4L41

Human Lactose synthase: A 2:1 complex between human alpha-lactalbumin and human beta1,4-galactosyltransferase

Summary for 4L41

• Entry DOI: 10.2210/pdb4l41/pdb
• Related: 1A4V 1NF5 2AEC 4KRV
• Descriptor: Alpha-lactalbumin, Beta-1,4-galactosyltransferase 1, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: gt-a fold, lactose synthase, substrate binding, golgi, calcium binding protein-transferase complex, calcium binding protein/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00709; Isoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted: P15291
• Total number of polymer chains: 3
• Total formula weight: 61270.91

Authors

Ramakrishnan, B.,Qasba, P.K. (deposition date: 2013-06-07, release date: 2013-10-02, Last modification date: 2023-09-20)

• Primary citation: Ramakrishnan, B.,Qasba, P.K.; Crystal Structure of Human Lactose Synthase forms a Novel 1:2 Complex between beta1,4Galactosyltransferase 1 and alpha-Lactalbumin Proteins; To be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)