5HKI
Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with Fe(III) dicitrate
Summary for 5HKI
Entry DOI | 10.2210/pdb5hki/pdb |
Descriptor | Orotate phosphoribosyltransferase, Iron(III) dicitrate (3 entities in total) |
Functional Keywords | oprt, de novo pyrimidine nucleotide synthesis, ferric dicitrate complex, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 4 |
Total formula weight | 81679.41 |
Authors | Donini, S.,Ferraris, D.M.,Bolognesi, G.,Rizzi, M. (deposition date: 2016-01-14, release date: 2017-01-25, Last modification date: 2024-01-10) |
Primary citation | Donini, S.,Ferraris, D.M.,Miggiano, R.,Massarotti, A.,Rizzi, M. Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis. Sci Rep, 7:1180-1180, 2017 Cited by PubMed: 28446777DOI: 10.1038/s41598-017-01057-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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