3JWE
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![BU of 3jwe by Molmil](/molmil-images/mine/3jwe) | Crystal structure of human mono-glyceride lipase in complex with SAR629 | Descriptor: | 1-[bis(4-fluorophenyl)methyl]-4-(1H-1,2,4-triazol-1-ylcarbonyl)piperazine, MGLL protein | Authors: | Bertrand, T, Auge, F, Houtmann, J, Rak, A, Vallee, F, Mikol, V, Berne, P.F, Michot, N, Cheuret, D, Hoornaert, C, Mathieu, M. | Deposit date: | 2009-09-18 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for human monoglyceride lipase inhibition. J.Mol.Biol., 396, 2010
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1QTK
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![BU of 1qtk by Molmil](/molmil-images/mine/1qtk) | CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF KRYPTON (55 BAR) | Descriptor: | CHLORIDE ION, KRYPTON, LYSOZYME, ... | Authors: | Prange, T, Schiltz, M, Pernot, L, Colloc'h, N, Longhi, S, Bourguet, W, Fourme, R. | Deposit date: | 1999-06-28 | Release date: | 1999-07-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Exploring hydrophobic sites in proteins with xenon or krypton. Proteins, 30, 1998
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3BS5
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![BU of 3bs5 by Molmil](/molmil-images/mine/3bs5) | Crystal Structure of hCNK2-SAM/dHYP-SAM Complex | Descriptor: | Connector enhancer of kinase suppressor of ras 2, Protein aveugle | Authors: | Rajakulendran, T, Ceccarelli, D.F, Kurinov, I, Sicheri, F. | Deposit date: | 2007-12-22 | Release date: | 2008-02-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proc.Natl.Acad.Sci.USA, 105, 2008
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6FG2
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![BU of 6fg2 by Molmil](/molmil-images/mine/6fg2) | CRYSTAL STRUCTURE OF FAB OF NATALIZUMAB IN COMPLEX WITH FAB OF NAA84. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEAVY CHAIN FAB NAA84, HEAVY CHAIN FAB NATALIZUMAB, ... | Authors: | Bertrand, T, Pouzieux, S. | Deposit date: | 2018-01-09 | Release date: | 2019-07-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.788 Å) | Cite: | A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients. Nat. Med., 25, 2019
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6EST
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8GQR
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![BU of 8gqr by Molmil](/molmil-images/mine/8gqr) | Crystal structure of VioD with FAD | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | Authors: | Ran, T, Wang, W, Xu, M. | Deposit date: | 2022-08-30 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway. Proteins, 91, 2023
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4KNF
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![BU of 4knf by Molmil](/molmil-images/mine/4knf) | Crystal structure of a blue-light absorbing proteorhodopsin double-mutant D97N/Q105L from HOT75 | Descriptor: | Blue-light absorbing proteorhodopsin, RETINAL | Authors: | Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H. | Deposit date: | 2013-05-09 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes. Acta Crystallogr.,Sect.D, 69, 2013
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4KLY
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![BU of 4kly by Molmil](/molmil-images/mine/4kly) | Crystal structure of a blue-light absorbing proteorhodopsin mutant D97N from HOT75 | Descriptor: | Blue-light absorbing proteorhodopsin, RETINAL | Authors: | Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H. | Deposit date: | 2013-05-07 | Release date: | 2013-06-05 | Last modified: | 2013-10-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes. Acta Crystallogr.,Sect.D, 69, 2013
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1C1M
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![BU of 1c1m by Molmil](/molmil-images/mine/1c1m) | PORCINE ELASTASE UNDER XENON PRESSURE (8 BAR) | Descriptor: | CALCIUM ION, PROTEIN (PORCINE ELASTASE), SULFATE ION, ... | Authors: | Prange, T, Schiltz, M, Pernot, L, Colloc'h, N, Longhi, S, Bourguet, W, Fourme, R. | Deposit date: | 1999-07-22 | Release date: | 1999-07-28 | Last modified: | 2018-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Exploring hydrophobic sites in proteins with xenon or krypton. Proteins, 30, 1998
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7PUF
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![BU of 7puf by Molmil](/molmil-images/mine/7puf) | urate oxidase azaxanthine complex under 600 bar (60 MPa) of argon | Descriptor: | 8-AZAXANTHINE, ARGON, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2021-09-29 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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5YLT
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![BU of 5ylt by Molmil](/molmil-images/mine/5ylt) | Crystal structure of SET7/9 in complex with a cyproheptadine derivative | Descriptor: | 2-(1-methylpiperidin-4-ylidene)tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-6-ol, GLYCEROL, Histone-lysine N-methyltransferase SETD7, ... | Authors: | Hirano, T, Fujiwara, T, Niwa, H, Hirano, M, Ohira, K, Okazaki, Y, Sato, S, Umehara, T, Maemoto, Y, Ito, A, Yoshida, M, Kagechika, H. | Deposit date: | 2017-10-19 | Release date: | 2018-06-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine. ChemMedChem, 13, 2018
