9AXR

Crystal Structure of HY18-5B1_Ch Fab in Complex with Fentanyl

Summary for 9AXR

• Entry DOI: 10.2210/pdb9axr/pdb
• Descriptor: HY18-5B1_Ch Fab Heavy Chain, HY18-5B1_Ch Fab Light Chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide (3 entities in total)
• Functional Keywords: opioids, mab, fentanyl, cross-reactive, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 145898.81

Authors

McGovern, M.R.,Rodarte, J.V.,Pancera, M. (deposition date: 2024-03-06, release date: 2024-10-02)

• Primary citation: Rodarte, J.V.,Pravetoni, M.; Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.3 Å)