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PDB: 70 件
5MP7
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Crystal structure of phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
分子名称: ACETATE ION, Ribose-phosphate pyrophosphokinase
著者Donini, S, Garavaglia, S, Ferraris, D.M, Miggiano, R, Mori, S, Shibayama, K, Rizzi, M.
登録日2016-12-16
公開日2017-04-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis.
PLoS ONE, 12, 2017
6TGW
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Crystal structure of human Aldehyde dehydrogenase 1A3 in complex with a selective inhibitor
分子名称: Aldehyde dehydrogenase family 1 member A3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, methyl 5-(1,3-benzodioxol-5-yl)-2-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxylate
著者Garavaglia, S, Rizzi, M.
登録日2019-11-18
公開日2021-06-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.
Commun Biol, 4, 2021
5HKI
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Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with Fe(III) dicitrate
分子名称: Iron(III) dicitrate, Orotate phosphoribosyltransferase
著者Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M.
登録日2016-01-14
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.
Sci Rep, 7, 2017
6T3E
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Structure of Thermococcus litoralis Delta(1)-pyrroline-2-carboxylate reductase in complex with NADH and L-proline
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DELTA1-pyrroline-2-carboxylate reductase, PROLINE
著者Ferraris, D.M, Miggiano, R, Ferrario, E, Rizzi, M.
登録日2019-10-10
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Thermococcus litoralis Delta1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline.
Acta Crystallogr D Struct Biol, 76, 2020
5HKF
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Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Orotate phosphoribosyltransferase
著者Donini, S, Ferraris, D.M, Bolognesi, G, Rizzi, M.
登録日2016-01-14
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.
Sci Rep, 7, 2017
5HKL
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Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with inorganic phosphate
分子名称: Orotate phosphoribosyltransferase, PHOSPHATE ION
著者Donini, S, Bolognesi, G, Rizzi, M.
登録日2016-01-14
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.
Sci Rep, 7, 2017
7QPO
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Crystal structure of human trans-3-Hydroxy-L-proline dehydratase
分子名称: Trans-3-hydroxy-L-proline dehydratase
著者Ferrario, E, Miggiano, R, Rizzi, M, Ferraris, D.M.
登録日2022-01-05
公開日2022-08-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The integration of AlphaFold-predicted and crystal structures of human trans -3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism.
Comput Struct Biotechnol J, 20, 2022
2WM1
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BU of 2wm1 by Molmil
The crystal structure of human alpha-amino-beta-carboxymuconate- epsilon-semialdehyde decarboxylase in complex with 1,3- dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE, GLYCEROL, ...
著者Garavaglia, S, Perozzi, S, Galeazzi, L, Raffaelli, N, Rizzi, M.
登録日2009-06-29
公開日2009-11-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The Crystal Structure of Human Alpha-Amino-Beta-Carboxymuconate-Epsilon-Semialdehyde Decarboxylase in Complex with 1,3-Dihydroxyacetonephosphate Suggests a Regulatory Link between Nad Synthesis and Glycolysis
FEBS J., 276, 2009
3ZUK
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN COMPLEX WITH INHIBITOR
分子名称: 2,2',2''-NITRILOTRIETHANOL, ACETATE ION, CALCIUM ION, ...
著者Ferraris, D.M, Sbardella, D, Petrera, A, Marini, S, Amstutz, B, Coletta, M, Sander, P, Rizzi, M.
登録日2011-07-19
公開日2011-08-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Mycobacterium Tuberculosis Zinc-Dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity.
J.Biol.Chem., 286, 2011
3ZQJ
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Mycobacterium tuberculosis UvrA
分子名称: UVRABC SYSTEM PROTEIN A, ZINC ION
著者Rossi, F, Khanduja, J.S, Bortoluzzi, A, Houghton, J, Sander, P, Guthlein, C, Davis, E.O, Springer, B, Bottger, E.C, Relini, A, Penco, A, Muniyappa, K, Rizzi, M.
登録日2011-06-09
公開日2011-06-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Biological and Structural Characterization of Mycobacterium Tuberculosis Uvra Provides Novel Insights Into its Mechanism of Action
Nucleic Acids Res., 39, 2011
4LVQ
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BU of 4lvq by Molmil
Crystal structure of the M. tuberculosis phosphate binding protein PstS3
分子名称: PHOSPHATE ION, Phosphate-binding protein PstS 3
著者Ferraris, D.M, Rizzi, M.
登録日2013-07-26
公開日2014-03-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3.
Proteins, 82, 2014
2HUI
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BU of 2hui by Molmil
Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase in complex with glyoxylic acid
分子名称: Alanine glyoxylate aminotransferase, GLYOXYLIC ACID
著者Han, Q, Robinson, H, Gao, Y.G, Vogelaar, N, Wilson, S.R, Rizzi, M, Li, J.
