6WYL
Cryo-EM structure of GltPh L152C-G351C mutant in the intermediate outward-facing state.
Summary for 6WYL
| Entry DOI | 10.2210/pdb6wyl/pdb |
| EMDB information | 21968 |
| Descriptor | Glutamate transporter homolog, ASPARTIC ACID (2 entities in total) |
| Functional Keywords | glutamate transporter homolog gltph, transport protein |
| Biological source | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
| Total number of polymer chains | 3 |
| Total formula weight | 134154.41 |
| Authors | Font, J.,Chen, I.,Sobti, M.,Stewart, A.G.,Ryan, R.M. (deposition date: 2020-05-13, release date: 2021-02-17, Last modification date: 2024-03-06) |
| Primary citation | Chen, I.,Pant, S.,Wu, Q.,Cater, R.J.,Sobti, M.,Vandenberg, R.J.,Stewart, A.G.,Tajkhorshid, E.,Font, J.,Ryan, R.M. Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591:327-331, 2021 Cited by PubMed: 33597752DOI: 10.1038/s41586-021-03240-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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