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7PWN
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![BU of 7pwn by Molmil](/molmil-images/mine/7pwn) | URATE OXYDASE AZA-XANTHINE COMPLEX AT 1000 BARS (100 MPa) OF ARGON | Descriptor: | 8-AZAXANTHINE, ARGON, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2021-10-07 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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7Q09
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![BU of 7q09 by Molmil](/molmil-images/mine/7q09) | URATE OXIDASE AZA-XANTHINE COMPLEX UNDER 1500 BAR OF ARGON | Descriptor: | 8-AZAXANTHINE, ACETYL GROUP, ARGON, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2021-10-14 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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3KCH
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![BU of 3kch by Molmil](/molmil-images/mine/3kch) | Baranase crosslinked by glutaraldehyde | Descriptor: | PENTANEDIAL, Ribonuclease | Authors: | Prange, T, Salem, M, Mauguen, Y. | Deposit date: | 2009-10-21 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Revisiting glutaraldehyde cross-linking: the case of the Arg-Lys intermolecular doublet Acta Crystallogr.,Sect.F, 66, 2010
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3L8W
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![BU of 3l8w by Molmil](/molmil-images/mine/3l8w) | Urate oxidase from aspergillus flavus complexed with xanthin | Descriptor: | SODIUM ION, Uricase, XANTHINE, ... | Authors: | Prange, T, Gabison, L, Colloc'h, N, Chiadmi, M. | Deposit date: | 2010-01-04 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand. Acta Crystallogr.,Sect.D, 66, 2010
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6IA1
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![BU of 6ia1 by Molmil](/molmil-images/mine/6ia1) | urate oxidase under 120 bar of argon | Descriptor: | 8-AZAXANTHINE, ACETATE ION, ARGON, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-11-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6IA9
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![BU of 6ia9 by Molmil](/molmil-images/mine/6ia9) | urate oxidase under 2000 bar (220 MPa) of argon | Descriptor: | 8-AZAXANTHINE, ACETYL GROUP, ARGON, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-11-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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7A47
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![BU of 7a47 by Molmil](/molmil-images/mine/7a47) | KRASG12C GDP form in complex with Cpd4 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ~{N}-[3-bromanyl-2-(2-methylimidazol-1-yl)pyridin-4-yl]-3-[[3-bromanyl-2-(2-methylimidazol-1-yl)pyridin-4-yl]-propanoyl-amino]propanamide | Authors: | Bertrand, T, Steier, V. | Deposit date: | 2020-08-19 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | KRAS G12C fragment screening renders new binding pockets. Small Gtpases, 13, 2022
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3L9G
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![BU of 3l9g by Molmil](/molmil-images/mine/3l9g) | Urate oxidase complexed with uric acid and chloride | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Gabison, L. | Deposit date: | 2010-01-05 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand. Acta Crystallogr.,Sect.D, 66, 2010
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6IC1
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![BU of 6ic1 by Molmil](/molmil-images/mine/6ic1) | urate oxidase under 90 bar of krypton | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-12-01 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6I9X
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![BU of 6i9x by Molmil](/molmil-images/mine/6i9x) | urate oxidase under 35 bar of argon | Descriptor: | 8-AZAXANTHINE, ARGON, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N. | Deposit date: | 2018-11-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6I9Z
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![BU of 6i9z by Molmil](/molmil-images/mine/6i9z) | urate oxidase under 65 bar of argon | Descriptor: | 8-AZAXANTHINE, ARGON, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-11-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6Q8S
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![BU of 6q8s by Molmil](/molmil-images/mine/6q8s) | |
3LD4
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![BU of 3ld4 by Molmil](/molmil-images/mine/3ld4) | Urate oxidase complexed with 8-nitro xanthine | Descriptor: | 1,2-ETHANEDIOL, 8-nitro-3,7-dihydro-1H-purine-2,6-dione, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Gabison, L. | Deposit date: | 2010-01-12 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand. Acta Crystallogr.,Sect.D, 66, 2010
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6Q8R
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![BU of 6q8r by Molmil](/molmil-images/mine/6q8r) | |