5E4F

The spring alpha-helix coordinates multiple modes of HCV NS3 helicase action

Summary for 5E4F

• Entry DOI: 10.2210/pdb5e4f/pdb
• Descriptor: Serine protease NS3, TETRAFLUOROALUMINATE ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: hcv ns3 helicase, transition state, hydrolase
• Biological source: Hepatitis C virus genotype 1b (isolate Con1) (HCV)
• Total number of polymer chains: 2
• Total formula weight: 94593.08

Authors

Gu, M.,Rice, C.M. (deposition date: 2015-10-05, release date: 2016-05-18, Last modification date: 2024-03-06)

• Primary citation: Gu, M.,Rice, C.M.; The Spring alpha-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action.; J.Biol.Chem., 291:14499-14509, 2016; PubMed: 27226535; DOI: 10.1074/jbc.M115.704379

Experimental method

X-RAY DIFFRACTION (2.1 Å)