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PDB: 15 results

5UN7
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Structure of the human POT1-TPP1 telomeric complex
Descriptor: Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ...
Authors:Rice, C, Doukov, T, Skordalakes, E.
Deposit date:2017-01-30
Release date:2017-04-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional analysis of the human POT1-TPP1 telomeric complex.
Nat Commun, 8, 2017
5W2L
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Structure of a central domain of human Ctc1
Descriptor: CST complex subunit CTC1, MERCURY (II) ION
Authors:Rice, C, Skordalakes, E.
Deposit date:2017-06-06
Release date:2017-11-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.
Nucleic Acids Res., 46, 2018
4JQF
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Structure of the C-terminal domain of human telomeric Stn1
Descriptor: CST complex subunit STN1
Authors:Bryan, C.F, Rice, C.T, Harkisheimer, M, Schultz, D, Skordalakes, E.
Deposit date:2013-03-20
Release date:2013-06-05
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
3KQH
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*AP*AP*AP*AP*AP*A)-3', Serine protease/NTPase/helicase NS3
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQN
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQU
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*T*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inaugural Article: Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
4J1V
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Functional and structural studies of MOBKL1B, a Salvador/Warts/Hippo tumor suppressor pathway, in HCV replication
Descriptor: MOB kinase activator 1A, NS5A domain II peptide, ZINC ION
Authors:Chung, H.-Y, Gu, M, Rice, C.M.
Deposit date:2013-02-02
Release date:2014-08-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction.
J.Virol., 88, 2014
3KQK
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*TP*TP*TP*TP*TP*T)-3', Serine protease/NTPase/helicase NS3
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
4JOI
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Crystal structure of the human telomeric Stn1-Ten1 complex
Descriptor: CST complex subunit STN1, CST complex subunit TEN1
Authors:Bryan, C, Rice, C, Harkisheimer, M, Schultz, D, Skordalakes, E.
Deposit date:2013-03-18
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
3KQL
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
1A1R
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BU of 1a1r by Molmil
HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX
Descriptor: NS3 PROTEIN, NS4A PROTEIN, ZINC ION
Authors:Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A.
Deposit date:1997-12-15
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.
Cell(Cambridge,Mass.), 87, 1996
5E4F
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The spring alpha-helix coordinates multiple modes of HCV NS3 helicase action
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine protease NS3, ...
Authors:Gu, M, Rice, C.M.
Deposit date:2015-10-05
Release date:2016-05-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Spring alpha-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action.
J.Biol.Chem., 291, 2016
5CQG
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BU of 5cqg by Molmil
Structure of Tribolium telomerase in complex with the highly specific inhibitor BIBR1532
Descriptor: 2-{[(2E)-3-(naphthalen-2-yl)but-2-enoyl]amino}benzoic acid, Telomerase reverse transcriptase
Authors:Bryan, C, Rice, C, Hoffman, H, Harkisheimer, M, Sweeney, M, Skordalakes, E.
Deposit date:2015-07-21
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532.
Structure, 23, 2015
2HD0
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Structure of the catalytic domain of hepatitis C virus NS2
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, Protease NS2-3 (p23), octyl beta-D-glucopyranoside
Authors:Lorenz, I.C, Rice, C.M, Marcotrigiano, J.
Deposit date:2006-06-19
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.
Nature, 442, 2006
1ZH1
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Structure of the zinc-binding domain of HCV NS5A
Descriptor: ZINC ION, non-structural polyprotein
Authors:Tellinghuisen, T.L, Marcotrigiano, J, Rice, C.M.
Deposit date:2005-04-22
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.
Nature, 435, 2005

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