4EEM

Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-MAN-ALPHA-methyl

Summary for 4EEM

Entry DOI	10.2210/pdb4eem/pdb
Related	4EE3 4EE4 4EE5 4EEA 4EEG 4EEO
Descriptor	Beta-1,4-galactosyltransferase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-methyl alpha-D-mannopyranoside, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywords	protein carbohydrate interactions, gt-a fold, glycosyltransferase, udp-galactose, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	102602.37
Authors	Ramakrishnan, B.,Qasba, P.K. (deposition date: 2012-03-28, release date: 2012-07-04, Last modification date: 2023-09-13)
Primary citation	Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode. J.Biol.Chem., 287:28666-28674, 2012 Cited by PubMed: 22740701 DOI: 10.1074/jbc.M112.373514 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation