5EX7
| Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA | Descriptor: | Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3') | Authors: | Wang, Y, Yu, Z, Wang, M, Liu, C.P, Yang, N, Xu, R.M. | Deposit date: | 2015-11-23 | Release date: | 2015-12-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA To Be Published
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5EX3
| Crystal structure of human SMYD3 in complex with a VEGFR1 peptide | Descriptor: | ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Qiao, Q, Fu, W, Liu, N, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N. | Deposit date: | 2015-11-23 | Release date: | 2016-03-09 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.408 Å) | Cite: | Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase J.Biol.Chem., 291, 2016
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1CER
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6X3U
| Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus flumazenil | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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7T3N
| R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2) | Descriptor: | (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Vesicular glutamate transporter 2 | Authors: | Li, F, Stroud, R.M, Edwards, R.H. | Deposit date: | 2021-12-08 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter To Be Published
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7T3O
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5EWN
| Crystal structure of the human astrovirus 1 capsid protein core domain at 2.6 A resolution | Descriptor: | CHLORIDE ION, Structural protein | Authors: | York, R.L, Yousefi, P.A, Bogdanoff, W, Haile, S, Tripathi, S, DuBois, R.M. | Deposit date: | 2015-11-20 | Release date: | 2015-12-23 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid. J.Virol., 90, 2015
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5EXU
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6X3S
| Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with bicuculline methbromide | Descriptor: | (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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6WPB
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6WPD
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6X3X
| Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus diazepam | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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1CN4
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6X40
| Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus picrotoxin | Descriptor: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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6RMK
| Bacteriorhodopsin, dark state, cell 2, refined using the same protocol as sub-ps time delays | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Barends, T.R.M, Schlichting, I. | Deposit date: | 2019-05-07 | Release date: | 2019-06-05 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nat Commun, 10, 2019
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6WYJ
| Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog | Authors: | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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6WYL
| Cryo-EM structure of GltPh L152C-G351C mutant in the intermediate outward-facing state. | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog | Authors: | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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6WYK
| Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state. | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog | Authors: | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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1CJD
| THE BACTERIOPHAGE PRD1 COAT PROTEIN, P3, IS STRUCTURALLY SIMILAR TO HUMAN ADENOVIRUS HEXON | Descriptor: | PROTEIN (MAJOR CAPSID PROTEIN (P3)) | Authors: | Benson, S.D, Bamford, J.K.H, Bamford, D.H, Burnett, R.M. | Deposit date: | 1999-04-12 | Release date: | 1999-09-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures. Cell(Cambridge,Mass.), 98, 1999
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6WPO
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7TZF
| Human Amylin3 Receptor in complex with Gs and rat amylin peptide | Descriptor: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | Deposit date: | 2022-02-15 | Release date: | 2022-03-23 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A structural basis for amylin receptor phenotype. Science, 375, 2022
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7TYF
| Human Amylin1 Receptor in complex with Gs and rat amylin peptide | Descriptor: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | Deposit date: | 2022-02-13 | Release date: | 2022-03-23 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | A structural basis for amylin receptor phenotype. Science, 375, 2022
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7TYH
| Human Amylin2 Receptor in complex with Gs and human calcitonin peptide | Descriptor: | Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | Deposit date: | 2022-02-13 | Release date: | 2022-03-23 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A structural basis for amylin receptor phenotype. Science, 375, 2022
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7TYW
| Human Amylin1 Receptor in complex with Gs and salmon calcitonin peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ... | Authors: | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | Deposit date: | 2022-02-14 | Release date: | 2022-03-23 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A structural basis for amylin receptor phenotype. Science, 375, 2022
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7TYO
| Calcitonin receptor in complex with Gs and human calcitonin peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin, ... | Authors: | Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M. | Deposit date: | 2022-02-14 | Release date: | 2022-03-23 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A structural basis for amylin receptor phenotype. Science, 375, 2022
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