5KUM

Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2

Summary for 5KUM

• Entry DOI: 10.2210/pdb5kum/pdb
• Related: 5KUK
• Descriptor: ATP-sensitive inward rectifier potassium channel 12, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, POTASSIUM ION, ... (5 entities in total)
• Functional Keywords: metal transport, kir 2.2 k62w mutant structure
• Biological source: Gallus gallus (Chicken)
• Cellular location: Membrane; Multi-pass membrane protein: F1NHE9
• Total number of polymer chains: 1
• Total formula weight: 40960.67

Authors

Lee, S.-J.,Ren, F.,Heyman, S.,Yuan, P.,Nichols, C.G. (deposition date: 2016-07-13, release date: 2016-08-10, Last modification date: 2023-10-04)

• Primary citation: Lee, S.J.,Ren, F.,Zangerl-Plessl, E.M.,Heyman, S.,Stary-Weinzinger, A.,Yuan, P.,Nichols, C.G.; Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.; J.Gen.Physiol., 148:227-237, 2016; PubMed: 27527100; DOI: 10.1085/jgp.201611616

Experimental method

X-RAY DIFFRACTION (2.8 Å)