5NUH
 
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2JDQ
 | | C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 | | Descriptor: | IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2 | | Authors: | Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S. | | Deposit date: | 2007-01-11 | | Release date: | 2007-02-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit
Nat.Struct.Mol.Biol., 14, 2007
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2P2K
 | | Crystal structure of a lectin from Canavalia gladiata seeds (CGL) in complex with man1-4man-OMe | | Descriptor: | CALCIUM ION, Canavalia gladiata lectin, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Bezerra, G.A, Oliveira, T.M, Souza, E.P, Rocha, B.A.M, Benevides, G.B, Delatorre, P, Cavada, B.S, de Azevedo Jr, W.F. | | Deposit date: | 2007-03-07 | | Release date: | 2007-10-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: New insights into the understanding of the structure-biological activity relationship in legume lectins.
J.Struct.Biol., 160, 2007
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2P37
 | | Crystal structure of a lectin from Canavalia maritima seeds (CML) in complex with man1-3man-OMe | | Descriptor: | CALCIUM ION, Concanavalin A, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Bezerra, G.A, Oliveira, T.M, Souza, E.P, Rocha, B.A.M, Benevides, R.G, Delatorre, P, Cavada, B.S, de Azevedo Jr, W. | | Deposit date: | 2007-03-08 | | Release date: | 2007-11-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: New insights into the understanding of the structure-biological activity relationship in legume lectins.
J.Struct.Biol., 160, 2007
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2OW4
 | | Crystal structure of a lectin from Canavalia maritima seeds (ConM) in complex with man1-2man-OMe | | Descriptor: | CALCIUM ION, Canavalia maritima lectin, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Bezerra, G.A, de Oliveira, T.M, de Souza, E.M, da Rocha, B.A.M, Benevides, R.G, Delatorre, P, Cavada, B.S, de Azevedo Jr, W.F. | | Deposit date: | 2007-02-15 | | Release date: | 2007-10-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: New insights into the understanding of the structure-biological activity relationship in legume lectins.
J.Struct.Biol., 160, 2007
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2OVU
 | | Crystal structure of a lectin from Canavalia gladiata (CGL) in complex with man1-2man-OMe | | Descriptor: | CALCIUM ION, Canavalia gladiata lectin, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Bezerra, G.A, de Oliveira, T.M, de Souza, E.P, da Rocha, B.A.M, Benevides, R.G, Delatorre, P, Cavada, B.S, de Azevedo Jr, W.F. | | Deposit date: | 2007-02-15 | | Release date: | 2007-10-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: New insights into the understanding of the structure-biological activity relationship in legume lectins.
J.Struct.Biol., 160, 2007
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2VY6
 | | Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit | | Descriptor: | POLYMERASE BASIC PROTEIN 2 | | Authors: | Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. | | Deposit date: | 2008-07-18 | | Release date: | 2008-09-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
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2VY8
 | | The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627 | | Descriptor: | POLYMERASE BASIC PROTEIN 2 | | Authors: | Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. | | Deposit date: | 2008-07-19 | | Release date: | 2008-09-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
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2VY7
 | | The 627-domain from influenza A virus polymerase PB2 subunit | | Descriptor: | POLYMERASE BASIC PROTEIN 2 | | Authors: | Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. | | Deposit date: | 2008-07-18 | | Release date: | 2008-09-09 | | Last modified: | 2012-06-06 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit
Plos Pathog., 4, 2008
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2P34
 | | Crystal structure of a lectin from Canavalia maritima seeds (CML) in complex with man1-4man-OMe | | Descriptor: | CALCIUM ION, Lectin, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Bezerra, G.A, Oliveira, T.M, Souza, E.P, Rocha, B.A.M, Benevides, R.G, Delatorre, P, Cavada, B.S, de Azevedo Jr, W. | | Deposit date: | 2007-03-08 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: new insights into the understanding of the structure-biological activity relationship in legume lectins.
J.Struct.Biol., 160, 2007
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2EF6
 | | Canavalia gladiata lectin complexed with Man1-3Man-OMe | | Descriptor: | CALCIUM ION, Concanavalin A, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Bezerra, G.A, Oliveira, T.M, de Souza, E.P, da Rocha, B.A.M, Benevides, R.G, Delatorre, P, Cavada, B.S, de Azevedo Jr, W.F. | | Deposit date: | 2007-02-21 | | Release date: | 2007-10-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: New insights into the understanding of the structure-biological activity relationship in legume lectins
J.Struct.Biol., 160, 2007
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2EIG
 | | Lotus tetragonolobus seed lectin (Isoform) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ... | | Authors: | Moreno, F.B.M.B, Vicoti, M.M, Abrego, J.R.B, de Oliveira, T.M, Bezerra, G.A, Cavada, B.S, Filgueira de Azevedo Jr, W. | | Deposit date: | 2007-03-13 | | Release date: | 2008-03-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification of a new quaternary association for legume lectins
J.Struct.Biol., 161, 2008
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2C1W
 | | The structure of XendoU: a splicing independent snoRNA processing endoribonuclease | | Descriptor: | ENDOU PROTEIN, PHOSPHATE ION | | Authors: | Renzi, F, Caffarelli, E, Laneve, P, Bozzoni, I, Brunori, M, Vallone, B. | | Deposit date: | 2005-09-21 | | Release date: | 2006-07-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Structure of the Endoribonuclease Xendou: From Small Nucleolar RNA Processing to Severe Acute Respiratory Syndrome Coronavirus Replication.
