light Chain, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2024-03-06
Release date:2024-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published
9AXO
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BU of 9axo by Molmil
Crystal Structure of Antibody HY11-7E1_Ch2 Fab in Complex with Fentanyl
Descriptor: GLYCEROL, HY11-7E1_Ch2 Fab Heavy Chain, HY11-7E1_Ch2 Fab Light Chain, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2024-03-06
Release date:2024-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published
6WIT
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BU of 6wit by Molmil
Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold
Descriptor: 16055 V1V2 1FD6 Scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, NHP GN1-SD7 Fab Heavy Chain, ...
Authors:Liban, T, Aljedani, S, Rodarte, J, Pancera, M.
Deposit date:2020-04-10
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6XLZ
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BU of 6xlz by Molmil
Structure of NHP D11A.F2 Fab in complex with 16055 V2b peptide
Descriptor: (R,R)-2,3-BUTANEDIOL, Envelope glycoprotein gp160, NHP_D11A.F2_Fab_Heavy_chain, ...
Authors:Aljedani, S, Rodarte, J, Liban, T, Pancera, M.
Deposit date:2020-06-29
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
9AXS
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BU of 9axs by Molmil
Crystal Structure of HY18-5B1_Ch Fab in the Apo Conformation
Descriptor: GLYCEROL, HY18-5B1_Ch Fab Heavy Chain, HY18-5B1_Ch Fab Light Chain
Authors:McGovern, M.R, Rodarte, J.V, Pancera, M.
Deposit date:2024-03-06
Release date:2024-10-02
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published
9AXR
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BU of 9axr by Molmil
Crystal Structure of HY18-5B1_Ch Fab in Complex with Fentanyl
Descriptor: HY18-5B1_Ch Fab Heavy Chain, HY18-5B1_Ch Fab Light Chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
Authors:McGovern, M.R, Rodarte, J.V, Pancera, M.
Deposit date:2024-03-06
Release date:2024-10-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published

226707

数据于2024-10-30公开中

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