登録日2006-07-26
公開日2006-09-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem., 281, 2006
2HUU
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Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase in complex with alanine
分子名称: 1-BUTANOL, ALANINE, Alanine glyoxylate aminotransferase
著者Han, Q, Robinson, H, Gao, Y.G, Vogelaar, N, Wilson, S.R, Rizzi, M, Li, J.
登録日2006-07-27
公開日2006-09-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem., 281, 2006
2HUF
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BU of 2huf by Molmil
Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase
分子名称: 1-BUTANOL, Alanine glyoxylate aminotransferase
著者Han, Q, Robinson, H, Gao, Y.G, Vogelaar, N, Wilson, S.R, Rizzi, M, Li, J.
登録日2006-07-26
公開日2006-09-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem., 281, 2006
4ZYE
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BU of 4zye by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase
分子名称: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase, NITRATE ION
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYD
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BU of 4zyd by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
分子名称: DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
2CH2
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BU of 2ch2 by Molmil
Structure of the Anopheles gambiae 3-hydroxykynurenine transaminase in complex with inhibitor
分子名称: 3-HYDROXYKYNURENINE TRANSAMINASE, 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Rossi, F, Garavaglia, S, Giovenzana, G.B, Arca, B, Li, J, Rizzi, M.
登録日2006-03-10
公開日2006-03-28
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the Anopheles Gambiae 3-Hydroxykynurenine Transaminase
Proc.Natl.Acad.Sci.USA, 103, 2006
2CH1
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Structure of Anopheles gambiae 3-hydroxykynurenine transaminase
分子名称: 3-HYDROXYKYNURENINE TRANSAMINASE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE
著者Rossi, F, Garavaglia, S, Giovenzana, G.B, Arca, B, Li, J, Rizzi, M.
登録日2006-03-10
公開日2006-03-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Anopheles Gambiae 3-Hydroxykynurenine Transaminase
Proc.Natl.Acad.Sci.USA, 103, 2006
4ZYG
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Crystal structure of methylated Sulfolobus solfataricus O6-methylguanine methyltransferase
分子名称: Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYH
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Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119L variant
分子名称: Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
3ZTV
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Structure of Haemophilus influenzae NAD nucleotidase (NadN)
分子名称: ADENOSINE, GLYCEROL, NAD NUCLEOTIDASE, ...
著者Garavaglia, S, Bruzzone, S, Cassani, C, Canella, L, Allegrone, G, Sturla, L, Mannino, E, Millo, E, De Flora, A, Rizzi, M.
登録日2011-07-12
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
Biochem.J., 441, 2012
1UMA
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BU of 1uma by Molmil
ALPHA-THROMBIN (HIRUGEN) COMPLEXED WITH NA-(N,N-DIMETHYLCARBAMOYL)-ALPHA-AZALYSINE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN, HIRUDIN I, ...
著者Nardini, M, Pesce, A, Rizzi, M, Casale, E, Ferraccioli, R, Balliano, G, Milla, P, Ascenzi, P, Bolognesi, M.
登録日1996-03-26
公開日1996-11-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
J.Mol.Biol., 258, 1996
2XSR
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BU of 2xsr by Molmil
Crystal structure of wild type Acinetobacter radioresistens catechol 1,2 dioxygenase
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, CATECHOL 1,2 DIOXYGENASE, FE (III) ION
著者Micalella, C, Martignon, S, Bruno, S, Rizzi, M.
登録日2010-09-30
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Crystallography, Mass Spectrometry and Single Crystal Microspectrophotometry: A Multidisciplinary Characterization of Catechol 1,2 Dioxygenase.
Biochim.Biophys.Acta, 1814, 2011
4YUB
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Crystal structure of human Nicotinic Acid Phosphoribosyltransferase
分子名称: Nicotinate phosphoribosyltransferase
著者Garavaglia, S, Rizzi, M, Marletta, A.S.
登録日2015-03-18
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human nicotinic acid phosphoribosyltransferase.
Febs Open Bio, 5, 2015
3ZU0
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BU of 3zu0 by Molmil
Structure of Haemophilus influenzae NAD nucleotidase (NadN)
分子名称: NAD NUCLEOTIDASE, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Garavaglia, S, Bruzzone, S, Cassani, C, Canella, L, Allegrone, G, Sturla, L, Mannino, E, Millo, E, De Flora, A, Rizzi, M.
登録日2011-07-13
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献The High-Resolution Crystal Structure of Periplasmic Haemophilus Influenzae Nad Nucleotidase Reveals a Novel Enzymatic Function of Human Cd73 Related to Nad Metabolism.
Biochem.J., 441, 2012

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