Proc.Natl.Acad.Sci.USA, 103, 2006
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2C9J
 | | Structure of the fluorescent protein cmFP512 at 1.35A from Cerianthus membranaceus | | Descriptor: | GREEN FLUORESCENT PROTEIN FP512 | | Authors: | Renzi, F, Nienhaus, K, Wiedenmann, J, Vallone, B, Nienhaus, G.U. | | Deposit date: | 2005-12-12 | | Release date: | 2006-10-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Exploring Chromophore-Protein Interactions in Fluorescent Protein Cmfp512 from Cerianthus Membranaceus: X-Ray Structure Analysis and Optical Spectroscopy.
Biochemistry, 45, 2006
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2C9I
 | | Structure of the fluorescent protein asFP499 from Anemonia sulcata | | Descriptor: | GREEN FLUORESCENT PROTEIN ASFP499 | | Authors: | Renzi, F, Nienhaus, K, Wiedenmann, J, Vallone, B, Nienhaus, G.U. | | Deposit date: | 2005-12-12 | | Release date: | 2007-01-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Chromophore-Protein Interactions in the Anthozoan Green Fluorescent Protein Asfp499
Biophys.J., 91, 2006
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1U9N
 | | Crystal structure of the transcriptional regulator EthR in a ligand bound conformation opens therapeutic perspectives against tuberculosis and leprosy | | Descriptor: | HEXADECYL OCTANOATE, Transcriptional repressor EthR | | Authors: | Frenois, F, Engohang-Ndong, J, Locht, C, Baulard, A.R, Villeret, V. | | Deposit date: | 2004-08-10 | | Release date: | 2004-11-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis
Mol.Cell, 16, 2004
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1U9O
 | | Crystal structure of the transcriptional regulator EthR in a ligand bound conformation | | Descriptor: | HEXADECYL OCTANOATE, Transcriptional repressor EthR | | Authors: | Frenois, F, Engohang-Ndong, J, Locht, C, Baulard, A.R, Villeret, V. | | Deposit date: | 2004-08-10 | | Release date: | 2004-11-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis
Mol.Cell, 16, 2004
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3VNJ
 | | Crystal structures of D-Psicose 3-epimerase with D-psicose from Clostridium cellulolyticum H10 | | Descriptor: | D-psicose, MANGANESE (II) ION, Xylose isomerase domain protein TIM barrel | | Authors: | Chan, H.C, Zhu, Y, Hu, Y, Ko, T.P, Huang, C.H, Ren, F, Chen, C.C, Guo, R.T, Sun, Y. | | Deposit date: | 2012-01-16 | | Release date: | 2012-08-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars.
Protein Cell, 3, 2012
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6M84
 | | Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | | Descriptor: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | | Authors: | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | | Deposit date: | 2018-08-21 | | Release date: | 2019-09-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
J.Gen.Physiol., 152, 2020
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8WJY
 | | PKMYT1_Cocrystal_Cpd 4 | | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | | Authors: | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | | Deposit date: | 2023-09-26 | | Release date: | 2023-11-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 67, 2024
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5KUK
 | | Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant | | Descriptor: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION | | Authors: | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | | Deposit date: | 2016-07-13 | | Release date: | 2016-08-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
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5KUM
 | | Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2 | | Descriptor: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION, ... | | Authors: | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | | Deposit date: | 2016-07-13 | | Release date: | 2016-08-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
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8J1K
 | | co-crystal structure of non-carboxylic acid inhibitor with PHD2 | | Descriptor: | Egl nine homolog 1, MANGANESE (II) ION, N-[(6-cyanopyridin-3-yl)methyl]-5-oxidanyl-2-[(3R)-3-oxidanylpyrrolidin-1-yl]-1,7-naphthyridine-6-carboxamide | | Authors: | Xu, J, Fu, Y, Ding, X, Meng, Q, Wang, L, Zhang, M, Ding, X, Ren, F, Zhavoronkov, A. | | Deposit date: | 2023-04-13 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (2.451 Å) | | Cite: | co-crystal structure of non-carboxylic acid inhibitor with PHD2
To Be Published
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5GT1
 | | crystal structure of cbpa from L. salivarius REN | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Choline binding protein A, ... | | Authors: | Jiang, L, Ren, F. | | Deposit date: | 2016-08-18 | | Release date: | 2017-07-19 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins
Sci Rep, 7, 2017
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1VYW
 | | Structure of CDK2/Cyclin A with PNU-292137 | | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, N-(3-CYCLOPROPYL-1H-PYRAZOL-5-YL)-2-(2-NAPHTHYL)ACETAMIDE, ... | | Authors: | Pevarello, P, Brasca, M.G, Amici, R, Orsini, P, Traquandi, G, Corti, L, Piutti, C, Sansonna, P, Villa, M, Pierce, B.S, Pulici, M, Giordano, P, Martina, K, Fritzen, E.L, Nugent, R.A, Casale, E, Cameron, A, Ciomei, M, Roletto, F, Isacchi, A, Fogliatto, G, Pesenti, E, Pastori, W, Marsiglio, A, Leach, K.L, Clare, P.M, Fiorentini, F, Varasi, M, Vulpetti, A, Warpehoski, M.A. | | Deposit date: | 2004-05-07 | | Release date: | 2004-06-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | 3-Aminopyrazole Inhibitors of Cdk2/Cyclin a as Antitumor Agents. Part 1. Lead Finding
J.Med.Chem., 47, 2004
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