6WYK
Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state.
Summary for 6WYK
| Entry DOI | 10.2210/pdb6wyk/pdb |
| EMDB information | 21967 |
| Descriptor | Glutamate transporter homolog, ASPARTIC ACID (2 entities in total) |
| Functional Keywords | glutamate transporter homolog gltph, transport protein |
| Biological source | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
| Total number of polymer chains | 1 |
| Total formula weight | 44718.14 |
| Authors | Font, J.,Chen, I.,Sobti, M.,Stewart, A.G.,Ryan, R.M. (deposition date: 2020-05-13, release date: 2021-02-17, Last modification date: 2024-03-06) |
| Primary citation | Chen, I.,Pant, S.,Wu, Q.,Cater, R.J.,Sobti, M.,Vandenberg, R.J.,Stewart, A.G.,Tajkhorshid, E.,Font, J.,Ryan, R.M. Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591:327-331, 2021 Cited by PubMed: 33597752DOI: 10.1038/s41586-021-03240-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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