3LW6
| Crystal Structure of Drosophila beta1,4-galactosyltransferase-7 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-4-galactosyltransferase 7, MANGANESE (II) ION, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2010-02-23 | Release date: | 2010-03-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7. J.Biol.Chem., 285, 2010
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3EE5
| Crystal structure of human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in complex with GLCNAC-Beta1,3-Gal-Beta-Naphthalenemethanol | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2008-09-04 | Release date: | 2009-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Deoxygenated Disaccharide Analogs as Specific Inhibitors of {beta}1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis J.Biol.Chem., 284, 2009
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213D
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2FYA
| Crystal structure of the catalytic domain of the human beta1, 4-galactosyltransferase mutant M339H complex with manganese | Descriptor: | Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, TRIETHYLENE GLYCOL | Authors: | Ramakrishnan, B, Ramasamy, V, Qasba, P.K. | Deposit date: | 2006-02-07 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357, 2006
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2FY7
| Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in apo form | Descriptor: | Beta-1,4-galactosyltransferase 1, TRIETHYLENE GLYCOL | Authors: | Ramakrishnan, B, Ramasamy, V, Qasba, P.K. | Deposit date: | 2006-02-07 | Release date: | 2006-03-14 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357, 2006
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2FYB
| Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in complex with Mn and UDP-galactose in open conformation | Descriptor: | Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE | Authors: | Ramakrishnan, B, Ramasamy, V, Qasba, P.K. | Deposit date: | 2006-02-07 | Release date: | 2006-03-14 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357, 2006
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138D
| A-DNA DECAMER D(GCGGGCCCGC)-HEXAGONAL CRYSTAL FORM | Descriptor: | DNA (5'-D(*GP*CP*GP*GP*GP*CP*CP*CP*GP*C)-3') | Authors: | Ramakrishnan, B, Sundaralingam, M. | Deposit date: | 1993-09-15 | Release date: | 1994-01-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evidence for crystal environment dominating base sequence effects on DNA conformation: crystal structures of the orthorhombic and hexagonal polymorphs of the A-DNA decamer d(GCGGGCCCGC) and comparison with their isomorphous crystal structures. Biochemistry, 32, 1993
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2FYC
| Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase-I in complex with alpha-lactalbumin, Ca and UDP-galactose | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-lactalbumin, CALCIUM ION, ... | Authors: | Ramakrishnan, B, Ramasamy, V, Qasba, P.K. | Deposit date: | 2006-02-07 | Release date: | 2006-03-14 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357, 2006
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2FYD
| catalytic domain of bovine beta 1, 4-galactosyltransferase in complex with alpha-lactalbumin, glucose, Mn, and UDP-N-acetylgalactosamine | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-galactopyranose, Alpha-lactalbumin, ... | Authors: | Ramakrishnan, B, Ramasamy, V, Qasba, P.K. | Deposit date: | 2006-02-07 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357, 2006
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4LW3
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137D
| A-DNA DECAMER D(GCGGGCCCGC)-ORTHORHOMBIC CRYSTAL FORM | Descriptor: | DNA (5'-D(*GP*CP*GP*GP*GP*CP*CP*CP*GP*C)-3') | Authors: | Ramakrishnan, B, Sundaralingam, M. | Deposit date: | 1993-09-15 | Release date: | 1994-01-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evidence for crystal environment dominating base sequence effects on DNA conformation: crystal structures of the orthorhombic and hexagonal polymorphs of the A-DNA decamer d(GCGGGCCCGC) and comparison with their isomorphous crystal structures. Biochemistry, 32, 1993
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4EEO
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-GlcNAc-ALPHA-benzyl | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-benzyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4EEM
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-MAN-ALPHA-methyl | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-methyl alpha-D-mannopyranoside, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4EEG
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-beta-D-galactopyranose, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4L41
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4M4K
| Crystal structure of the Drosphila beta,14galactosyltransferase 7 mutant D211N complex with manganese, UDP-Gal and xylobiose | Descriptor: | Beta-4-galactosyltransferase 7, CHLORIDE ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2013-08-07 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding. J.Biol.Chem., 288, 2013
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4EE4
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with tetrasaccharide from Lacto-N-neohexose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4EE5
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with trisaccharide from Lacto-N-neotetraose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4EEA
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-Gal-Beta1,4-Glc-BETA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4EE3
| Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with pentasaccharide | Descriptor: | 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, Beta-1,4-galactosyltransferase 1, GLYCEROL, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2012-03-28 | Release date: | 2012-07-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287, 2012
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4KRV
| Crystal structure of catalytic domain of bovine beta1,4-galactosyltransferase mutant M344H-GalT1 complex with 6-sulfo-GlcNAc | Descriptor: | 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, Beta-1,4-galactosyltransferase 1, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2013-05-17 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Investigations on beta 1,4-galactosyltransferase I using 6-sulfo-GlcNAc as an acceptor sugar substrate. Glycoconj J, 30, 2013
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1TW5
| beta1,4-galactosyltransferase mutant M344H-Gal-T1 in complex with Chitobiose | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | Deposit date: | 2004-06-30 | Release date: | 2004-12-14 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry, 43, 2004
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1YRO
| Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | Authors: | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | Deposit date: | 2005-02-04 | Release date: | 2005-03-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine beta-1,4-Galactosyltransferase I Biochemistry, 44, 2005
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1TW1
| beta-1,4-galactosyltransferase mutant Met344His (m344H-Gal-T1) complex with UDP-galactose and magnesium | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-1,4-galactosyltransferase 1, ... | Authors: | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | Deposit date: | 2004-06-30 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry, 43, 2004
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160D
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